Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Alexander F Yakunin"'
Autor:
Yi‐Fan Xu, Fabien Létisse, Farnaz Absalan, Wenyun Lu, Ekaterina Kuznetsova, Greg Brown, Amy A Caudy, Alexander F Yakunin, James R Broach, Joshua D Rabinowitz
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-12 (2013)
Abstract Nucleotide degradation is a universal metabolic capability. Here we combine metabolomics, genetics and biochemistry to characterize the yeast pathway. Nutrient starvation, via PKA, AMPK/SNF1, and TOR, triggers autophagic breakdown of ribosom
Externí odkaz:
https://doaj.org/article/3604c67e8fc44eb89cba3406fe3e0b45
Autor:
Kaushik Raj, Naveen Venayak, Patrick Diep, Sai Akhil Golla, Alexander F. Yakunin, Radhakrishnan Mahadevan
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-16 (2021)
Abstract Background Microorganisms can be metabolically engineered to produce a wide range of commercially important chemicals. Advancements in computational strategies for strain design and synthetic biological techniques to construct the designed s
Externí odkaz:
https://doaj.org/article/134cdc1cc4a344f996b94fc0f713da32
Autor:
Drago Haas, Antje M. Thamm, Jiayi Sun, Lili Huang, Lijie Sun, Guillaume A. W. Beaudoin, Kim S. Wise, Claudia Lerma-Ortiz, Steven D. Bruner, Marian Breuer, Zaida Luthey-Schulten, Jiusheng Lin, Mark A. Wilson, Greg Brown, Alexander F. Yakunin, Inna Kurilyak, Jacob Folz, Oliver Fiehn, John I. Glass, Andrew D. Hanson, Christopher S. Henry, Valérie de Crécy-Lagard
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Analysis of the genes retained in the minimized Mycoplasma JCVI-Syn3A genome established that systems that repair or preempt metabolite damage are essential to life. Several genes known to have such functions were identified and experimental
Externí odkaz:
https://doaj.org/article/71126318982049979973bef57993dd2a
Autor:
Patrick Diep, Jose L. Cadavid, Alexander F. Yakunin, Alison P. McGuigan, Radhakrishnan Mahadevan
Publikováno v:
HardwareX, Vol 11, Iss , Pp e00291- (2022)
Protein purification is a ubiquitous procedure in biochemistry and the life sciences, and represents a key step in the protein production pipeline. The need for scalable and parallel protein purification systems is driven by the demands for increasin
Externí odkaz:
https://doaj.org/article/ce48eb3b374d41f68cdaa74293e1e487
Autor:
Yilan Liu, Jinjin Chen, Anna N. Khusnutdinova, Kevin Correia, Patrick Diep, Khorcheska A. Batyrova, Kayla Nemr, Robert Flick, Peter Stogios, Alexander F. Yakunin, Radhakrishnan Mahadevan
Publikováno v:
Biotechnology for Biofuels, Vol 13, Iss 1, Pp 1-11 (2020)
Abstract Background Aldehyde decarbonylases (ADs), which convert acyl aldehydes into alkanes, supply promising solution for producing alkanes from renewable feedstock. However the instability of ADs impedes their further application. Therefore, the c
Externí odkaz:
https://doaj.org/article/93d07098518a4a90be124e25301b96fc
Autor:
Kaushik Raj, Siavash Partow, Kevin Correia, Anna N. Khusnutdinova, Alexander F. Yakunin, Radhakrishnan Mahadevan
Publikováno v:
Metabolic Engineering Communications, Vol 6, Iss , Pp 28-32 (2018)
Adipic acid is an important industrial chemical used in the synthesis of nylon-6,6. The commercial synthesis of adipic acid uses petroleum-derived benzene and releases significant quantities of greenhouse gases. Biocatalytic production of adipic acid
Externí odkaz:
https://doaj.org/article/a54cc95a39194f7cabcbccf8bd2111cf
Autor:
Sofia Bonilla, Zahra Choolaei, Torsten Meyer, Elizabeth A. Edwards, Alexander F. Yakunin, D. Grant Allen
Publikováno v:
Biotechnology Reports, Vol 17, Iss C, Pp 77-85 (2018)
Anaerobic digestion of biosludge has not yet been implemented in pulp mills due to low biogas yields. Enzymatic pretreatment of biosludge has shown improvements in biogas yields but results are varied. A key limitation of previous studies is that the
Externí odkaz:
https://doaj.org/article/fbaf835d285f4a58a32d32945df97311
Metabolic and evolutionary patterns in the extremely acidophilic archaeon Ferroplasma acidiphilum YT
Autor:
Olga V. Golyshina, Hai Tran, Oleg N. Reva, Sofia Lemak, Alexander F. Yakunin, Alexander Goesmann, Taras Y. Nechitaylo, Violetta LaCono, Francesco Smedile, Alexei Slesarev, David Rojo, Coral Barbas, Manuel Ferrer, Michail M. Yakimov, Peter N. Golyshin
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Ferroplasmaceae represent ubiquitous iron-oxidising extreme acidophiles with a number of unique physiological traits. In a genome-based study of Ferroplasma acidiphilum YT, the only species of the genus Ferroplasma with a validly published n
Externí odkaz:
https://doaj.org/article/629dac02ca6a479a8117a205e987ca69
Autor:
Margot Karlikow, Evan Amalfitano, Xiaolong Yang, Jennifer Doucet, Abigail Chapman, Peivand Sadat Mousavi, Paige Homme, Polina Sutyrina, Winston Chan, Sofia Lemak, Alexander F. Yakunin, Adam G. Dolezal, Shana Kelley, Leonard J. Foster, Brock A. Harpur, Keith Pardee
Publikováno v:
Nature Communications. 14
Nucleic acid sensing powered by the sequence recognition of CRIPSR technologies has enabled major advancement toward rapid, accurate and deployable diagnostics. While exciting, there are still many challenges facing their practical implementation, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d10f6a05926b1bbec078a87d515845ef
https://doi.org/10.1038/s41467-023-36874-6
https://doi.org/10.1038/s41467-023-36874-6
Autor:
Alla Gagarinova, Geordie Stewart, Bahram Samanfar, Sadhna Phanse, Carl A. White, Hiroyuki Aoki, Viktor Deineko, Natalia Beloglazova, Alexander F. Yakunin, Ashkan Golshani, Eric D. Brown, Mohan Babu, Andrew Emili
Publikováno v:
Cell Reports, Vol 17, Iss 3, Pp 904-916 (2016)
Bacterial protein synthesis is an essential, conserved, and environmentally responsive process. Yet, many of its components and dependencies remain unidentified. To address this gap, we used quantitative synthetic genetic arrays to map functional rel
Externí odkaz:
https://doaj.org/article/dac41ea360a046c5a5f5850ed06d8be2