Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Alexander E Kabakov"'
Autor:
Vladimir A Kudryavtsev, Anna V Khokhlova, Vera A Mosina, Elena I Selivanova, Alexander E Kabakov
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173640 (2017)
We studied a role of the inducible heat shock protein 70 (Hsp70) in cellular response to radiosensitizing treatments with inhibitors of the heat shock protein 90 (Hsp90) chaperone activity. Cell lines derived from solid tumors of different origin wer
Externí odkaz:
https://doaj.org/article/c69150df6b7942b0bfc8b62f7c395350
Publikováno v:
Cells
Cells, Vol 10, Iss 3446, p 3446 (2021)
Cells, Vol 10, Iss 3446, p 3446 (2021)
The high frequency of breast cancer worldwide and the high mortality among women with this malignancy are a serious challenge for modern medicine. A deeper understanding of the mechanisms of carcinogenesis and emergence of metastatic, therapy-resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1072528dd27461f634d1b3b8703ce0
https://pubmed.ncbi.nlm.nih.gov/34943954
https://pubmed.ncbi.nlm.nih.gov/34943954
Autor:
Anna O Yakimova, Alexander E Kabakov
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1102, p 1102 (2021)
Cancers, Vol 13, Iss 1102, p 1102 (2021)
Simple Summary Some regions of aggressive malignancies experience hypoxia due to inadequate blood supply. Cancer cells adapting to hypoxic conditions somehow become more resistant to radiation exposure and this decreases the efficacy of radiotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a05492459902a1c862e775c23adae94
https://pubmed.ncbi.nlm.nih.gov/33806538
https://pubmed.ncbi.nlm.nih.gov/33806538
Publikováno v:
Cells
Cells, Vol 9, Iss 892, p 892 (2020)
Cells, Vol 9, Iss 892, p 892 (2020)
Cancer stem cells (CSCs) are a great challenge in the fight against cancer because these self-renewing tumorigenic cell fractions are thought to be responsible for metastasis dissemination and cases of tumor recurrence. In comparison with non-stem ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a767ff83a22ce3f4ac54e304fb560699
https://pubmed.ncbi.nlm.nih.gov/32268506
https://pubmed.ncbi.nlm.nih.gov/32268506
Publikováno v:
"Radiation and Risk" Bulletin of the National Radiation and Epidemiological Registry. 27:62-75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19eea50635a59829d46c71ae45198ed1
https://doi.org/10.21870/0131-3878-2018-27-2-62-75
https://doi.org/10.21870/0131-3878-2018-27-2-62-75
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO3-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7b6df3d38a204110257335d19e14610
https://doi.org/10.1254/jpssuppl.wcp2018.0_po3-7-23
https://doi.org/10.1254/jpssuppl.wcp2018.0_po3-7-23
Publikováno v:
Methods in Molecular Biology ISBN: 9781493974764
Heat shock proteins are well-known protectors from cell death. Cell death (in particular, apoptosis and necrosis) is accompanied by certain hallmarks manifested as specific alterations in cellular membranes, cytoplasm, nucleus, and mitochondria. Some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07b39d8658bbc8a0c4bdf6e3d56a2e7e
https://doi.org/10.1007/978-1-4939-7477-1_9
https://doi.org/10.1007/978-1-4939-7477-1_9
Autor:
Vera A. Mosina, Elena I. Selivanova, Vladimir A. Kudryavtsev, Anna V. Khokhlova, Alexander E. Kabakov
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173640 (2017)
PLoS ONE
PLoS ONE
We studied a role of the inducible heat shock protein 70 (Hsp70) in cellular response to radiosensitizing treatments with inhibitors of the heat shock protein 90 (Hsp90) chaperone activity. Cell lines derived from solid tumors of different origin wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82554c9f4cfb572b3c4fda1eaa8668fe
http://europepmc.org/articles/PMC5349677?pdf=render
http://europepmc.org/articles/PMC5349677?pdf=render
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 6:61-67
Effects of inhibitors of the heat shock protein 90 (HSP90) chaperone activity and inhibitors of the heat shock protein (HSP) expression on sensitivity of HeLa tumor cells to hyperthermia were studied. It was found that nanomolar concentrations of inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5feb51264491d5aac7e5edea209272cf
https://doi.org/10.1134/s1990750812010088
https://doi.org/10.1134/s1990750812010088
Publikováno v:
Biophysics. 56:339-345
The 90-kDa heat shock protein (Hsp90) is one of the major chaperones in eukaryotes and catalyzes the maturation and activation of its client proteins. Oncogene products, hormones or growth factor receptors, and key components of signaling pathways ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f554db96baf5a4e35158bf2f692e9d5
https://doi.org/10.1134/s0006350911020126
https://doi.org/10.1134/s0006350911020126