Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alexander Emmott"'
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202526 (2018)
Wall shear stress gradients (WSSGs) induce an inflammatory phenotype in endothelial cells (ECs) which is hypothesized to be mediated by mechanotransduction through the EC glycocalyx (GCX). We used a three-dimensional in vitro cell culture model with
Externí odkaz:
https://doaj.org/article/8c4e4b99a4ed4d5ab88e3f7c2e5f393c
Autor:
Nastaran Shahmansouri, Mohammed Alreshidan, Alexander Emmott, Kevin Lachapelle, Ismaïl El-Hamamsy, Raymond Cartier, Richard L. Leask, Rosaire Mongrain
Publikováno v:
Materials, Vol 9, Iss 11, p 867 (2016)
An aortic aneurysm is a lethal arterial disease that mainly occurs in the thoracic and abdominal regions of the aorta. Thoracic aortic aneurysms are prevalent in the root/ascending parts of the aorta and can lead to aortic rupture resulting in the su
Externí odkaz:
https://doaj.org/article/cac79f81bb334d90bd25aa426f5a67ea
Autor:
Alexander Emmott, Ali Alakhtar, Rosaire Mongrain, Cornelius Hart, Kevin Lachapelle, Richard L. Leask
Publikováno v:
BMJ Simul Technol Enhanc Learn
IntroductionThree-dimensional (3D) printed multimaterial ascending aortic simulators were created to evaluate the ability of polyjet technology to replicate the distensibility of human aortic tissue when perfused at physiological pressures.MethodsSim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b93285180241e7943b5550da3aabec7
https://doi.org/10.1136/bmjstel-2021-000868
https://doi.org/10.1136/bmjstel-2021-000868
Autor:
Laurence Lefebvre, Louis Villeneuve, Alexander Emmott, Vanessa Hertig, Ismail El-Hamamsy, Richard L. Leask, Angelino Calderone, Alexandre Bergeron
Publikováno v:
Canadian Journal of Cardiology. 37:47-56
Clinical studies have revealed a greater risk of pulmonary autograft dilation after the Ross procedure in patients with preoperative aortic insufficiency (AI). The present study examined whether the morphologic, biomechanical, and cellular properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a487e972d9956a8db5bc7ead18dbe4
https://doi.org/10.1016/j.cjca.2020.02.074
https://doi.org/10.1016/j.cjca.2020.02.074
Autor:
Edgardo Alonso, Alexander Emmott, Yue Xuan, François-Pierre Mongeon, Zhongjie Wang, Ismail El-Hamamsy, Liang Ge, Richard L. Leask, Elaine E. Tseng, Shalni Kumar
Publikováno v:
J Thorac Cardiovasc Surg
The Journal of thoracic and cardiovascular surgery, vol 164, iss 6
The Journal of thoracic and cardiovascular surgery, vol 164, iss 6
ObjectiveThe Ross procedure is an excellent option for children or young adults who need aortic valve replacement because it can restore survival to that of the normal aged-matched population. However, autograft remodeling can lead to aneurysmal form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63642aac909f1aa94018be6672326ef2
https://europepmc.org/articles/PMC8882694/
https://europepmc.org/articles/PMC8882694/
Autor:
Ismail El-Hamamsy, François-Pierre Mongeon, Yue Xuan, Richard L. Leask, Alexander Emmott, Zhongjie Wang, Liang Ge, Shalni Kumar, Elaine E. Tseng, Edgardo Alonso
Publikováno v:
Circulation. 142
Introduction: The Ross procedure is an excellent option for children and young adults who need aortic valve replacement as this surgery can restore patient survival to that of a normal sex and aged-matched population. However, some patients experienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88f62b74a79138126fef4a3a7be3ddc4
https://doi.org/10.1161/circ.142.suppl_3.16230
https://doi.org/10.1161/circ.142.suppl_3.16230
Autor:
Rosaire Mongrain, Richard L. Leask, Kevin Lachapelle, Mansour AlOmran, J. Garcia, Alexander Emmott
Publikováno v:
Journal of Surgical Simulation. 5:87-98
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27844bad9bd4ed4c281d58744d3cd38e
https://doi.org/10.1102/2051-7726.2018.0013
https://doi.org/10.1102/2051-7726.2018.0013
Publikováno v:
Cardiovascular Pathology. 29:48-52
Type A aortic dissection is an acute condition that requires urgent surgical intervention. However, in a subset of patients, aortic dissections go undiagnosed and become chronic, thereby allowing the dissected wall to undergo a distinct remodeling pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b69a2378a173a875dec0bd614c59b85
https://doi.org/10.1016/j.carpath.2017.05.006
https://doi.org/10.1016/j.carpath.2017.05.006
Autor:
Jennifer Chung, Vynka Lash, Mohammed Alreshidan, Richard L. Leask, Kevin Lachapelle, Alexander Emmott, Nastaran Shahmansouri
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 153:781-788
Introduction Ex vivo measurement of ascending aortic biomechanical properties may help understand the risk for rupture or dissection of dilated ascending aortas. A validated in vivo method that can predict aortic biomechanics does not exist. Speckle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fcb0e522e57a7bdc6debbf2ae1de32b
https://doi.org/10.1016/j.jtcvs.2016.11.056
https://doi.org/10.1016/j.jtcvs.2016.11.056
Autor:
Mohammed Alreshidan, Rosaire Mongrain, Kevin Lachapelle, Alexander Emmott, Richard L. Leask, Nastaran Shahmansouri, Raymond Cartier
Publikováno v:
Journal of the Mechanical Behavior of Biomedical Materials. 64:262-271
Ascending thoracic aortic aneurysms (ATAAs) can lead to a dissection or rupture of the aorta, causing death or disability of the patients. Surgical interventions used to treat this disease are associated with risks of mortality and morbidity. Several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88393ce1160aa05b3d0793be9e740315
https://doi.org/10.1016/j.jmbbm.2016.08.006
https://doi.org/10.1016/j.jmbbm.2016.08.006