Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alexander F J van Aken"'
Autor:
Kumar N Alagramam, Richard J Goodyear, Ruishuang Geng, David N Furness, Alexander F J van Aken, Walter Marcotti, Corné J Kros, Guy P Richardson
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19183 (2011)
Immunocytochemical studies have shown that protocadherin-15 (PCDH15) and cadherin-23 (CDH23) are associated with tip links, structures thought to gate the mechanotransducer channels of hair cells in the sensory epithelia of the inner ear. The present
Externí odkaz:
https://doaj.org/article/af12369a59c14234825c2c698e648e37
Autor:
Elisa Caberlotto, Jean-Yves Tinevez, Christine Petit, Christophe Houbron, Guy P. Richardson, Emilie Bizard, Pascal Martin, Vincent Michel, Nicolas Michalski, Alexander F. J. van Aken, Gaelle M. Lefèvre, Jean-Pierre Hardelin, Corné J. Kros, Dominique Weil
Publikováno v:
Pflügers Archiv European Journal of Physiology
Pflügers Archiv European Journal of Physiology, Springer Verlag, 2009, 459 (1), pp.115-130. ⟨10.1007/s00424-009-0711-x⟩
Pflügers Archiv European Journal of Physiology, 2009, 459 (1), pp.115-130. ⟨10.1007/s00424-009-0711-x⟩
Pflugers Archiv
Pflügers Archiv European Journal of Physiology, Springer Verlag, 2009, 459 (1), pp.115-130. ⟨10.1007/s00424-009-0711-x⟩
Pflügers Archiv European Journal of Physiology, 2009, 459 (1), pp.115-130. ⟨10.1007/s00424-009-0711-x⟩
Pflugers Archiv
We assessed the involvement of harmonin-b, a submembranous protein containing PDZ domains, in the mechanoelectrical transduction machinery of inner ear hair cells. Harmonin-b is located in the region of the upper insertion point of the tip link that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30170a16182dc70326ed67813e5e6f4
https://doi.org/10.1007/s00424-009-0711-x
https://doi.org/10.1007/s00424-009-0711-x
Autor:
Alexander F. J. van Aken, Konrad Noben-Trauth, Walter Marcotti, Richard J. Goodyear, Jane E. Bryant, Corné J. Kros, Margaret Atiba-Davies, Guy P. Richardson
Publikováno v:
The Journal of Physiology. 586:5403-5418
TRPML3 (mucolipin-3) belongs to one of the transient-receptor-potential (TRP) ion channel families. Mutations in the Trpml3 gene cause disorganization of the stereociliary hair bundle, structural aberrations in outer and inner hair cells and stria va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9db77529946eb2924c8a19239f3f21fd
https://doi.org/10.1113/jphysiol.2008.156992
https://doi.org/10.1113/jphysiol.2008.156992
Autor:
Michael E. Schnee, Corné J. Kros, Math P. Cuajungco, Anthony J. Ricci, Stefan Heller, Alexander F. J. van Aken, Simone Jörs, Christian Grimm
Publikováno v:
Proceedings of the National Academy of Sciences. 104:19583-19588
Homozygote varitint-waddler ( Va ) mice, expressing a mutant isoform (A419P) of TRPML3 (mucolipin 3), are profoundly deaf and display vestibular and pigmentation deficiencies, sterility, and perinatal lethality. Here we show that the varitint-waddler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcd50243c9fe24f7d3f78b81638e0e4
https://doi.org/10.1073/pnas.0709846104
https://doi.org/10.1073/pnas.0709846104
Autor:
Alexander F. J. van Aken, Ruishuang Geng, David N. Furness, Corné J. Kros, Walter Marcotti, Guy P. Richardson, Kumar N. Alagramam, Richard J. Goodyear
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 4, p e19183 (2011)
PLoS ONE, Vol 6, Iss 4, p e19183 (2011)
Immunocytochemical studies have shown that protocadherin-15 (PCDH15) and cadherin-23 (CDH23) are associated with tip links, structures thought to gate the mechanotransducer channels of hair cells in the sensory epithelia of the inner ear. The present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4b398251492691753ae9e1fefe7785
http://europepmc.org/articles/PMC3080917
http://europepmc.org/articles/PMC3080917