Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Alexander H, Dalpke"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The discovery of Suppressor of Cytokine Signaling 1 (SOCS1) in 1997 marked a significant milestone in understanding the regulation of Janus kinase/Signal transducer and activator of transcription (JAK/STAT) signaling pathways. Subsequent research dec
Externí odkaz:
https://doaj.org/article/d2926768435a498e933e6a0d4bf7e49d
Autor:
Elisabeth Kahre, Lukas Galow, Manja Unrath, Luise Haag, Judith Blankenburg, Alexander H. Dalpke, Christian Lück, Reinhard Berner, Jakob P. Armann
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract Comparing seroprevalence and antibody kinetics in three different commercially available assays for SARS-CoV-2. Serostatus of COVID-19 patients was analyzed 5 months and 10 months after their infection, using three different assays: Diasorin
Externí odkaz:
https://doaj.org/article/3ad06cb755d9481f99002db848a9c614
Autor:
Michael Sörensen, Bakhodur Khakimov, Dennis Nurjadi, Sébastien Boutin, Buqing Yi, Alexander H. Dalpke, Tatjana Eigenbrod
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 9, Iss 1, Pp 1-7 (2020)
Abstract Long-term treatment with azithromycin is a therapeutic option in Cystic Fibrosis (CF) patients chronically infected with P. aeruginosa. It was recently shown that azithromycin has direct antimicrobial activity when P. aeruginosa isolates are
Externí odkaz:
https://doaj.org/article/ec4940d22e1c45ed961f94fef24681c2
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Chronic Pseudomonas aeruginosa infections play an important role in the progress of lung disease in patients suffering from cystic fibrosis (CF). Recent studies indicate that polymicrobial microbiome profiles in the airway are associated with less in
Externí odkaz:
https://doaj.org/article/7f3f38adb7e84ec3987e0da8b9ede45a
Autor:
Marisa I. Metzger, Simon Y. Graeber, Mirjam Stahl, Olaf Sommerburg, Marcus A. Mall, Alexander H. Dalpke, Sébastien Boutin
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Progressive impairment in lung function caused by chronic polymicrobial airway infection remains the major cause of death in patients with cystic fibrosis (CF). Cross-sectional studies suggest an association between lung function decline and specific
Externí odkaz:
https://doaj.org/article/d8dabac938734fba8d47ad4436fc0d2e
Autor:
Julia Körholz, Anastasia Gabrielyan, John M. Sowerby, Felix Boschann, Lan-Sun Chen, Diana Paul, David Brandt, Janina Kleymann, Martin Kolditz, Nicole Toepfner, Ralf Knöfler, Eva-Maria Jacobsen, Christine Wolf, Karsten Conrad, Nadja Röber, Min Ae Lee-Kirsch, Kenneth G. C. Smith, Stefan Mundlos, Reinhard Berner, Alexander H. Dalpke, Catharina Schuetz, William Rae
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundInborn errors of immunity (IEI) present with a large phenotypic spectrum of disease, which can pose diagnostic and therapeutic challenges. Suppressor of cytokine signaling 1 (SOCS1) is a key negative regulator of cytokine signaling, and has
Externí odkaz:
https://doaj.org/article/157591a72b194f6cb40a244fa421e25e
Autor:
Reinhard Berner, Carolin Kirsten, Christian Lück, Manja Unrath, Alexander H Dalpke, Jakob Armann
Publikováno v:
BMJ Open, Vol 11, Iss 6 (2021)
Objective To quantify the number of SARS-CoV-2 infections in secondary schools after their reopening in May 2020.Design Repeated SARS-CoV-2 seroprevalence study after the reopening of schools and 4 months later.Setting Secondary school in Dresden, Ge
Externí odkaz:
https://doaj.org/article/2e30cd3f24d54132a44eaf45899882e4
Autor:
Felix C. F. Schmitt, Thorsten Brenner, Florian Uhle, Svenja Loesch, Thilo Hackert, Alexis Ulrich, Stefan Hofer, Alexander H. Dalpke, Markus A. Weigand, Sébastien Boutin
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Postoperative complications are of great relevance in daily clinical practice, and the gut microbiome might play an important role by preventing pathogens from crossing the intestinal barrier. The two aims of this prospective clin
Externí odkaz:
https://doaj.org/article/1ef9ec4d684746bcbe1079624bbb721c
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The development of CFTR modulator therapies significantly changed the treatment scheme of people with cystic fibrosis. However, CFTR modulator therapy is still a life-long treatment, which is not able to correct the genetic defect and cure the diseas
Externí odkaz:
https://doaj.org/article/ed11a38fca194ae7bf013760cd0047f4
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Breathing allows a multitude of airborne microbes and microbial compounds to access the lung. Constant exposure of the pulmonary microenvironment to immunogenic particles illustrates the need for proper control mechanisms ensuring the differentiation
Externí odkaz:
https://doaj.org/article/0f860a006b1e43078c3a86ba42922571