Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alexander F. Pal"'
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 145-156 (2024)
The division of the cellular space into nucleoplasm and cytoplasm promotes quality control mechanisms that prevent misprocessed mRNAs and junk RNAs from gaining access to the translational machinery. Here, we explore how properly processed mRNAs are
Externí odkaz:
https://doaj.org/article/88865b87ba4d4966afe967aed15056fe
Autor:
Alexander O. Serov, Alexey N. Ryabinkin, Alexey S. Vishnevskiy, Sergej Naumov, Alexander F. Pal, Tatyana V. Rakhimova, Dmitry S. Seregin, Konstantin A. Vorotilov, Mikhail R. Baklanov
Publikováno v:
Plasma Processes and Polymers. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b30373325b18d23fa6bc3d5d9bc853eb
https://doi.org/10.1002/ppap.202200169
https://doi.org/10.1002/ppap.202200169
Autor:
Yi Qiu, Yoon Mo Kang, Christopher Korfmann, Fanny Pouyet, Andrew Eckford, Alexander F. Palazzo
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-21 (2024)
Abstract Background In vertebrates, most protein-coding genes have a peak of GC-content near their 5′ transcriptional start site (TSS). This feature promotes both the efficient nuclear export and translation of mRNAs. Despite the importance of GC-c
Externí odkaz:
https://doaj.org/article/4d6e819d1914485eb98112d2551117af
Autor:
V. Talya Yerlici, Audrey Astori, Nevraj S. Kejiou, Chris A. Jordan, Negin Khosraviani, Janet N.Y. Chan, Razqallah Hakem, Brian Raught, Alexander F. Palazzo, Karim Mekhail
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113891- (2024)
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hinders host gene expression, curbing defenses and licensing viral protein synthesis and virulence. During SARS-CoV-2 infection, the virulence factor non-structural protein 1 (Nsp1
Externí odkaz:
https://doaj.org/article/9e4365a8fcd54a9cb81200c0431b45c3
Autor:
Benoît Gouy, Adrien Decorsière, Sophie Desgraupes, Wenming Duan, Hong Ouyang, Yifan E. Wang, E. Ann Yeh, Alexander F. Palazzo, Theo J. Moraes, Sébastien Nisole, Nathalie J. Arhel
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Acute necrotizing encephalopathy 1 (ANE1) is a very rare disorder associated with a dominant heterozygous mutation in the RANBP2 (RAN binding protein 2) gene. ANE1 is frequently triggered by a febrile infection and characterized by serious and irreve
Externí odkaz:
https://doaj.org/article/89f0d98b71104f8e9ff390c2e0630eff
Publikováno v:
Nucleus, Vol 13, Iss 1, Pp 154-169 (2022)
Dominant missense mutations in RanBP2/Nup358 cause Acute Necrotizing Encephalopathy (ANE), a pediatric disease where seemingly healthy individuals develop a cytokine storm that is restricted to the central nervous system in response to viral infectio
Externí odkaz:
https://doaj.org/article/1c000b1d2bc4405ebf7a990e65168888
Autor:
Alexander F. Palazzo, Nevraj S. Kejiou
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
With the discovery of the double helical structure of DNA, a shift occurred in how biologists investigated questions surrounding cellular processes, such as protein synthesis. Instead of viewing biological activity through the lens of chemical reacti
Externí odkaz:
https://doaj.org/article/8e21a777f9eb499ab7eeaebdfb38bc03
Autor:
D.A. Areshkin, John J. Hren, Victor V. Zhirnov, Donald W. Brenner, Alexander F. Pal, Olga Shenderova
Publikováno v:
MRS Proceedings. 621
The electronic structure of nanodiamond clusters containing between 34 and 913 carbon atoms was calculated using a tight-binding Hamiltonian. All clusters had shapes represented by an octahedron with (111) facets with the top and the bottom vertices
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5db427f943a16088b7dc36d430bc61a7
https://doi.org/10.1557/proc-621-r5.16.1
https://doi.org/10.1557/proc-621-r5.16.1
Autor:
Eric J. Wolf, Amanda Miles, Eliza S. Lee, Syed Nabeel-Shah, Jack F. Greenblatt, Alexander F. Palazzo, Vincent Tropepe, Andrew Emili
Publikováno v:
Cell Reports, Vol 31, Iss 8, Pp - (2020)
Summary: The mammalian mRNA nuclear export process is thought to terminate at the cytoplasmic face of the nuclear pore complex through ribonucleoprotein remodeling. We conduct a stringent affinity-purification mass-spectrometry-based screen of the ph
Externí odkaz:
https://doaj.org/article/88c961de50584efa97385dcc678b7a45
Autor:
Franka Voigt, Hui Zhang, Xianying A. Cui, Désirée Triebold, Ai Xin Liu, Jan Eglinger, Eliza S. Lee, Jeffrey A. Chao, Alexander F. Palazzo
Publikováno v:
Cell Reports, Vol 21, Iss 13, Pp 3740-3753 (2017)
It is well established that mRNAs encoding secretory or membrane-bound proteins are translated on the surface of the endoplasmic reticulum (ER). The extent to which mRNAs that encode cytosolic proteins associate with the ER, however, remains controve
Externí odkaz:
https://doaj.org/article/9d4f1d59d8274315879d5847c5e2aba5