Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Alexander G. Maier"'
Autor:
Makenna Short, Kira Lowe, Michelle Michie, Ina Smith, Kim Blasdell, Alexander G. Maier, Alexander W. Gofton
Publikováno v:
International Journal for Parasitology: Parasites and Wildlife, Vol 25, Iss , Pp 100982- (2024)
Tick-borne haemoparasites, including piroplasms and trypanosomes, are almost ubiquitous in Australian wildlife, with some associated with health impacts to individual animals and declining wildlife populations. An array of ecologically distinct pirop
Externí odkaz:
https://doaj.org/article/f42cbc1e90244c659ed567ab5bd811b2
Plasmodium falciparum gametocytes display global chromatin remodelling during sexual differentiation
Autor:
Myriam D. Jeninga, Jingyi Tang, Shamista A. Selvarajah, Alexander G. Maier, Michael F. Duffy, Michaela Petter
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-29 (2023)
Abstract Background The protozoan malaria parasite Plasmodium falciparum has a complex life cycle during which it needs to differentiate into multiple morphologically distinct life forms. A key process for transmission of the disease is the developme
Externí odkaz:
https://doaj.org/article/2121ad1a1f8c4a94a6433d804794cc96
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Malaria parasites are unicellular eukaryotic pathogens that develop through a complex lifecycle involving two hosts, an anopheline mosquito and a vertebrate host. Throughout this lifecycle, the parasite encounters widely differing conditions and surv
Externí odkaz:
https://doaj.org/article/c72e313b8ae8429f9bb6b2f2d1bd2d50
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT We developed a flow-cytometry-based method to separate and collect cocultured male and female Plasmodium falciparum gametocytes responsible for malaria transmission. The purity of the collected cells was estimated at >97% using flow cytometr
Externí odkaz:
https://doaj.org/article/5906ad2654734025873316ef91871da1
Autor:
Phuong N. Tran, Cameron J. Tate, Melanie C. Ridgway, Kevin J. Saliba, Kiaran Kirk, Alexander G. Maier
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 6, Iss 3, Pp 179-183 (2016)
Ketotifen has recently been reported to inhibit the growth of both asexual and sexual malaria parasites. A parasite transporter, PfgABCG2, has been implicated in its mechanism of action. Human dihydrofolate reductase (hDHFR) is the most commonly used
Externí odkaz:
https://doaj.org/article/bca708d4dc524a98acefd1eb8a9cff69
Autor:
William Nguyen, Madeline G. Dans, Iain Currie, Jon Kyle Awalt, Brodie L. Bailey, Chris Lumb, Anna Ngo, Paola Favuzza, Josephine Palandri, Saishyam Ramesh, Jocelyn Penington, Kate E. Jarman, Partha Mukherjee, Arnish Chakraborty, Alexander G. Maier, Giel G. van Dooren, Tony Papenfuss, Sergio Wittlin, Alisje Churchyard, Jake Baum, Elizabeth A. Winzeler, Delphine Baud, Stephen Brand, Paul F. Jackson, Alan F. Cowman, Brad E. Sleebs
Publikováno v:
ACS Infectious Diseases. 9:668-691
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e68d5adaecdff89fbbd72ee950fe157
https://doi.org/10.1021/acsinfecdis.2c00607
https://doi.org/10.1021/acsinfecdis.2c00607
Publikováno v:
Emerging Topics in Life Sciences. 7:67-79
Eukaryotic pathogens with an intracellular parasitic lifestyle are shielded from extracellular threats during replication and growth. In addition to many nutrients, parasites scavenge host cell lipids to establish complex membrane structures inside t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d0880b523357e568d4973ef53e93d18
https://doi.org/10.1042/etls20220089
https://doi.org/10.1042/etls20220089
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Malaria parasites are unicellular eukaryotic pathogens that develop through a complex lifecycle involving two hosts, an anopheline mosquito and a vertebrate host. Throughout this lifecycle, the parasite encounters widely differing conditions and surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787cab1747681d583156d193885017a9
https://researchonline.lshtm.ac.uk/id/eprint/4667525/7/Mailer_Ooij_2022_The-role-of-cholesterol-in-invasion.pdf
https://researchonline.lshtm.ac.uk/id/eprint/4667525/7/Mailer_Ooij_2022_The-role-of-cholesterol-in-invasion.pdf
Publikováno v:
Journal of Science & Popular Culture. 3:39-56
With the growing awareness of the contribution of parasites to life, their influences on humans also become clearer. The parasite's footprints can be seen everywhere, in genetics, epidemiology, medicine, history and, as this article clarifies, parasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a89614e1d3c97d5fc5aa5df3d241a1d
https://doi.org/10.1386/jspc_00011_1
https://doi.org/10.1386/jspc_00011_1
Autor:
Jenni A. Hayward, F. Victor Makota, Daniela Cihalova, Esther Rajendran, Soraya M. Zwahlen, Laura Shuttleworth, Ursula Wiedemann, Christina Spry, Kevin J. Saliba, Alexander G. Maier, Giel G. van Dooren
With the advent of resistance to existing treatments, new drugs are needed to combat apicomplexan parasites such as the causative agents of malaria (Plasmodium species) and toxoplasmosis (Toxoplasma gondii). To identify new inhibitors of the mitochon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0722cf1d05140c624f0776a8bc9b0245
https://doi.org/10.1101/2022.02.13.480284
https://doi.org/10.1101/2022.02.13.480284