Synthesis, physico-chemical properties and effect of adenosine thiamine triphosphate on vitamin B

Autor: Alexander F, Makarchikov, Tatsiana G, Kudyrka, Tatyana A, Luchko, Aliaksei V, Yantsevich, Iryna M, Rusina, Alena A, Makar, Iryna K, Kolas, Sergey A, Usanov

Publikováno v: Biochimica et biophysica acta. General subjects. 1866(4)

Adenosine thiamine triphosphate (AThTP) is a nucleotide discovered in bacteria and some other living organisms more than a decade ago. No biochemical function for AThTP has been established yet, however, experimental data available indicate its possi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b4d22443a71bf1455a287cf5a8ce3783
https://pubmed.ncbi.nlm.nih.gov/35016976

Pig tissues express a catalytically inefficient 25-kDa thiamine triphosphatase: Insight in the catalytic mechanisms of this enzyme

Autor: Thierry Grisar, Jan Czerniecki, Pierre Wins, Ilca Margineanu, Lucien Bettendorff, Bernard Coumans, Bernard Lakaye, Piotr Szyniarowski, Alexander F Makarchikov

Publikováno v: Biochimica et Biophysica Acta (BBA) - General Subjects. 1725:93-102

Thiamine triphosphate (ThTP) is found in most organisms and may be an intracellular signal molecule produced in response to stress. We have recently cloned the cDNA coding for a highly specific mammalian 25-kDa thiamine triphosphatase. The enzyme was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f0ed8f623e18311f8404e887bfa67f
https://doi.org/10.1016/j.bbagen.2005.05.026

Human recombinant thiamine triphosphatase: purification, secondary structure and catalytic properties

Autor: Bernard Lakaye, Benaissa El Moualij, Ridha Aichour, Laurence Lins, Ilca Margineanu, Pierre Wins, Willy Zorzi, Thierry Grisar, Bernard Coumans, Lucien Bettendorff, Luc Lebeau, Alexander F Makarchikov, Séverine Roland

Publikováno v: The International Journal of Biochemistry & Cell Biology
The International Journal of Biochemistry & Cell Biology, 2004, 36 (7), pp.1348-1364. ⟨10.1016/j.biocel.2003.11.013⟩

Thiamine triphosphate (ThTP) is found in most living organisms and it may act as a phosphate donor for protein phosphorylation. We have recently cloned the cDNA coding for a highly specific mammalian 25 kDa thiamine triphosphatase (ThTPase; EC 3.6.1.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b5951cc6fbb76d433f9e6c07d3d8df
https://doi.org/10.1016/j.biocel.2003.11.013

Molecular Characterization of a Specific Thiamine Triphosphatase Widely Expressed in Mammalian Tissues

Autor: Pierre Wins, Bernard Lakaye, Willy Zorzi, Bernard Coumans, Lucien Bettendorff, Thierry Grisar, Alexander F Makarchikov, Adelio Fernandes Antunes, Edwin De Pauw

Publikováno v: Journal of Biological Chemistry. 277:13771-13777

Thiamine triphosphate (ThTP) is found at low concentrations in most animal tissues, and recent data suggest that it may act as a phosphate donor for the phosphorylation of some proteins. In the mammalian brain, ThTP synthesis is rapid, but its steady

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d7d22156dee8f794e6d6eaefeb2311
https://doi.org/10.1074/jbc.m111241200

Adenylate kinase-independent thiamine triphosphate accumulation under severe energy stress in Escherichia coli

Autor: Bernard Lakaye, Pierre Wins, Lucien Bettendorff, Tiziana Gigliobianco, Alexander F Makarchikov

Publikováno v: BMC Microbiology, Vol 8, Iss 1, p 16 (2008)
BMC Microbiology

Background Thiamine triphosphate (ThTP) exists in most organisms and might play a role in cellular stress responses. In E. coli, ThTP is accumulated in response to amino acid starvation but the mechanism of its synthesis is still a matter of controve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b775d1354c78d78359fbaa972f759419
http://www.biomedcentral.com/1471-2180/8/16