Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Alexander F. Rosenberg"'
Autor:
Matthew D. Cheung, Rebecca Asiimwe, Elise N. Erman, Christopher F. Fucile, Shanrun Liu, Chiao-Wang Sun, Vidya Sagar Hanumanthu, Harish C. Pal, Emma D. Wright, Gelare Ghajar-Rahimi, Daniel Epstein, Babak J. Orandi, Vineeta Kumar, Douglas J. Anderson, Morgan E. Greene, Markayla Bell, Stefani Yates, Kyle H. Moore, Jennifer LaFontaine, John T. Killian, Gavin Baker, Jackson Perry, Zayd Khan, Rhiannon Reed, Shawn C. Little, Alexander F. Rosenberg, James F. George, Jayme E. Locke, Paige M. Porrett
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Pig-to-human xenotransplantation is rapidly approaching the clinical arena; however, it is unclear which immunomodulatory regimens will effectively control human immune responses to pig xenografts. Here, we transplant a gene-edited pig kidne
Externí odkaz:
https://doaj.org/article/d52c03551ee848b985332f212612900d
Autor:
Michael Piepenbrink, Fatai Oladunni, Aitor Nogales, Ahmed M. Khalil, Theresa Fitzgerald, Thomas A. Hilimire, Madhubanti Basu, Christopher Fucile, David J. Topham, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/3c461e3578174133b041510e0c25377b
Autor:
Sanghita Sarkar, Dave D. Hill, Alexander F. Rosenberg, Ellen F. Eaton, Olaf Kutsch, James J. Kobie
Publikováno v:
Cells, Vol 13, Iss 12, p 1011 (2024)
The opioid epidemic continues to be a major public health issue that includes millions of people who inject drugs (PWID). PWID have increased incidence of serious infections, including HIV as well as metabolic and inflammatory sequelae. We sought to
Externí odkaz:
https://doaj.org/article/5041e70a560640e49b4487438476f987
Autor:
Michael Piepenbrink, Fatai Oladunni, Aitor Nogales, Ahmed M. Khalil, Theresa Fitzgerald, Madhubanti Basu, Christopher Fucile, David J. Topham, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Due to antigenic drift and shift of influenza A viruses (IAV) and the tendency to elicit predominantly strain-specific antibodies, humanity remains susceptible to new strains of seasonal IAV and is at risk from viruses with pandemic potentia
Externí odkaz:
https://doaj.org/article/ebdd68412b794cc08dc6d57fed2668bf
Autor:
Miranda L. Curtiss, Alexander F. Rosenberg, Christopher D. Scharer, Betty Mousseau, Natalia A. Ballesteros Benavides, John E. Bradley, Beatriz León, Chad Steele, Troy D. Randall, Frances E. Lund
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionData from patient cohorts and mouse models of atopic dermatitis, food allergy and asthma strongly support a role for chitinase-3-like-1 protein (CHI3L1) in allergic disease.MethodsTo address whether Chi3l1 also contributes to TH2 response
Externí odkaz:
https://doaj.org/article/cac7025d889a467685c55cbc25d7bc30
Autor:
Sanghita Sarkar, David A. Spencer, Philip Barnette, Shilpi Pandey, William F. Sutton, Madhubanti Basu, Reuben E. Burch, John D. Cleveland, Alexander F. Rosenberg, Javier Rangel-Moreno, Michael C. Keefer, Ann J. Hessell, Nancy L. Haigwood, James J. Kobie
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Induction of broadly neutralizing antibodies (bNAbs) is a major goal for HIV vaccine development. HIV envelope glycoprotein (Env)-specific bNAbs isolated from HIV-infected individuals exhibit substantial somatic hypermutation and correlate with T fol
Externí odkaz:
https://doaj.org/article/0bc15b6c2dbb4430888df07358991ff5
Autor:
Madhubanti Basu, Michael S. Piepenbrink, Czestochowa Francois, Fritzlaine Roche, Bo Zheng, David A. Spencer, Ann J. Hessell, Christopher F. Fucile, Alexander F. Rosenberg, Catherine A. Bunce, Jane Liesveld, Michael C. Keefer, James J. Kobie
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 2, Pp 100015- (2020)
Summary: Induction of persistent HIV-1 Envelope (Env) specific antibody (Ab) is a primary goal of HIV vaccine strategies; however, it is unclear whether HIV Env immunization in humans induces bone marrow plasma cells, the presumed source of long-live
Externí odkaz:
https://doaj.org/article/0398491330aa4915b0a8c5faedeec230
Autor:
Poulami Basu Thakur, Abagail R. Long, Benjamin J. Nelson, Ranjit Kumar, Alexander F. Rosenberg, Michael J. Gray
Publikováno v:
mSystems, Vol 4, Iss 5 (2019)
ABSTRACT Inflammatory diseases of the gut are associated with increased intestinal oxygen concentrations and high levels of inflammatory oxidants, including hydrogen peroxide (H2O2) and hypochlorous acid (HOCl), which are antimicrobial compounds prod
Externí odkaz:
https://doaj.org/article/8ae048719e8341598290cf3855a23cc3
Autor:
Michael S. Piepenbrink, Aitor Nogales, Madhubanti Basu, Christopher F. Fucile, Jane L. Liesveld, Michael C. Keefer, Alexander F. Rosenberg, Luis Martinez-Sobrido, James J. Kobie
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Although most seasonal inactivated influenza vaccines (IIV) contain neuraminidase (NA), the extent and mechanisms of action of protective human NA-specific humoral responses induced by vaccination are poorly resolved. Due to the propensity o
Externí odkaz:
https://doaj.org/article/486dc477ed854784addaf977de56a6bc
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
To advance our understanding and treatment of disease, research immunologists have been called-upon to place more centralized emphasis on impactful human studies. Such endeavors will inevitably require large-scale study execution and data management
Externí odkaz:
https://doaj.org/article/b9d43aed61224dd297c0de11ca241305