Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alexander E. P. Loftus"'
Autor:
Frederic Li Mow Chee, Bruno Beernaert, Billie G. C. Griffith, Alexander E. P. Loftus, Yatendra Kumar, Jimi C. Wills, Martin Lee, Jessica Valli, Ann P. Wheeler, J. Douglas Armstrong, Maddy Parsons, Irene M. Leigh, Charlotte M. Proby, Alex von Kriegsheim, Wendy A. Bickmore, Margaret C. Frame, Adam Byron
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Cells transmit mechanical force to the nucleus via the cytoskeleton. Here, the authors reveal a role for the actin regulator Mena in force transmission at the nuclear envelope, where it regulates nuclear architecture, chromatin organization and gene
Externí odkaz:
https://doaj.org/article/c362f4cc95db4024a0d3eb4b310fffac
Autor:
Adam Byron, Billie G. C. Griffith, Ana Herrero, Alexander E. P. Loftus, Emma S. Koeleman, Linda Kogerman, John C. Dawson, Niamh McGivern, Jayne Culley, Graeme R. Grimes, Bryan Serrels, Alex von Kriegsheim, Valerie G. Brunton, Margaret C. Frame
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Cell adhesion proteins have been described at sites away from the cell surface, including in the nucleus. Here, the authors report the scale of nuclear localisation of adhesion proteins, establishing a nucleo-adhesome and showing that nuclear adhesio
Externí odkaz:
https://doaj.org/article/83349dab846e4f55a388ec199c877673
Autor:
Adam Byron, Billie G. C. Griffith, Ana Herrero, Alexander E. P. Loftus, Emma S. Koeleman, Linda Kogerman, John C. Dawson, Niamh McGivern, Jayne Culley, Graeme R. Grimes, Bryan Serrels, Alex von Kriegsheim, Valerie G. Brunton, Margaret C. Frame
Publikováno v:
Byron, A, Griffith, B G C, Herrero, A, Loftus, A E P, Koeleman, E S, Kogerman, L, Dawson, J C, McGivern, N, Culley, J, Grimes, G R, Serrels, B, Kriegsheim, A V, Brunton, V G & Frame, M C 2022, ' Characterisation of a nucleo-adhesome ', Nature Communications, vol. 13, no. 1, 3053 . https://doi.org/10.1038/s41467-022-30556-5
Byron, A, Griffith, B, Herrero Mier, A, Loftus, A E P, Koeleman, E S, Kogerman, L, Dawson, J C, McGivern, N, Culley, J, Grimes, G R, Serrels, B, von Kriegsheim, A, Brunton, V G & Frame, M C 2022, ' Characterisation of a nucleo-adhesome ', Nature Communications . https://doi.org/10.1038/s41467-022-30556-5
Byron, A, Griffith, B, Herrero Mier, A, Loftus, A E P, Koeleman, E S, Kogerman, L, Dawson, J C, McGivern, N, Culley, J, Grimes, G R, Serrels, B, von Kriegsheim, A, Brunton, V G & Frame, M C 2022, ' Characterisation of a nucleo-adhesome ', Nature Communications . https://doi.org/10.1038/s41467-022-30556-5
In addition to central functions in cell adhesion signalling, integrin-associated proteins have wider roles at sites distal to adhesion receptors. In experimentally defined adhesomes, we noticed that there is clear enrichment of proteins that localis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880df6d692ea82748eb2741b6d3df01e
https://pubmed.ncbi.nlm.nih.gov/35650196
https://pubmed.ncbi.nlm.nih.gov/35650196