Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Alexander G, Fletcher"'
Autor:
Christian Cammarota, Nicole S Dawney, Philip M Bellomio, Maren Jüng, Alexander G Fletcher, Tara M Finegan, Dan T Bergstralh
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 4, p e1012001 (2024)
Epithelial tissues are the most abundant tissue type in animals, lining body cavities and generating compartment barriers. The function of a monolayered epithelial tissue-whether protective, secretory, absorptive, or filtrative-relies on the side-by-
Externí odkaz:
https://doaj.org/article/c4e1ec2af1c44925ac01768b342d6c4e
Autor:
Stanley E. Strawbridge, Agata Kurowski, Elena Corujo-Simon, Alastair N. Fletcher, Jennifer Nichols, Alexander G. Fletcher
Publikováno v:
Biology Open, Vol 12, Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/26280dd9559c4df3aea7f56f6a32ae42
Autor:
Sandra Montes-Olivas, Danny Legge, Abbie Lund, Alexander G Fletcher, Ann C Williams, Lucia Marucci, Martin Homer
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1011386 (2023)
Organoids offer a powerful model to study cellular self-organisation, the growth of specific tissue morphologies in-vitro, and to assess potential medical therapies. However, the intrinsic mechanisms of these systems are not entirely understood yet,
Externí odkaz:
https://doaj.org/article/bc64428b884d4479a8b56223f15161f1
Autor:
Alexander Nestor-Bergmann, Guy B Blanchard, Nathan Hervieux, Alexander G Fletcher, Jocelyn Étienne, Bénédicte Sanson
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 1, p e1009812 (2022)
Cell intercalation is a key cell behaviour of morphogenesis and wound healing, where local cell neighbour exchanges can cause dramatic tissue deformations such as body axis extension. Substantial experimental work has identified the key molecular pla
Externí odkaz:
https://doaj.org/article/81f438ab32524d5bb27422fc2d304c9a
Publikováno v:
eLife, Vol 10 (2021)
Bacteria inhibit and kill one another with a diverse array of compounds, including bacteriocins and antibiotics. These attacks are highly regulated, but we lack a clear understanding of the evolutionary logic underlying this regulation. Here, we comb
Externí odkaz:
https://doaj.org/article/10158f84fd7d40dbadb3350330b1b257
Autor:
Rory L. Cooper, Victoria J. Lloyd, Nicolas Di-Poï, Alexander G. Fletcher, Paul M. Barrett, Gareth J. Fraser
Publikováno v:
EvoDevo, Vol 10, Iss 1, Pp 1-11 (2019)
Abstract Background Vertebrates possess a diverse range of integumentary epithelial appendages, including scales, feathers and hair. These structures share extensive early developmental homology, as they mostly originate from a conserved anatomical p
Externí odkaz:
https://doaj.org/article/a3ca00bc744e49e5bd92c655ad0bb226
Publikováno v:
iScience, Vol 17, Iss , Pp 49-66 (2019)
Summary: In developing tissues, sheets of cells become planar polarized, enabling coordination of cell behaviors. It has been suggested that “signaling” of polarity information between cells may occur either bidirectionally or monodirectionally b
Externí odkaz:
https://doaj.org/article/40cab3b0c3784dbd9045661f93d3af6f
Autor:
Leolo Gonay, Catherine Spourquet, Matthieu Baudoin, Ludovic Lepers, Pascale Lemoine, Alexander G. Fletcher, Emmanuel Hanert, Christophe E. Pierreux
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Organogenesis is the phase of embryonic development leading to the formation of fully functional organs. In the case of the thyroid, organogenesis starts from the endoderm and generates a multitude of closely packed independent spherical follicular u
Externí odkaz:
https://doaj.org/article/119b5eaf159c4c53a0bc36334218037c
Autor:
Thomas E. Gorochowski, Sabine Hauert, Jan-Ulrich Kreft, Lucia Marucci, Namid R. Stillman, T.-Y. Dora Tang, Lucia Bandiera, Vittorio Bartoli, Daniel O. R. Dixon, Alex J. H. Fedorec, Harold Fellermann, Alexander G. Fletcher, Tim Foster, Luca Giuggioli, Antoni Matyjaszkiewicz, Scott McCormick, Sandra Montes Olivas, Jonathan Naylor, Ana Rubio Denniss, Daniel Ward
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Many complex behaviors in biological systems emerge from large populations of interacting molecules or cells, generating functions that go beyond the capabilities of the individual parts. Such collective phenomena are of great interest to bioengineer
Externí odkaz:
https://doaj.org/article/1690bd498c644b809310d629489f45c1
Publikováno v:
npj Systems Biology and Applications, Vol 3, Iss 1, Pp 1-12 (2017)
Modelling gene expression and proliferation dynamics of pluripotent stem cells Mouse embryonic stem cells (mESCs) are pluripotent cells, having the potential to turn into most other cell types. A team led by Lucia Marucci at the University of Bristol
Externí odkaz:
https://doaj.org/article/fe7d280fe2fc44c489dde0d578fcc759