Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alexander Gress"'
Autor:
Robert Richter, Mohamed.A.M. Kamal, Mariel A. García-Rivera, Jerome Kaspar, Maximilian Junk, Walid A.M. Elgaher, Sanjay Kumar Srikakulam, Alexander Gress, Anja Beckmann, Alexander Grißmer, Carola Meier, Michael Vielhaber, Olga Kalinina, Anna K.H. Hirsch, Rolf W. Hartmann, Mark Brönstrup, Nicole Schneider-Daum, Claus-Michael Lehr
Publikováno v:
Materials Today Bio, Vol 8, Iss , Pp 100084- (2020)
The pipeline of antibiotics has been for decades on an alarmingly low level. Considering the steadily emerging antibiotic resistance, novel tools are needed for early and easy identification of effective anti-infective compounds. In Gram-negative bac
Externí odkaz:
https://doaj.org/article/abcd928f0e8c4f0e83637af5a24dae36
Autor:
Alexander Gress, Olga V. Kalinina
Publikováno v:
Protein Interactions. :333-357
Publikováno v:
GigaScience
Background Structural annotation of genetic variants in the context of intermolecular interactions and protein stability can shed light onto mechanisms of disease-related phenotypes. Three-dimensional structures of related proteins in complexes with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d676bff9b73510f6aa004f7d33c3b5db
https://hdl.handle.net/21.11116/0000-000B-4789-B21.11116/0000-000B-478B-9
https://hdl.handle.net/21.11116/0000-000B-4789-B21.11116/0000-000B-478B-9
Publikováno v:
Denisov, S 2021, ' An extended catalogue of tandem alternative splice sites in human tissue transcriptomes ', PLoS Computational Biology, vol. 17, no. 4, pp. e1008329 . https://doi.org/10.1371/journal.pcbi.1008329
PLoS Computational Biology
e1008329
PLoS computational biology
United States
PLoS Computational Biology, Vol 17, Iss 4, p e1008329 (2021)
PLoS Computational Biology
e1008329
PLoS computational biology
United States
PLoS Computational Biology, Vol 17, Iss 4, p e1008329 (2021)
Tandem alternative splice sites (TASS) is a special class of alternative splicing events that are characterized by a close tandem arrangement of splice sites. Most TASS lack functional characterization and are believed to arise from splicing noise. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a8592814a574bfcdd1538862f3a852
https://doi.org/10.1371/journal.pcbi.1008329
https://doi.org/10.1371/journal.pcbi.1008329
Autor:
Zakaria Louadi, Tim Kacprowski, Markus List, Kevin Yuan, Alexander Gress, Olga V. Kalinina, Jan Baumbach, Olga Tsoy
Publikováno v:
Nucleic acids research
England
Louadi, Z, Yuan, K, Gress, A, Tsoy, O, Kalinina, O V, Baumbach, J, Kacprowski, T & List, M 2021, ' DIGGER : exploring the functional role of alternative splicing in protein interactions ', Nucleic acids research, vol. 49, no. D1, pp. D309-D318 . https://doi.org/10.1093/nar/gkaa768
Nucleic Acids Research
England
Louadi, Z, Yuan, K, Gress, A, Tsoy, O, Kalinina, O V, Baumbach, J, Kacprowski, T & List, M 2021, ' DIGGER : exploring the functional role of alternative splicing in protein interactions ', Nucleic acids research, vol. 49, no. D1, pp. D309-D318 . https://doi.org/10.1093/nar/gkaa768
Nucleic Acids Research
Alternative splicing plays a major role in regulating the functional repertoire of the proteome. However, isoform-specific effects to protein-protein interactions (PPIs) are usually overlooked, making it impossible to judge the functional role of ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472c983fa11e7e18def3b15dfa22a43b
https://hdl.handle.net/10033/622522
https://hdl.handle.net/10033/622522
Autor:
Rolf W. Hartmann, Alexander Grißmer, Jerome Kaspar, Carola Meier, Walid A. M. Elgaher, Maximilian Junk, Mohamed Ashraf M. Kamal, Anna Hirsch, Anja Beckmann, Olga V. Kalinina, Alexander Gress, Sanjay Kumar Srikakulam, Mariel A. García-Rivera, Michael Vielhaber, Nicole Schneider-Daum, Claus-Michael Lehr, Mark Brönstrup, Robert Richter
Publikováno v:
Materials Today Bio
Materials today. Bio
England
Materials Today Bio, Vol 8, Iss, Pp 100084-(2020)
Materials today. Bio
England
Materials Today Bio, Vol 8, Iss, Pp 100084-(2020)
The pipeline of antibiotics has been for decades on an alarmingly low level. Considering the steadily emerging antibiotic resistance, novel tools are needed for early and easy identification of effective anti-infective compounds. In Gram-negative bac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9c0cc40de63e654fc8b22b164a3ac5
https://doi.org/10.26434/chemrxiv.12709751
https://doi.org/10.26434/chemrxiv.12709751
Autor:
Alexander Gress, Olga V. Kalinina
Publikováno v:
Bioinformatics (Oxford, England)
England
England
Motivation In proteins, solvent accessibility of individual residues is a factor contributing to their importance for protein function and stability. Hence one might wish to calculate solvent accessibility in order to predict the impact of mutations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42034ec6193ed4763ce152fe4b129064
https://hdl.handle.net/10033/622303
https://hdl.handle.net/10033/622303
Publikováno v:
Nucleic Acids Research
The next generation sequencing technologies produce unprecedented amounts of data on the genetic sequence of individual organisms. These sequences carry a substantial amount of variation that may or may be not related to a phenotype. Phenotypically i
Autor:
Christina Backes, Olga V. Kalinina, Oliver Kohlbacher, Andreas Keller, Eckart Meese, Alexander Gress, Andreas Moll, Nina Baumgarten, Sabine C. Mueller
Publikováno v:
Bioinformatics (Oxford, England). 32(12)
Summary: In medical research, it is crucial to understand the functional consequences of genetic alterations, for example, non-synonymous single nucleotide variants (nsSNVs). NsSNVs are known to be causative for several human diseases. However, the g
Publikováno v:
Computer Graphics Forum. 25:497-506
Based on the potential of current programmable GPUs, recently several approaches were developed that use the GPU to calculate deformations of surfaces like the folding of cloth or to convert higher level geometry to renderable primitives like NURBS o