Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alexander H. Harkiss"'
Autor:
Shinpei Uno, Alexander H. Harkiss, Roy Chowdhury, Stuart T. Caldwell, Tracy A. Prime, Andrew M. James, Brendan Gallagher, Julien Prudent, Richard C. Hartley, Michael P. Murphy
The targeting of bioactive molecules and probes to mitochondria can be achieved by coupling to the lipophilic triphenyl phosphonium (TPP) cation, which accumulates several hundred-fold within mitochondria in response to the mitochondrial membrane pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95a5af6fe0fa731cdfc5050043de79d
https://www.repository.cam.ac.uk/handle/1810/349471
https://www.repository.cam.ac.uk/handle/1810/349471
Autor:
Michele Cariello, Namrata Pant, Alexander H. Harkiss, Frances M. Tracey, Joseph Cameron, Peter J. Skabara, Peter J. Holliman, Pablo Docampo, Graeme Cooke
Publikováno v:
Molecular Systems Design & Engineering. 7:899-905
Dimer and trimer analogues of Spiro-OMeTAD are porous hole transport materials with improved conductivity compared to the parent material and give higher power conversion efficiencies in perovskite solar cells.
Autor:
Andrew G. Jamieson, Andrew Sutherland, David Nobis, Steven W. Magennis, Eilidh Malcolm, Astrid Knuhtsen, Alexander H. Harkiss, Jonathan D. Bell, Christopher Roland Wellaway
Publikováno v:
Chemical communications (Cambridge, England). 56(12)
The synthesis and photophysical properties of a new class of α-amino acid bearing a rigid pyrazoloquinazoline chromophore are described. Confromational constraint of the amino acid side-chains resulted in high emission quantum yields, while the demo
Publikováno v:
The Journal of Organic Chemistry. 83:535-542
A synthetic route to cis-2-methyl-4-oxo-6-alkylpiperidines has been developed using a 6-endo-trig cyclization of (E)-enones. The base-mediated intramolecular cyclization was found to be general for both alkyl- and aryl-substituted enones, providing t
Autor:
Alexander H. Harkiss, Andrew Sutherland, Ned Buijs, Jonathan D. Bell, Timaeus E. F. Morgan, Christopher Roland Wellaway
Publikováno v:
The Journal of organic chemistry. 84(16)
The synthesis of a new class of benzotriazole-derived α-amino acid is described using a highly efficient nucleophilic aromatic substitution of ortho-fluoronitrobenzenes with l-3-aminoalanine and a ...
Autor:
Andrew Sutherland, Andrew G. Jamieson, Astrid Knuhtsen, Jonathan D. Bell, Alexander H. Harkiss
The preparation of a new class of β-pyridyl α-amino acid is described using a highly regioselective, ytterbium-catalyzed hetero-Diels-Alder reaction of enones with vinyl ethers followed by a modified Knoevenagel-Stobbe reaction as the key heterocyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9df56e281299af3f268c1284c4ecea7
https://eprints.gla.ac.uk/179501/7/179501.pdf
https://eprints.gla.ac.uk/179501/7/179501.pdf
Publikováno v:
Organicbiomolecular chemistry. 16(35)
An acid-mediated 6-endo-trig cyclisation of amine-substituted enones has been developed for the stereoselective synthesis of trans-6-alkyl-2-methyl-4-oxopiperidines. Performed under conditions that prevent removal of the Boc-protecting group or aceta
Publikováno v:
ChemInform. 47
Fluorescence spectroscopy has become a powerful technique for probing a range of complex biological processes including enzyme mechanisms and protein-protein interactions. While the application of this technique uses a number of strategies, many of t
Autor:
Salaheddin A I, Sharif, Ewen D D, Calder, Alexander H, Harkiss, Marie, Maduro, Andrew, Sutherland
Publikováno v:
The Journal of organic chemistry. 81(20)
A four-step synthesis of allylic trichloroacetimidates bearing a 2-proparyloxyaryl group has been developed from readily available 2-hydroxybenzaldehydes, and these have been used for the preparation of allylic amide derived 2H-chromenes using an Ove
Autor:
Lynne Gilfillan, Alexander H. Harkiss, Raik Artschwager, Rob M. J. Liskamp, Andrew Sutherland
Publikováno v:
ChemInform. 46
Using the regioselective transformation of L-aspartic acid derived β-aryl α,β-unsaturated ketones (I) with phenyl hydrazine as a key step, a synthesis of pyrazole-containing α-amino acids (II) is developed.