Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Alexander E. Yueh"'
Autor:
Dustin A. Deming, Richard B. Halberg, Kristina A. Matkowskyj, Cheri A. Pasch, Linda Clipson, Dawn M. Albrecht, Alexander R. Schwartz, Alexander E. Yueh, Susan N. Payne, Molly E. Maher, Terrah J. Paul Olson, Alyssa A. Leystra, Jamie N. Hadac
Colonoscopic images over time, whole mount image and H&E-stained section of a tumor from a Apcfl/fl Pik3cap110* mouse inoculated with Adeno-Cre that spontaneously decreased in size.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c12dd3f9a1af0205ef1117b30e188d
https://doi.org/10.1158/1940-6207.22526871
https://doi.org/10.1158/1940-6207.22526871
Supplementary Figure S1 from MTORC1/2 Inhibition as a Therapeutic Strategy for PIK3CA Mutant Cancers
Autor:
Dustin A. Deming, Melissa C. Skala, Michael A. Newton, Kristina A. Matkowskyj, Paraic A. Kenny, Benjamin M. Parsons, Kayla K. Lemmon, Mark E. Burkard, Linda Clipson, Rebecca A. DeStefanis, Gioia Chengcheng Sha, Demetra P. Korkos, Mitchell G. Depke, Dana R. Van De Hey, Alexander E. Yueh, Tyler M. Foley, Cheri A. Pasch, Jeremy D. Kratz, Peter F. Favreau, Susan N. Payne, Stephanie L. Fricke
Supplementary Figure S1 presents the viability of SW48 and SW48PK cells after treatment with BEZ235 and TAK-228 at the 100-400nM concentrations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3797d51c82d44138bbd5766b7be6a207
https://doi.org/10.1158/1535-7163.22507717.v1
https://doi.org/10.1158/1535-7163.22507717.v1
Autor:
Dustin A. Deming, Richard B. Halberg, Kristina A. Matkowskyj, Cheri A. Pasch, Linda Clipson, Dawn M. Albrecht, Alexander R. Schwartz, Alexander E. Yueh, Susan N. Payne, Molly E. Maher, Terrah J. Paul Olson, Alyssa A. Leystra, Jamie N. Hadac
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abe99044f3aaee1458db8643cde6a30
https://doi.org/10.1158/1940-6207.22526880
https://doi.org/10.1158/1940-6207.22526880
Autor:
Dustin A. Deming, Melissa C. Skala, Michael A. Newton, Kristina A. Matkowskyj, Paraic A. Kenny, Benjamin M. Parsons, Kayla K. Lemmon, Mark E. Burkard, Linda Clipson, Rebecca A. DeStefanis, Gioia Chengcheng Sha, Demetra P. Korkos, Mitchell G. Depke, Dana R. Van De Hey, Alexander E. Yueh, Tyler M. Foley, Cheri A. Pasch, Jeremy D. Kratz, Peter F. Favreau, Susan N. Payne, Stephanie L. Fricke
PIK3CA mutations are common in clinical molecular profiling, yet an effective means to target these cancers has yet to be developed. MTORC1 inhibitors are often used off-label for patients with PIK3CA mutant cancers with only limited data to support
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61eef4938e53e1487200610ced459f4f
https://doi.org/10.1158/1535-7163.c.6538765.v1
https://doi.org/10.1158/1535-7163.c.6538765.v1
Autor:
Dustin A. Deming, Richard B. Halberg, Kristina A. Matkowskyj, Cheri A. Pasch, Linda Clipson, Dawn M. Albrecht, Alexander R. Schwartz, Alexander E. Yueh, Susan N. Payne, Molly E. Maher, Terrah J. Paul Olson, Alyssa A. Leystra, Jamie N. Hadac
Human colorectal cancers often possess multiple mutations, including three to six driver mutations per tumor. The timing of when these mutations occur during tumor development and progression continues to be debated. More advanced lesions carry a gre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607dda6918d6a664653ae51d904446df
https://doi.org/10.1158/1940-6207.c.6545235.v1
https://doi.org/10.1158/1940-6207.c.6545235.v1
Autor:
Dustin A. Deming, Richard B. Halberg, Kristina A. Matkowskyj, Cheri A. Pasch, Linda Clipson, Dawn M. Albrecht, Alexander R. Schwartz, Alexander E. Yueh, Susan N. Payne, Molly E. Maher, Terrah J. Paul Olson, Alyssa A. Leystra, Jamie N. Hadac
Characteristics of the mice treated with Adeno-Cre.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4038567713c28ee865be39e711256360
https://doi.org/10.1158/1940-6207.22526868.v1
https://doi.org/10.1158/1940-6207.22526868.v1
Autor:
Dustin A. Deming, Melissa C. Skala, Randall J. Kimple, Michael F. Bassetti, Irene M. Ong, Michael A. Newton, Kristina A. Matkowskyj, Kayla K. Lemmon, Mark E. Burkard, Evie H. Carchman, Devon Miller, Christine M. Walsh, Linda Clipson, Demetra P. Korkos, Susan N. Payne, Rosabella T. Pitera, Rebecca A. DeStefanis, Philip B. Emmerich, Carley M. Sprackling, Alyssa K. DeZeeuw, Kwangok P. Nickel, Mohammad Rezaul Karim, Joe T. Sharick, Amani A. Gillette, Christopher P. Babiarz, Alexander E. Yueh, Peter F. Favreau, Cheri A. Pasch
Dot plots corresponding to population distribution curves and graphs of individual replicates for bar graphs in Figure 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7330c7bce5376c4f183eb6067b2815ec
https://doi.org/10.1158/1078-0432.22469583
https://doi.org/10.1158/1078-0432.22469583
Autor:
Dustin A. Deming, Melissa C. Skala, Randall J. Kimple, Michael F. Bassetti, Irene M. Ong, Michael A. Newton, Kristina A. Matkowskyj, Kayla K. Lemmon, Mark E. Burkard, Evie H. Carchman, Devon Miller, Christine M. Walsh, Linda Clipson, Demetra P. Korkos, Susan N. Payne, Rosabella T. Pitera, Rebecca A. DeStefanis, Philip B. Emmerich, Carley M. Sprackling, Alyssa K. DeZeeuw, Kwangok P. Nickel, Mohammad Rezaul Karim, Joe T. Sharick, Amani A. Gillette, Christopher P. Babiarz, Alexander E. Yueh, Peter F. Favreau, Cheri A. Pasch
Purpose:Cancer treatment is limited by inaccurate predictors of patient-specific therapeutic response. Therefore, some patients are exposed to unnecessary side effects and delays in starting effective therapy. A clinical tool that predicts treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc31f39d9132103e6f6e0d614838406
https://doi.org/10.1158/1078-0432.c.6527292.v1
https://doi.org/10.1158/1078-0432.c.6527292.v1
Autor:
Dustin A. Deming, Melissa C. Skala, Randall J. Kimple, Michael F. Bassetti, Irene M. Ong, Michael A. Newton, Kristina A. Matkowskyj, Kayla K. Lemmon, Mark E. Burkard, Evie H. Carchman, Devon Miller, Christine M. Walsh, Linda Clipson, Demetra P. Korkos, Susan N. Payne, Rosabella T. Pitera, Rebecca A. DeStefanis, Philip B. Emmerich, Carley M. Sprackling, Alyssa K. DeZeeuw, Kwangok P. Nickel, Mohammad Rezaul Karim, Joe T. Sharick, Amani A. Gillette, Christopher P. Babiarz, Alexander E. Yueh, Peter F. Favreau, Cheri A. Pasch
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a9f8e60a6ce76e9a5440e0c2b3b870
https://doi.org/10.1158/1078-0432.22469568.v1
https://doi.org/10.1158/1078-0432.22469568.v1
Autor:
Dustin A. Deming, Melissa C. Skala, Randall J. Kimple, Michael F. Bassetti, Irene M. Ong, Michael A. Newton, Kristina A. Matkowskyj, Kayla K. Lemmon, Mark E. Burkard, Evie H. Carchman, Devon Miller, Christine M. Walsh, Linda Clipson, Demetra P. Korkos, Susan N. Payne, Rosabella T. Pitera, Rebecca A. DeStefanis, Philip B. Emmerich, Carley M. Sprackling, Alyssa K. DeZeeuw, Kwangok P. Nickel, Mohammad Rezaul Karim, Joe T. Sharick, Amani A. Gillette, Christopher P. Babiarz, Alexander E. Yueh, Peter F. Favreau, Cheri A. Pasch
Success rates for growing human cancers in spheroid culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ebdc403191475e5e340316a507abb58
https://doi.org/10.1158/1078-0432.22469565
https://doi.org/10.1158/1078-0432.22469565