Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alexander Dohnal"'
Autor:
Vanessa Monteil, Brett Eaton, Elena Postnikova, Michael Murphy, Benedict Braunsfeld, Ian Crozier, Franz Kricek, Janine Niederhöfer, Alice Schwarzböck, Helene Breid, Stephanie Devignot, Jonas Klingström, Charlotte Thålin, Max J Kellner, Wanda Christ, Sebastian Havervall, Stefan Mereiter, Sylvia Knapp, Anna Sanchez Jimenez, Agnes Bugajska‐Schretter, Alexander Dohnal, Christine Ruf, Romana Gugenberger, Astrid Hagelkruys, Nuria Montserrat, Ivona Kozieradzki, Omar Hasan Ali, Johannes Stadlmann, Michael R Holbrook, Connie Schmaljohn, Chris Oostenbrink, Robert H Shoemaker, Ali Mirazimi, Gerald Wirnsberger, Josef M Penninger
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 8, Pp n/a-n/a (2022)
Abstract The recent emergence of multiple SARS‐CoV‐2 variants has caused considerable concern due to both reduced vaccine efficacy and escape from neutralizing antibody therapeutics. It is, therefore, paramount to develop therapeutic strategies t
Externí odkaz:
https://doaj.org/article/8b99883b78934b478c6d1c13c62796ff
Autor:
Katrin Meissl, Natalija Simonović, Lena Amenitsch, Agnieszka Witalisz-Siepracka, Klara Klein, Caroline Lassnig, Ana Puga, Claus Vogl, Andrea Poelzl, Markus Bosmann, Alexander Dohnal, Veronika Sexl, Mathias Müller, Birgit Strobl
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Natural killer (NK) cells are important components of the innate immune defense against infections and cancers. Signal transducer and activator of transcription 1 (STAT1) is a transcription factor that is essential for NK cell maturation and NK cell-
Externí odkaz:
https://doaj.org/article/66b5c411e76242849b6bb7f69d378e49
Autor:
Agnieszka Witalisz-Siepracka, Klara Klein, Daniela Prinz, Nicoletta Leidenfrost, Gernot Schabbauer, Alexander Dohnal, Veronika Sexl
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
The Janus kinase—signal transducers and activators of transcription (JAK-STAT) signaling pathway is critical in tuning immune responses and its dysregulation is tightly associated with cancer and immune disorders. Disruption of interleukin (IL)-15/
Externí odkaz:
https://doaj.org/article/2f951d23eda3495eb28242143f879da0
Autor:
Johanna Eder, Radu Rogojanu, Waltraud Jerney, Friedrich Erhart, Alexander Dohnal, Melitta Kitzwögerer, Georg Steiner, Julia Moser, Franz Trautinger
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0163661 (2016)
Mast cells (MC) are bone marrow derived haematopoetic cells playing a crucial role not only in immune response but also in the tumor microenvironment with protumorigenic and antitumorigenic functions. The role of MC in primary cutaneous T-cell lympho
Externí odkaz:
https://doaj.org/article/4ea99a1973854cfdb1b1462da3bcad7a
Autor:
Romana Gugenberger, Alexander Dohnal, Kathrin Thell, Sarah Bischof, Mario Kuttke, Bernhard Peball, Hannes Muehleisen, Maria Urban, Andreas Tanzmann, Beate Pribitzer, Felix Batrina, Stefan Bunka, Sophia Spagl, Manuela Branka, Markus Raderer, Gerald Prager, Thorsten Fuereder, Nina Worel
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Romana Gugenberger, Alexander Dohnal, Andreas Tanzmann, Beate Pribitzer, Felix Batrina, Stefan Bunka, Sophia Spagl, Manuela Branka, Sarah Bischof, Kathrin Thell, Mario Kuttke, Maria Urban, Hannes Muehleisen, Bernhard Peball, Markus Raderer, Gerald Prager, Nina Worel
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Jakob Berner, Tamara Weiss, Helena Sorger, Fikret Rifatbegovic, Max Kauer, Reinhard Windhager, Alexander Dohnal, Peter F. Ambros, Inge M. Ambros, Kaan Boztug, Peter Steinberger, Sabine Taschner‐Mandl
Publikováno v:
GliaREFERENCES. 70(12)
The plastic potential of Schwann cells (SCs) is increasingly recognized to play a role after nerve injury and in diseases of the peripheral nervous system. Reports on the interaction between immune cells and SCs indicate their involvement in inflamma
Autor:
Mario Kuttke, Alexander Dohnal, Andreas Tanzmann, Beate Pribitzer, Felix Batrina, Stefan Bunka, Sophia Spagl, Manuela Branka, Sarah Bischof, Kathrin Thell, Maria Urban, Hannes Muehleisen, Bernhard Peball, Bianca Gapp, Angela Halfmann, Markus Raderer, Gerald Prager, Thorsten Fuereder, Romana Gugenberger, Nina Worel
Publikováno v:
Cancer Research. 83:LB187-LB187
Immune checkpoint control is one of several mechanisms that negatively influence the immune system and contribute to the development and progression of cancer. To enhance anti-tumor immune responses in patients with advanced solid tumors, we employ a
Autor:
Andrea Vogel, Katharina Martin, Klara Soukup, Angela Halfmann, Martina Kerndl, Julia S. Brunner, Melanie Hofmann, Laura Oberbichler, Ana Korosec, Mario Kuttke, Hannes Datler, Markus Kieler, Laszlo Musiejovsky, Alexander Dohnal, Omar Sharif, Gernot Schabbauer
Publikováno v:
Cell reports. 38(8)
Dendritic cells (DCs) induce peripheral T cell tolerance, but cell-intrinsic signaling cascades governing their stable tolerogenesis remain poorly defined. Janus Kinase 1 (JAK1) transduces cytokine-receptor signaling, and JAK inhibitors (Jakinibs), i
Autor:
Hans Loibner, Kerstin Westritschnig, Oliver Mutschlechner, Marc Salzberg, Alexander Dohnal, Guenther Lametschwandtner, Pierre L. Triozzi
Publikováno v:
Journal of Clinical Oncology. 36:3055-3055
3055Background: Casitas-B-lineage lymphoma protein – b (cbl-b), an E3 ubiquitin ligase is an important intracellular checkpoint limiting activation of lymphocytes and NK cells. Silencing of cbl-b e...