Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Alexander F Yakunin"'
Autor:
Margot Karlikow, Evan Amalfitano, Xiaolong Yang, Jennifer Doucet, Abigail Chapman, Peivand Sadat Mousavi, Paige Homme, Polina Sutyrina, Winston Chan, Sofia Lemak, Alexander F. Yakunin, Adam G. Dolezal, Shana Kelley, Leonard J. Foster, Brock A. Harpur, Keith Pardee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Nucleic acid sensing involving CRISPR technologies is powerful but has certain limitations, such as PAM sequence requirements and limited multiplexing. Here, authors report a CRISPR-based barcoding technology which enables multiple outputs from any t
Externí odkaz:
https://doaj.org/article/d7000d2dde064ed7bf34db5ecc9e93ca
Autor:
Patrick Diep, Heping Leo Shen, Julian A. Wiesner, Nadia Mykytczuk, Vladimiros Papangelakis, Alexander F. Yakunin, Radhakrishnan Mahadevan
Publikováno v:
Engineering in Life Sciences, Vol 23, Iss 7, Pp n/a-n/a (2023)
Abstract Mine wastewater often contains dissolved metals at concentrations too low to be economically extracted by existing technologies, yet too high for environmental discharge. The most common treatment is chemical precipitation of the dissolved m
Externí odkaz:
https://doaj.org/article/cbb1f55239844264882cecb4de1bb656
Autor:
Kaushik Raj, Naveen Venayak, Patrick Diep, Sai Akhil Golla, Alexander F. Yakunin, Radhakrishnan Mahadevan
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-16 (2021)
Abstract Background Microorganisms can be metabolically engineered to produce a wide range of commercially important chemicals. Advancements in computational strategies for strain design and synthetic biological techniques to construct the designed s
Externí odkaz:
https://doaj.org/article/134cdc1cc4a344f996b94fc0f713da32
Autor:
Drago Haas, Antje M. Thamm, Jiayi Sun, Lili Huang, Lijie Sun, Guillaume A. W. Beaudoin, Kim S. Wise, Claudia Lerma-Ortiz, Steven D. Bruner, Marian Breuer, Zaida Luthey-Schulten, Jiusheng Lin, Mark A. Wilson, Greg Brown, Alexander F. Yakunin, Inna Kurilyak, Jacob Folz, Oliver Fiehn, John I. Glass, Andrew D. Hanson, Christopher S. Henry, Valérie de Crécy-Lagard
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Analysis of the genes retained in the minimized Mycoplasma JCVI-Syn3A genome established that systems that repair or preempt metabolite damage are essential to life. Several genes known to have such functions were identified and experimental
Externí odkaz:
https://doaj.org/article/71126318982049979973bef57993dd2a
Autor:
Patrick Diep, Jose L. Cadavid, Alexander F. Yakunin, Alison P. McGuigan, Radhakrishnan Mahadevan
Publikováno v:
HardwareX, Vol 11, Iss , Pp e00291- (2022)
Protein purification is a ubiquitous procedure in biochemistry and the life sciences, and represents a key step in the protein production pipeline. The need for scalable and parallel protein purification systems is driven by the demands for increasin
Externí odkaz:
https://doaj.org/article/ce48eb3b374d41f68cdaa74293e1e487
Autor:
Yilan Liu, Jinjin Chen, Anna N. Khusnutdinova, Kevin Correia, Patrick Diep, Khorcheska A. Batyrova, Kayla Nemr, Robert Flick, Peter Stogios, Alexander F. Yakunin, Radhakrishnan Mahadevan
Publikováno v:
Biotechnology for Biofuels, Vol 13, Iss 1, Pp 1-11 (2020)
Abstract Background Aldehyde decarbonylases (ADs), which convert acyl aldehydes into alkanes, supply promising solution for producing alkanes from renewable feedstock. However the instability of ADs impedes their further application. Therefore, the c
Externí odkaz:
https://doaj.org/article/93d07098518a4a90be124e25301b96fc
Autor:
Kaushik Raj, Siavash Partow, Kevin Correia, Anna N. Khusnutdinova, Alexander F. Yakunin, Radhakrishnan Mahadevan
Publikováno v:
Metabolic Engineering Communications, Vol 6, Iss , Pp 28-32 (2018)
Adipic acid is an important industrial chemical used in the synthesis of nylon-6,6. The commercial synthesis of adipic acid uses petroleum-derived benzene and releases significant quantities of greenhouse gases. Biocatalytic production of adipic acid
Externí odkaz:
https://doaj.org/article/a54cc95a39194f7cabcbccf8bd2111cf
Autor:
Sofia Bonilla, Zahra Choolaei, Torsten Meyer, Elizabeth A. Edwards, Alexander F. Yakunin, D. Grant Allen
Publikováno v:
Biotechnology Reports, Vol 17, Iss C, Pp 77-85 (2018)
Anaerobic digestion of biosludge has not yet been implemented in pulp mills due to low biogas yields. Enzymatic pretreatment of biosludge has shown improvements in biogas yields but results are varied. A key limitation of previous studies is that the
Externí odkaz:
https://doaj.org/article/fbaf835d285f4a58a32d32945df97311
Metabolic and evolutionary patterns in the extremely acidophilic archaeon Ferroplasma acidiphilum YT
Autor:
Olga V. Golyshina, Hai Tran, Oleg N. Reva, Sofia Lemak, Alexander F. Yakunin, Alexander Goesmann, Taras Y. Nechitaylo, Violetta LaCono, Francesco Smedile, Alexei Slesarev, David Rojo, Coral Barbas, Manuel Ferrer, Michail M. Yakimov, Peter N. Golyshin
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Ferroplasmaceae represent ubiquitous iron-oxidising extreme acidophiles with a number of unique physiological traits. In a genome-based study of Ferroplasma acidiphilum YT, the only species of the genus Ferroplasma with a validly published n
Externí odkaz:
https://doaj.org/article/629dac02ca6a479a8117a205e987ca69
Autor:
Alla Gagarinova, Geordie Stewart, Bahram Samanfar, Sadhna Phanse, Carl A. White, Hiroyuki Aoki, Viktor Deineko, Natalia Beloglazova, Alexander F. Yakunin, Ashkan Golshani, Eric D. Brown, Mohan Babu, Andrew Emili
Publikováno v:
Cell Reports, Vol 17, Iss 3, Pp 904-916 (2016)
Bacterial protein synthesis is an essential, conserved, and environmentally responsive process. Yet, many of its components and dependencies remain unidentified. To address this gap, we used quantitative synthetic genetic arrays to map functional rel
Externí odkaz:
https://doaj.org/article/dac41ea360a046c5a5f5850ed06d8be2