Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Alexander G. Alexandrovich"'
Autor:
Gali Umschweif, Alexander G Alexandrovich, Victoria Trembovler, Michal Horowitz, Esther Shohami
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76129 (2013)
Preconditioning via heat acclimation (34°C 30 d) results in neuroprotection from traumatic brain injury due to constitutive as well as dynamic changes triggered by the trauma. Among these changes is Akt phosphorylation, which decreases apoptosis and
Externí odkaz:
https://doaj.org/article/17d18baf72ca4ef19e722ce7083215b9
Autor:
Esther Shohami, Alexander G. Alexandrovich, Uriel Elchalal, Philip Lazarovici, Victoria Trembovler, Galit Gincberg
Publikováno v:
Cytotherapy. 20:245-261
Background aims Human umbilical cord blood (HUCB) is an important source of stem cells for therapy of hematopoietic disorders and is a potential therapy for various neurological disorders, including traumatic brain injury (TBI). The expression of ner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e070fd05ad76116b1d8cb6ff147130d5
https://doi.org/10.1016/j.jcyt.2017.11.008
https://doi.org/10.1016/j.jcyt.2017.11.008
Autor:
Esther Shohami, Victoria Trembovler, Alexander G. Alexandrovich, Aviva Breuer, Raphael Mechoulam, Reem Smoum, Aniv Mann
Publikováno v:
Journal of Neuroimmune Pharmacology. 10:356-363
The endocannabinoid (eCB) system helps recovery following traumatic brain injury (TBI). Treatment with 2-arachidonoylglycerol (2-AG), a cerebral eCB ligand, was found to ameliorate the secondary damage. Interestingly, the fatty acid amino acid amide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d5ee6e35b1e05e61a3c4862d3c9468
https://doi.org/10.1007/s11481-015-9595-z
https://doi.org/10.1007/s11481-015-9595-z
Autor:
Galit, Gincberg, Esther, Shohami, Victoria, Trembovler, Alexander G, Alexandrovich, Philip, Lazarovici, Uriel, Elchalal
Publikováno v:
Cytotherapy. 20(2)
Human umbilical cord blood (HUCB) is an important source of stem cells for therapy of hematopoietic disorders and is a potential therapy for various neurological disorders, including traumatic brain injury (TBI). The expression of nerve growth factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::906562575acb4737dcb86da2c02a99ea
https://pubmed.ncbi.nlm.nih.gov/29274773
https://pubmed.ncbi.nlm.nih.gov/29274773
Autor:
Arnon Nagler, Esther Shohami, Galit Gincberg, Hanan Galski, Ilan Matok, Alexander G. Alexandrovich, Peter I. Lelkes, Hadar Arien-Zakay, Sigal Liraz-Zaltsman, Uriel Elchalal, Victoria Trembovler, Gadi Cohen, Philip Lazarovici
Publikováno v:
Journal of Neurotrauma. 31:1405-1416
Treatment of traumatic brain injury (TBI) is still an unmet need. Cell therapy by human umbilical cord blood (HUCB) has shown promising results in animal models of TBI and is under evaluation in clinical trials. HUCB contains different cell populatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717edd962fa7d36ca4c975614c0a9df3
https://doi.org/10.1089/neu.2013.3270
https://doi.org/10.1089/neu.2013.3270
Autor:
Esther Shohami, Larry I. Benowitz, Shlomit Dachir, Victoria Trembovler, Alexander G. Alexandrovich, Dalia Shabashov
Publikováno v:
Brain Research. 1555:78-88
Despite years of research, no effective therapy is yet available for the treatment of traumatic brain injury (TBI). The most prevalent and debilitating features in survivors of TBI are cognitive deficits and motor dysfunction. A potential therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c6be77db24a26252f812e2ff7a674e
https://doi.org/10.1016/j.brainres.2014.01.044
https://doi.org/10.1016/j.brainres.2014.01.044
Autor:
Raphael Mechoulam, Esther Shohami, Dafna Willner, Victoria Trembovler, Ayelet Cohen-Yeshurun, Alexander G. Alexandrovich, Ronen R. Leker
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 33:1242-1250
N-arachidonoyl-L-serine (AraS) is a novel neuroprotective endocannabinoid. We aimed to test the effects of exogenous AraS on neurogenesis after traumatic brain injury (TBI). The effects of AraS on neural progenitor cells (NPC) proliferation, survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e91bbb8cea989b9cb775ed94b0e5e68
https://doi.org/10.1038/jcbfm.2013.75
https://doi.org/10.1038/jcbfm.2013.75
Autor:
Nikolaos Grigoriadis, Esther Shohami, Charles A. Dinarello, Na’ama A. Shein, Constantina Simeonidou, Eleni Polyzoidou, Victoria Trembovler, Athanasios Lourbopoulos, Alexander G. Alexandrovich, Paolo Mascagni
Publikováno v:
The FASEB Journal. 23:4266-4275
Despite efforts aimed at developing novel therapeutics for traumatic brain injury (TBI), no specific pharmacological agent is currently clinically available. Here, we show that the pan-histone deacetylase (HDAC) inhibitor ITF2357, a compound shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac8b6a98c40d229fd2976aedc6a51fa
https://doi.org/10.1096/fj.09-134700
https://doi.org/10.1096/fj.09-134700
Autor:
Alexander G. Alexandrovich, Savvas Grigoriadis, Olga Touloumi, Michal Horowitz, Nikolaos Grigoriadis, Esther Shohami, Gali Umschwief, Na'ama A. Shein, Constantina Simeonidou
Publikováno v:
Brain Research. 1244:132-141
Brain-derived neurotrophic factor (BDNF) conveys neuroprotection in various settings of experimental central nervous system injury. Using a model of endogenous neuroprotection, induced in mice by chronic exposure to moderate ambient heat (heat acclim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd691c53c4279a61ddd0c70f5b40957
https://doi.org/10.1016/j.brainres.2008.09.032
https://doi.org/10.1016/j.brainres.2008.09.032
Autor:
Eduardo Muñoz, Savvas Grigoriadis, Raphael Mechoulam, Victoria Trembovler, Yinon Ben-Neriah, Michael Schmitz, Na'ama A. Shein, Esther Shohami, Constantina Simeonidou, Alexander G. Alexandrovich, Bernd L. Fiebich, Jeanna Tsenter, Arieh Moussaieff
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 28:1341-1352
Boswellia resin has been used as a major anti-inflammatory agent and for the healing of wounds for centuries. Incensole acetate (IA), isolated from this resin, was shown to inhibit the activation of nuclear factor-κB, a key transcription factor in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6fa23a4a1b60e6c945292625681ff0
https://doi.org/10.1038/jcbfm.2008.28
https://doi.org/10.1038/jcbfm.2008.28