Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Alexander G Petrenko"'
Autor:
Amila Zuko, Asami Oguro-Ando, Harm Post, Renske L.R.E. Taggenbrock, Roland E. van Dijk, Maarten Altelaar, Albert J R Heck, Alexander G Petrenko, Bert van der Zwaag, Yasushi Shimoda, R. Jeroen Pasterkamp, J. Peter H. Burbach
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 9 (2016)
In view of important neurobiological functions of the cell adhesion molecule contactin-6 (Cntn6) that have emerged from studies on null-mutant mice and autism spectrum disorders (ASD) patients, we set out to examine pathways underlying functions of C
Externí odkaz:
https://doaj.org/article/c6bf140738f3416cb64bb637ae7ca4b6
Autor:
Alexander S. Goryashchenko, Alexey A. Pakhomov, Anastasia V. Ryabova, Igor D. Romanishkin, Eugene G. Maksimov, Alexander N. Orsa, Oxana V. Serova, Andrey A. Mozhaev, Margarita A. Maksimova, Vladimir I. Martynov, Alexander G. Petrenko, Igor E. Deyev
Publikováno v:
Biosensors, Vol 11, Iss 9, p 340 (2021)
The determination of pH in live cells and tissues is of high importance in physiology and cell biology. In this report, we outline the process of the creation of SypHerExtra, a genetically encoded fluorescent sensor that is capable of measuring extra
Externí odkaz:
https://doaj.org/article/3a83320935f44e76b05940f0f9904047
Autor:
Alexander N. Orsa, Alexander S. Goryashchenko, I. E. Deyev, A. A. Mozhaev, Vladimir I. Martynov, Alexey A. Pakhomov, E. V. Svirshchevskaya, O. V. Serova, Alexander G. Petrenko
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:1060-1065
Recently, fluorescent proteins have become an indispensable tool for in vivo visualization of various processes occurring in living systems, from individual organelles to whole organisms. They allow observing the expression of proteins, their localiz
Autor:
Daria D. Korotkova, Elena A. Gantsova, Alexander S. Goryashchenko, Fedor M. Eroshkin, Oxana V. Serova, Alexey S. Sokolov, Fedor Sharko, Svetlana V. Zhenilo, Natalia Y. Martynova, Alexander G. Petrenko, Andrey G. Zaraisky, Igor E. Deyev
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9250
The orphan insulin receptor-related receptor (IRR) encoded by insrr gene is the third member of the insulin receptor family, also including the insulin receptor (IR) and the insulin-like growth factor receptor (IGF-1R). IRR is the extracellular alkal
Publikováno v:
Russian Journal of Bioorganic Chemistry. 46:506-519
Maintaining pH homeostasis is vital for all mammalian cells since hydrogen and hydroxyl ions perform important functions in the regulation of metabolism. Today, it is believed that maintaining the pH in the neutral range (pH 7.2–7.6) in the nervous
Autor:
Eugene G. Maksimov, Alexander N. Orsa, Alexander G. Petrenko, I.D. Romanishkin, Vladimir I. Martynov, A. A. Mozhaev, Anastasia V. Ryabova, Alexey A. Pakhomov, Margarita A. Maksimova, O. V. Serova, Alexander S. Goryashchenko, I. E. Deyev
Publikováno v:
Biosensors, Vol 11, Iss 340, p 340 (2021)
Biosensors
Volume 11
Issue 9
Biosensors
Volume 11
Issue 9
The determination of pH in live cells and tissues is of high importance in physiology and cell biology. In this report, we outline the process of the creation of SypHerExtra, a genetically encoded fluorescent sensor that is capable of measuring extra
Autor:
Alexander N. Orsa, I. E. Deyev, Alexander G. Petrenko, O. V. Serova, Alexander S. Goryashchenko, A. A. Mozhaev, Anna A Boyko
Publikováno v:
Russian Journal of Bioorganic Chemistry. 45:179-182
The insulin receptor-related receptor (IRR) is a cellular sensor of a weakly alkaline medium. Its spatial structure and the mechanism of activation have not been yet established. In the present work, a system of heterologous expression of full-length
Autor:
Alexander N. Orsa, Tatiana N. Erokhina, I. E. Deyev, Alexander S. Goryashchenko, O. V. Serova, Alexander G. Petrenko, A. A. Mozhaev
Publikováno v:
Biomolecules
Biomolecules, Vol 10, Iss 1060, p 1060 (2020)
Volume 10
Issue 7
Biomolecules, Vol 10, Iss 1060, p 1060 (2020)
Volume 10
Issue 7
To study the structure and function of the pH-regulated receptor tyrosine kinase insulin receptor-related receptor (IRR), а member of the insulin receptor family, we obtained six mouse monoclonal antibodies against the recombinant IRR ectodomain. Th
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1862:2924-2939
Background Intracellular pH underlies most cellular processes. There is emerging evidence of a pH-signaling role in plant cells and microorganisms. Dysregulation of pH is associated with human diseases, such as cancer and Alzheimer's disease. Scope o
Autor:
A. A. Mozhaev, E. A. Zubkov, Alexander G. Petrenko, Natalia A. Chachina, D. M. Shayakhmetova, I. E. Deyev, A. Yu. Morozova, Vladimir P. Chekhonin
Publikováno v:
Neuroscience and Behavioral Physiology. 48:483-487
The tyrosine kinase receptor IRR (insulin receptor-related receptor) can be activated on alkalinization of the cell medium. IRR is detected in organs in contact with fluids with extreme pH values, as well as in certain central nervous system cells, w