Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alexander David Barrow"'
Publikováno v:
Pathogens, Vol 12, Iss 4, p 572 (2023)
Changes in the cellular secretome are implicated in virus infection, malignancy, and anti-tumor immunity. We analyzed the association between transcriptional signatures (TS) from 24 different immune and stromal cell types on the prognosis of HPV-infe
Externí odkaz:
https://doaj.org/article/c340eaa907214ed19109690ea4b6657a
Autor:
Yuhan Sun, Alexander James Sedgwick, Md Abdullah-Al-Kamran Khan, Yaseelan Palarasah, Stefano Mangiola, Alexander David Barrow
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Activation of natural killer (NK) cell function is regulated by cytokines, such as IL-2, and secreted factors upregulated in the tumor microenvironment, such as platelet-derived growth factor D (PDGF-DD). In order to elucidate a clinical role for the
Externí odkaz:
https://doaj.org/article/9a25b716f78e484a8ead390e5f420cf3
Autor:
Yuhan Sun, Alexander James Sedgwick, Yaseelan Palarasah, Stefano Mangiola, Alexander David Barrow
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The binding of platelet-derived growth factor D (PDGF-DD) to the NKp44 receptor activates a distinct transcriptional program in primary IL-2 expanded human natural killer (NK) cells. We were interested in knowing if the PDGF-DD-NKp44 pathway of NK ce
Externí odkaz:
https://doaj.org/article/6e5112c9b83a4515968760f3366f640e
Autor:
Alexander James Sedgwick, Nazanin Ghazanfari, Patrick Constantinescu, Theo Mantamadiotis, Alexander David Barrow
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The brain is considered an immune privileged site due to the high selectivity of the blood-brain barrier which restricts the passage of molecules and cells into the brain parenchyma. Recent studies have highlighted active immunosurveillance mechanism
Externí odkaz:
https://doaj.org/article/d42199bd215141b88981792bd9d86428
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The Natural Cytotoxicity Receptors (NCRs), NKp46, NKp44, and NKp30, were some of the first human activating Natural Killer (NK) cell receptors involved in the non-MHC-restricted recognition of tumor cells to be cloned over 20 years ago. Since this ti
Externí odkaz:
https://doaj.org/article/d0219a6c08fd4f50ae88c4166029d474
Autor:
Alexander David Barrow, John Trowsdale
Publikováno v:
European Journal of Immunology. 36:2276-2276
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1151aa2d80806438c683dc6dbc41287
https://doi.org/10.1002/eji.200690029
https://doi.org/10.1002/eji.200690029