Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Alexander Dietl"'
Autor:
Rebecca Schönmehl, Daniel H. Mendelsohn, Lina Winter, Steffen Pabel, Tanja Niedermair, Katja Evert, Wing-Hoi Cheung, Ronald Man Yeung Wong, Volker H. Schmitt, Karsten Keller, Friedrich Barsch, Alexander Dietl, Jan F. Gummert, René Schramm, Samuel Sossalla, Christoph Brochhausen
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7644 (2024)
Background: Mitochondria play a crucial role in adapting to fluctuating energy demands, particularly in various heart diseases. This study investigates mitochondrial morphology near intercalated discs in left ventricular (LV) heart tissues, comparing
Externí odkaz:
https://doaj.org/article/03b26e33f7474ec7b0672325fe2460dc
Autor:
Caroline Brandl, Martina E. Zimmermann, Felix Günther, Alexander Dietl, Helmut Küchenhoff, Julika Loss, Klaus J. Stark, Iris M. Heid
Publikováno v:
BMC Geriatrics, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background Containment measures in the COVID-19 pandemic protected individuals at high risk, particularly individuals at old age, but little is known about how these measures affected health-related behavior of old aged individuals. We aimed
Externí odkaz:
https://doaj.org/article/68f8e807fe5442c2b35c39fbd3908a6a
Autor:
Andreas Luchner, Ralph Burkhardt, Alexander Dietl, Martina E Zimmermann, Caroline Brandl, Stefan Wallner, Lars S Maier, Iris M Heid, Klaus J Stark
Publikováno v:
BMJ Open, Vol 11, Iss 11 (2021)
Objective European guidelines recommended a uniform upper reference limit of high-sensitivity cardiac troponin T (hsTnT) to rule out non-ST segment elevation myocardial infarction. Our study aimed to provide a hsTnT reference distribution and to asse
Externí odkaz:
https://doaj.org/article/21146b2946dd4fa8baddfc1c97dda276
Autor:
Alexander Dietl, Christine Prieschenk, Franziska Eckert, Christoph Birner, Andreas Luchner, Lars S. Maier, Stefan Buchner
Publikováno v:
Cardiovascular Ultrasound, Vol 16, Iss 1, Pp 1-10 (2018)
Abstract Background Percutaneous mitral valve repair (PMVR) is increasingly performed in patients with severe mitral regurgitation (MR). Post-procedural MR grading is challenging and an unsettled issue. We hypothesised that the direct planimetry of v
Externí odkaz:
https://doaj.org/article/90da0dd19e9f448d8d9bf9530eeffc4e
Autor:
Alexander Dietl, Ingrid Winkel, Gabriela Pietrzyk, Michael Paulus, Astrid Bruckmann, Josef A Schröder, Samuel Sossalla, Andreas Luchner, Lars S Maier, Christoph Birner
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0225937 (2019)
BACKGROUND:Heart failure induced cachexia is highly prevalent. Insights into disease progression are lacking. METHODS:Early state of left ventricular dysfunction (ELVD) and symptomatic systolic heart failure (HF) were both induced in rabbits by tachy
Externí odkaz:
https://doaj.org/article/000dca32c33848f89c2d0dabae323556
Autor:
Laura Grois, Julian Hupf, Jörg Reinders, Josef Schröder, Alexander Dietl, Peter M Schmid, Carsten Jungbauer, Markus Resch, Lars S Maier, Andreas Luchner, Christoph Birner
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169743 (2017)
BACKGROUND:Inhibitors of the renin angiotensin system and neprilysin (RAS-/NEP-inhibitors) proved to be extraordinarily beneficial in systolic heart failure. Furthermore, compelling evidence exists that impaired mitochondrial pathways are causatively
Externí odkaz:
https://doaj.org/article/24f3b406ac854ddf86e1c7db9c1de2ca
Autor:
Christoph Birner, Sarah Hierl, Alexander Dietl, Julian Hupf, Carsten Jungbauer, Peter M. Schmid, Petra Rümmele, Rainer Deutzmann, Günter Riegger, Andreas Luchner
Publikováno v:
Cellular Physiology and Biochemistry, Vol 33, Iss 3, Pp 692-704 (2014)
Background: Heart failure (CHF) is characterized by dyspnea and pulmonary changes. The underlying molecular adaptations are unclear, but might provide targets for therapeutic interventions. We therefore conceived a study to determine molecular change
Externí odkaz:
https://doaj.org/article/a88a9294db57452b8bdd2751cd5bf7ce
Autor:
Alexander Dietl, Klaus Stark, Martina E Zimmermann, Christa Meisinger, Heribert Schunkert, Christoph Birner, Lars S Maier, Annette Peters, Iris M Heid, Andreas Luchner
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164060 (2016)
AIMS:B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) predict cardiovascular endpoints in patients and all-cause death in the general population. This was assigned to their association with clinical cardiac remodelling defined as ch
Externí odkaz:
https://doaj.org/article/38d464c36a3d402dadcce729e81e0691
Autor:
Ferdinand J. Donhauser, Martina E. Zimmermann, Anna B. Steinkirchner, Simon Wiegrebe, Alexander Dietl, Caroline Brandl, Ralph Burkhardt, André Gessner, Frank Schweda, Tobias Bergler, Elke Schäffner, Carsten A. Böger, Florian Kronenberg, Andreas Luchner, Klaus J. Stark, Iris M. Heid
Publikováno v:
Journal of Clinical Medicine; Volume 12; Issue 6; Pages: 2102
Cardiovascular risk factors such as high glucose, LDL-cholesterol, blood pressure, and impaired kidney function are particularly frequent in old-aged individuals. However, population-based data on the extent of cardiovascular risk factor control in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fa244882c4ad377ee63574cb5a27bf
Autor:
Martina Krüger, Sebastian Kötter, Alexander Dietl, Andreas Unger, Alexander Nickel, Belal A. Mohamed, Lars I. Leichert, Christoph Maack, Christine M Loescher, Martin Breitkreuz, Andreas J. Schmidt, Yong Li, Karl Toischer, Nazha Hamdani, Wolfgang A. Linke, Joachim P. Schmitt, Marcus Krüger
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Titin oxidation alters titin stiffness, which greatly contributes to overall myocardial stiffness. This stiffness is frequently increased in heart disease, such as diastolic heart failure. We have quantified the degree of oxidative titin