Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Alexander G, Maier"'
Autor:
Merryn Fraser, Blake Curtis, Patrick Phillips, Patrick A Yates, Kwong Sum Lam, Otto Netzel, Giel G van Dooren, Alyssa Ingmundson, Kai Matuschewski, Malcolm D McLeod, Alexander G Maier
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 7, Pp 1515-1532 (2024)
Abstract Parasites, such as the malaria parasite P. falciparum, are critically dependent on host nutrients. Interference with nutrient uptake can lead to parasite death and, therefore, serve as a successful treatment strategy. P. falciparum parasites
Externí odkaz:
https://doaj.org/article/ff09ddd81108437faeee65fa9548788b
Autor:
Makenna Short, Kira Lowe, Michelle Michie, Ina Smith, Kim Blasdell, Alexander G. Maier, Alexander W. Gofton
Publikováno v:
International Journal for Parasitology: Parasites and Wildlife, Vol 25, Iss , Pp 100982- (2024)
Tick-borne haemoparasites, including piroplasms and trypanosomes, are almost ubiquitous in Australian wildlife, with some associated with health impacts to individual animals and declining wildlife populations. An array of ecologically distinct pirop
Externí odkaz:
https://doaj.org/article/f42cbc1e90244c659ed567ab5bd811b2
Autor:
Jenni A Hayward, F Victor Makota, Daniela Cihalova, Rachel A Leonard, Esther Rajendran, Soraya M Zwahlen, Laura Shuttleworth, Ursula Wiedemann, Christina Spry, Kevin J Saliba, Alexander G Maier, Giel G van Dooren
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2, p e1011987 (2024)
[This corrects the article DOI: 10.1371/journal.ppat.1011517.].
Externí odkaz:
https://doaj.org/article/c192140a1d294373bec4e82a93a0eb00
Plasmodium falciparum gametocytes display global chromatin remodelling during sexual differentiation
Autor:
Myriam D. Jeninga, Jingyi Tang, Shamista A. Selvarajah, Alexander G. Maier, Michael F. Duffy, Michaela Petter
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-29 (2023)
Abstract Background The protozoan malaria parasite Plasmodium falciparum has a complex life cycle during which it needs to differentiate into multiple morphologically distinct life forms. A key process for transmission of the disease is the developme
Externí odkaz:
https://doaj.org/article/2121ad1a1f8c4a94a6433d804794cc96
Autor:
Jenni A Hayward, F Victor Makota, Daniela Cihalova, Rachel A Leonard, Esther Rajendran, Soraya M Zwahlen, Laura Shuttleworth, Ursula Wiedemann, Christina Spry, Kevin J Saliba, Alexander G Maier, Giel G van Dooren
Publikováno v:
PLoS Pathogens, Vol 19, Iss 7, p e1011517 (2023)
Apicomplexans are widespread parasites of humans and other animals, and include the causative agents of malaria (Plasmodium species) and toxoplasmosis (Toxoplasma gondii). Existing anti-apicomplexan therapies are beset with issues around drug resista
Externí odkaz:
https://doaj.org/article/3a72707fe5c84a1cbf9650cd91318ee5
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Malaria parasites are unicellular eukaryotic pathogens that develop through a complex lifecycle involving two hosts, an anopheline mosquito and a vertebrate host. Throughout this lifecycle, the parasite encounters widely differing conditions and surv
Externí odkaz:
https://doaj.org/article/c72e313b8ae8429f9bb6b2f2d1bd2d50
Autor:
Merryn Fraser, Weidong Jing, Stefan Bröer, Florian Kurth, Leif-Erik Sander, Kai Matuschewski, Alexander G Maier
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009259 (2021)
The human malaria parasite Plasmodium falciparum relies on lipids to survive; this makes its lipid metabolism an attractive drug target. The lipid phosphatidylserine (PS) is usually confined to the inner leaflet of the red blood cell membrane (RBC) b
Externí odkaz:
https://doaj.org/article/cc118066d37e4e7ca40c1cd5cc5a1df2
Autor:
William Nguyen, Madeline G. Dans, Iain Currie, Jon Kyle Awalt, Brodie L. Bailey, Chris Lumb, Anna Ngo, Paola Favuzza, Josephine Palandri, Saishyam Ramesh, Jocelyn Penington, Kate E. Jarman, Partha Mukherjee, Arnish Chakraborty, Alexander G. Maier, Giel G. van Dooren, Tony Papenfuss, Sergio Wittlin, Alisje Churchyard, Jake Baum, Elizabeth A. Winzeler, Delphine Baud, Stephen Brand, Paul F. Jackson, Alan F. Cowman, Brad E. Sleebs
Publikováno v:
ACS Infectious Diseases. 9:668-691
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e68d5adaecdff89fbbd72ee950fe157
https://doi.org/10.1021/acsinfecdis.2c00607
https://doi.org/10.1021/acsinfecdis.2c00607
Publikováno v:
Emerging Topics in Life Sciences. 7:67-79
Eukaryotic pathogens with an intracellular parasitic lifestyle are shielded from extracellular threats during replication and growth. In addition to many nutrients, parasites scavenge host cell lipids to establish complex membrane structures inside t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d0880b523357e568d4973ef53e93d18
https://doi.org/10.1042/etls20220089
https://doi.org/10.1042/etls20220089
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT We developed a flow-cytometry-based method to separate and collect cocultured male and female Plasmodium falciparum gametocytes responsible for malaria transmission. The purity of the collected cells was estimated at >97% using flow cytometr
Externí odkaz:
https://doaj.org/article/5906ad2654734025873316ef91871da1