Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Alexander E. Kel"'
Autor:
Alexander E. Kel
Publikováno v:
Data in Brief, Vol 10, Iss C, Pp 499-504 (2017)
Computational analysis of master regulators through the search for transcription factor binding sites followed by analysis of signal transduction networks of a cell is a new approach of causal analysis of multi-omics data. This paper contains results
Externí odkaz:
https://doaj.org/article/c8243fce6e0d4708b335c66614154af5
Autor:
Mariya A. Smetanina, Valeria A. Korolenya, Alexander E. Kel, Ksenia S. Sevostyanova, Konstantin A. Gavrilov, Andrey I. Shevela, Maxim L. Filipenko
Publikováno v:
Epigenomes; Volume 7; Issue 1; Pages: 8
Epigenomic changes in the venous cells exerted by oscillatory shear stress towards the endothelium may result in consolidation of gene expression alterations upon vein wall remodeling during varicose transformation. We aimed to reveal such epigenome-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd52cd4f3a742625b108a8137e37b70c
https://doi.org/10.3390/epigenomes7010008
https://doi.org/10.3390/epigenomes7010008
Autor:
D. V. Maltseva, Oscar E. Simonson, J. Carlos Villaescusa, Noah Moruzzi, Roman A. Zubarev, Magnus Nordenskjöld, Alexander G. Tonevitsky, Amir Ata Saei, Massimiliano Gaetani, Mike Aoun, Niels Leijten, Kamilya Altynbekova, Vincent Millischer, Rikard Holmdahl, Per Olof Berggren, Pierre Sabatier, Karl-Henrik Grinnemo, Alexander E. Kel, Ana Coelho, Sandeep Kadekar, Sergey Rodin, Christian M. Beusch, Patrick Micke
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Detailed characterization of cell type transitions is essential for cell biology in general and particularly for the development of stem cell-based therapies in regenerative medicine. To systematically study such transitions, we introduce a method th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53699eab999c9c3a454543eb2a71c17
http://europepmc.org/articles/PMC8590018
http://europepmc.org/articles/PMC8590018
Publikováno v:
Virus Bioinformatics ISBN: 9781003097679
Virus Bioinformatics
Virus Bioinformatics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c62e0cb7afaa69e666db7dc4159e1fb
https://doi.org/10.1201/9781003097679-11
https://doi.org/10.1201/9781003097679-11
Autor:
Nariman F. Salakhutdinov, Evgeniya B. Logashenko, Marina A. Zenkova, Andrey V. Markov, Alexander E. Kel, Oksana V. Salomatina
Publikováno v:
Oncotarget
Semisynthetic triterpenoids, bearing cyano enone functionality in ring A, are considered now as novel promising anti-tumor agents. However, despite the large-scale studies, their effects on cervical carcinoma cells and, moreover, mechanisms underlyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927feb954aebfd5c714896e308cd6ca1
http://europepmc.org/articles/PMC6731101
http://europepmc.org/articles/PMC6731101
Autor:
Elena Kutumova, Yury V. Kondrakhin, Ilya R. Akberdin, Alexander E. Kel, Ivan S. Yevshin, llya Kiselev, Semyon K. Kolmykov, Fedor A. Kolpakov, Anna S. Ryabova, S. S. Pintus, Nikita Mandrik, Ruslan N. Sharipov, Timur A. Kashapov
Publikováno v:
Nucleic Acids Research
BioUML (homepage: http://www.biouml.org, main public server: https://ict.biouml.org) is a web-based integrated environment (platform) for systems biology and the analysis of biomedical data generated by omics technologies. The BioUML vision is to pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d14e76ea5c323c839873e678e8cb0c
http://europepmc.org/articles/PMC6602424
http://europepmc.org/articles/PMC6602424
Walking pathways with positive feedback loops reveal DNA methylation biomarkers of colorectal cancer
Autor:
Leonid S. Leskov, Alexander E. Kel, Manel Esteller, Olga V. Kel-Margoulis, Ulyana A. Boyarskikh, Sebastian Moran, Philip Stegmaier, Daria Stelmashenko, Anna Martínez-Cardús, Nikita Mandrik, Jeannette Koschmann, Edgar Wingender, Andrey Sokolov, Fedor A. Kolpakov, Ivan S. Yevshin, Mathias Krull, Maxim L. Filipenko
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S4, Pp 1-20 (2019)
BMC Bioinformatics
BMC Bioinformatics
Background The search for molecular biomarkers of early-onset colorectal cancer (CRC) is an important but still quite challenging and unsolved task. Detection of CpG methylation in human DNA obtained from blood or stool has been proposed as a promisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d42cc2870eb3549008c9452f0b637c
http://link.springer.com/article/10.1186/s12859-019-2687-7
http://link.springer.com/article/10.1186/s12859-019-2687-7
Autor:
Alexander E. Kel, Ivan V. Kulakovskiy, Ruslan N. Sharipov, Ivan S. Yevshin, Yury V. Kondrakhin, Mikhail A. Kulyashov, Semyon K. Kolmykov, Fedor A. Kolpakov, Vsevolod J. Makeev
Publikováno v:
Nucleic Acids Research
The Gene Transcription Regulation Database (GTRD; http://gtrd.biouml.org/) contains uniformly annotated and processed NGS data related to gene transcription regulation: ChIP-seq, ChIP-exo, DNase-seq, MNase-seq, ATAC-seq and RNA-seq. With the latest r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5544d1903fcc92ade7012156cba8df
https://pubmed.ncbi.nlm.nih.gov/33231677
https://pubmed.ncbi.nlm.nih.gov/33231677
Only 2% of Glioblastoma multiforme (GBM) patients respond to standard care and survive beyond 36 months (long-term survivors, LTS) while the majority survives less than 12 months (short-term survivors, STS). To understand the mechanism leading to poo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b0f92f2b02529b95538501d71fc9f9
https://doi.org/10.20944/preprints202010.0046.v1
https://doi.org/10.20944/preprints202010.0046.v1
Autor:
Alexei Gratchev, Nikita G. Nikiforov, S. S. Pintus, Kathy K Foxx, Alexandra A. Melnichenko, Vasily N. Sukhorukov, Volha I Summerhill, Daria Stelmashenko, Wei-Kai Wu, Philip Stegmaier, Yumiko Oishi, Alexander E. Kel, Igor A. Sobenin, Marina V. Kubekina, Alexander N. Orekhov, Ichiro Manabe, Reinhard Wetzker
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3, p 817 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 3, p 817 (2020)
Excessive accumulation of lipid inclusions in the arterial wall cells (foam cell formation) caused by modified low-density lipoprotein (LDL) is the earliest and most noticeable manifestation of atherosclerosis. The mechanisms of foam cell formation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a221f693fa2dc7c10addd716ebf342
http://europepmc.org/articles/PMC7037225
http://europepmc.org/articles/PMC7037225