Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alexander Gornikiewicz"'
Autor:
Sandra Varga, Thomas Waerner, Lichun Huang, Alexander Gornikiewicz, Gerhard Loeber, Thomas Girsch
Publikováno v:
Analytical and Bioanalytical Chemistry. 389:2109-2113
Over the last decade biological assays (bioassays) have gained much importance for quality control in biopharmaceutical development and manufacturing. Here we describe the development and validation of a bioassay to determine the biological activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437e0eef28fd29a23a66d945c8a4ded0
https://doi.org/10.1007/s00216-007-1662-8
https://doi.org/10.1007/s00216-007-1662-8
Autor:
Thomas Sautner, P. Götzinger, Michael Bergmann, Dietmar Tamandl, Alexander Gornikiewicz, Reinhold Függer, Ruth Exner, Erich Roth
Publikováno v:
Shock. 20:575-581
Catecholamines play a central role in the treatment of sepsis-associated hypotension. However, these hormones have also been shown to modulate the lipopolysaccharide (LPS)-induced induction of cytokines such as tumor necrosis factor alpha, interleuki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1d0957dbabce77a754842ab833e77f
https://doi.org/10.1097/01.shk.0000095934.86703.83
https://doi.org/10.1097/01.shk.0000095934.86703.83
Autor:
Christine Brostjan, Anton Stift, Anna Zommer, Sebastian Roka, Anita Bayer, Alexander Gornikiewicz, Raimund Jakesz, Rubina Yaghubian, Thomas Benkö, Michael Gnant, Josef Friedl, Günther Steger
Publikováno v:
Cancer. 98:2291-2301
BACKGROUND A promising treatment approach for patients with malignant disease that recently has found its way into clinical trials is based on vaccination with autologous dendritic cells loaded with tumor antigens. However, adequate assays for monito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a95d23c08c047a5417714a9efed9faa
https://doi.org/10.1002/cncr.11776
https://doi.org/10.1002/cncr.11776
Autor:
Reinhold Függer, N. Manhart, Alexander Gornikiewicz, Thomas Sautner, Michael Bergmann, Andreas Spittler, Rudolf Oehler, Erich Roth
Publikováno v:
Clinical Nutrition. 20:37-42
Background & aims: Surgery, trauma and inflammation reduce HLA-DR expression on monocytes, which is associated with an increased susceptibility to infection and sepsis. Furthermore, surgery decreases plasma glutamine (GLN) levels. The expression of H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33f77719ad3d3c8c85b9c4178ed7f7d
https://doi.org/10.1054/clnu.2000.0153
https://doi.org/10.1054/clnu.2000.0153
Publikováno v:
Acta Chirurgica Austriaca. 32:251-254
Grundlagen: Tumorwachstum und Metastasierung erfordern eine ausreichende Versorgung durch Blutgefase, die weitgehend neu gebildet werden mussen. Der Prozes der Angiogenese bietet daher einen vielversprechenden Angriffspunkt in der Tumortherapie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a5e1a7496d03eb113a6ed2ec8a29b54
https://doi.org/10.1007/bf02949148
https://doi.org/10.1007/bf02949148
Autor:
Alexander Franz, Erika Jensen-Jarolim, Wolfgang R. Sperr, A Schedle, Alexander Gornikiewicz, Andreas Spittler, George Boltz-Nitulescu, Xiaohui Rausch-Fan
Publikováno v:
Journal of Biomedical Materials Research. 51:88-95
The influence of dental amalgam and heavy metal cations on interleukin-1beta (IL-1beta) expression by peripheral blood mononuclear cells from healthy donors was studied. A marked decrease in the production of IL-1beta was caused by freshly prepared a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a93d4d3df0010ba199354fc901c1c4b0
https://doi.org/10.1002/(sici)1097-4636(200007)51:1<88::aid-jbm12>3.0.co
https://doi.org/10.1002/(sici)1097-4636(200007)51:1<88::aid-jbm12>3.0.co
Autor:
Erich Roth, Martina Mittlböck, Elke Waldmann, Thomas Sautner, Michael Bergmann, Thomas Weber, Reinhold Függer, Alexander Gornikiewicz
Publikováno v:
Shock. 12:421-427
Studies performed on healthy volunteers have revealed that catecholamines down-regulate the lipopolysaccharide (LPS)-induced production of tumor necrosis factor (TNF)alpha, interleukin (IL)-6, and IL-1beta. We extended this observation and show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9cb17d596972e491ce23eb1eab2abd9
https://doi.org/10.1097/00024382-199912000-00002
https://doi.org/10.1097/00024382-199912000-00002
Autor:
Rudolf Oehler, Erich Roth, Carmen M. Reissner, T. Brodowicz, Andreas Spittler, Thomas Gruenberger, George Boltz-Nitulescu, N. Manhart, Alexander Gornikiewicz, Martina Mittlboeck
Publikováno v:
Europe PubMed Central
Cytokines play a pivotal role in the pathogenesis of septic shock. Proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) stimulate the progression of septic shock whereas the anti-inflammatory cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad88426f25092ff3df183462bf03863
https://doi.org/10.1096/fasebj.13.3.563
https://doi.org/10.1096/fasebj.13.3.563
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
Tumor growth requires the formation of new blood vessels by endothelial cells. Thus, surface molecules -- such as angiogenin receptors -- that are selectively expressed on growing endothelium represent an attractive target for directed delivery of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fafcaeede7b4fa4fdb824628f92e5b
https://pubmed.ncbi.nlm.nih.gov/16175248
https://pubmed.ncbi.nlm.nih.gov/16175248
Autor:
Reinhold Függer, Alexander Gornikiewicz, Erich Roth, Ferdinand Mühlbacher, Thomas Sautner, Michael Bergmann, Christine Brostjan, Bernhard Schmierer
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
The catecholamine-mediated modulation of the cytokine network has primarily been demonstrated for leukocytes. Whereas catecholamines decrease the LPS-induced production of IL-6 by leukocytes, serum levels of IL-6 are dramatically increased by the cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38118aaddb159b19f58b5ad028d525a1
https://pubmed.ncbi.nlm.nih.gov/10834930
https://pubmed.ncbi.nlm.nih.gov/10834930