Zobrazeno 1 - 10
of 516
pro vyhledávání: '"Alexander Drzezga"'
Autor:
Verena Dzialas, Merle C. Hoenig, Stéphane Prange, Gérard N. Bischof, the Parkinson’s Progression Marker Initiative, Alexander Drzezga, Thilo van Eimeren
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Resilience in neuroscience generally refers to an individual’s capacity to counteract the adverse effects of a neuropathological condition. While resilience mechanisms in Alzheimer’s disease are well-investigated, knowledge regarding its
Externí odkaz:
https://doaj.org/article/6670e329cb2c466388f32386778e75eb
Autor:
Simone Wegen, Karina Claus, Philipp Linde, Johannes Rosenbrock, Maike Trommer, Thomas Zander, Armin Tuchscherer, Christiane Bruns, Hans Anton Schlößer, Wolfgang Schröder, Marie-Lisa Eich, Thomas Fischer, Klaus Schomäcker, Alexander Drzezga, Carsten Kobe, Katrin Sabine Roth, Jasmin Josefine Weindler
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Fibroblast activation protein (FAP) is expressed in the tumor microenvironment (TME) of various cancers. In our analysis, we describe the impact of dual-tracer imaging with Gallium-68-radiolabeled inhibitors of FAP (FAPI-46-PET/CT
Externí odkaz:
https://doaj.org/article/ce5d14ae5759413998c9bebf6d8a92b5
Autor:
Ali Gordji-Nejad, Andreas Matusch, Sophie Kleedörfer, Harshal Jayeshkumar Patel, Alexander Drzezga, David Elmenhorst, Ferdinand Binkofski, Andreas Bauer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The inverse effects of creatine supplementation and sleep deprivation on high energy phosphates, neural creatine, and cognitive performances suggest that creatine is a suitable candidate for reducing the negative effects of sleep deprivation
Externí odkaz:
https://doaj.org/article/17bf3082cd834a9b89ddb6889866f279
Autor:
Hendrik Theis, Stéphane Prange, Gérard N. Bischof, Merle C. Hoenig, Marc Tittgemeyer, Lars Timmermann, Gereon R. Fink, Alexander Drzezga, Carsten Eggers, Thilo van Eimeren
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-7 (2023)
Abstract Impulsive-compulsive behaviour (ICB) is a frequently observed non-motor symptom in early Parkinson’s disease after initiating dopamine replacement therapy. At the opposite end of the motivated behaviour spectrum, apathy occurs in early Par
Externí odkaz:
https://doaj.org/article/d8b9f2365bfd433eb5435de244ce6a9f
Autor:
Jan Heilinger, Jasmin Weindler, Katrin Sabine Roth, Philipp Krapf, Klaus Schomäcker, Markus Dietlein, Alexander Drzezga, Carsten Kobe
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Background In 2022, the American Food and Drug Administration and the European Medicines Agency approved [177Lu]Lu-PSMA-617 (PLUVICTO™, Novartis AG, Basel, Switzerland) for radionuclide therapy with prostate-specific membrane antigen (PSMA
Externí odkaz:
https://doaj.org/article/638c38dfd2874b4eafd1d9ad3f555c00
Autor:
Marina C. Ruppert-Junck, Gunter Kräling, Andrea Greuel, Marc Tittgemeyer, Lars Timmermann, Alexander Drzezga, Carsten Eggers, David Pedrosa
Publikováno v:
Frontiers in Computational Neuroscience, Vol 18 (2024)
Parkinson's disease (PD) is currently diagnosed largely on the basis of expert judgement with neuroimaging serving only as a supportive tool. In a recent study, we identified a hypometabolic midbrain cluster, which includes parts of the substantia ni
Externí odkaz:
https://doaj.org/article/70efd511948d4301be4f0e0c5c3243de
Autor:
Klaus Schomäcker, Felix Dietlein, Sergio Muñoz Vázquez, Feodor Braun, Thomas Fischer, Philipp Krapf, Alexander Drzezga, Markus Dietlein
Publikováno v:
Molecules, Vol 29, Iss 1, p 185 (2023)
The interdisciplinary possibilities inherent in nuclear medicine offer an opportunity for the patient-centered development of radioactive pharmaceuticals based on specific research questions. This approach provides radiopharmaceutical manufacturers w
Externí odkaz:
https://doaj.org/article/0127700093844dd8ab1582489d9572f0
Autor:
Kenan Steidel, Marina C. Ruppert, Andrea Greuel, Masoud Tahmasian, Franziska Maier, Jochen Hammes, Thilo van Eimeren, Lars Timmermann, Marc Tittgemeyer, Alexander Drzezga, David J. Pedrosa, Carsten Eggers
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract The prevailing network perspective of Parkinson’s disease (PD) emerges not least from the ascending neuropathology traceable in histological studies. However, whether longitudinal in vivo correlates of network degeneration in PD can be obs
Externí odkaz:
https://doaj.org/article/4d234eb6376f41a088bf43bcbd4572ba
Autor:
Lyduine E. Collij, Gill Farrar, David Valléz García, Ilona Bader, Mahnaz Shekari, Luigi Lorenzini, Hugh Pemberton, Daniele Altomare, Sandra Pla, Mery Loor, Pawel Markiewicz, Maqsood Yaqub, Christopher Buckley, Giovanni B. Frisoni, Agneta Nordberg, Pierre Payoux, Andrew Stephens, Rossella Gismondi, Pieter Jelle Visser, Lisa Ford, Mark Schmidt, Cindy Birck, Jean Georges, Anja Mett, Zuzana Walker, Mercé Boada, Alexander Drzezga, Rik Vandenberghe, Bernard Hanseeuw, Frank Jessen, Michael Schöll, Craig Ritchie, Isadora Lopes Alves, Juan Domingo Gispert, Frederik Barkhof
Publikováno v:
Frontiers in Neurology, Vol 13 (2023)
BackgroundAmyloid-β (Aβ) accumulation is considered the earliest pathological change in Alzheimer's disease (AD). The Amyloid Imaging to Prevent Alzheimer's Disease (AMYPAD) consortium is a collaborative European framework across European Federatio
Externí odkaz:
https://doaj.org/article/e7fa1233238f47be9c405a3b15ff6cf3
Autor:
Marta Anglada-Huguet, Heike Endepols, Astrid Sydow, Ronja Hilgers, Bernd Neumaier, Alexander Drzezga, Senthilvelrajan Kaniyappan, Eckhard Mandelkow, Eva-Maria Mandelkow
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9260 (2023)
The accumulation of tau is a hallmark of several neurodegenerative diseases and is associated with neuronal hypoactivity and presynaptic dysfunction. Oral administration of the adenosine A1 receptor antagonist rolofylline (KW-3902) has previously bee
Externí odkaz:
https://doaj.org/article/f7689011d3ea494bb8fb474c918feb55