Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alexander D. Jacob"'
Autor:
Lina M. Tran, Andrew J. Mocle, Adam I. Ramsaran, Alexander D. Jacob, Paul W. Frankland, Sheena A. Josselyn
Publikováno v:
Frontiers in Neural Circuits, Vol 14 (2020)
In vivo 1-photon (1p) calcium imaging is an increasingly prevalent method in behavioral neuroscience. Numerous analysis pipelines have been developed to improve the reliability and scalability of pre-processing and ROI extraction for these large calc
Externí odkaz:
https://doaj.org/article/e007498310e04931a0f0cf1a763b4490
Publikováno v:
Brain Res Bull
Memories of past experiences guide future behaviour. Sparse ensembles of neurons, known as engrams, are thought to store memories in the brain. Neurons involved in a particular engram (“engram neurons”) are necessary for subsequent memory express
Autor:
Albert Park, Alexander D. Jacob, Hwa-Lin Hsiang, Paul W. Frankland, John G. Howland, Sheena A. Josselyn
Publikováno v:
Neuropsychopharmacology. 48:724-733
Autor:
Alexander D. Jacob, Sheena A. Josselyn
Publikováno v:
Neuron
The prelimbic (PL) area and basolateral amygdala (lateral [LA] and basolateral [BL] nuclei) have closely related functions and similar extrinsic connectivity. Reasoning that the computational advantage of such redundancy should be reflected in differ
Throughout the brain, sparse ensembles of neurons, termed “engrams,” are responsible for representing events. Engrams are composed of neurons active at the time of an event, and recent research has revealed how these active neurons compete to gai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6befc35a43dd3f81fcca1b6a494b8094
https://doi.org/10.1093/oxfordhb/9780190069162.013.7
https://doi.org/10.1093/oxfordhb/9780190069162.013.7
Autor:
Paul W. Frankland, Daniel L. Schacter, Jocelyn M.H. Lau, Alexander D. Jacob, Sheena A. Josselyn, Asim J. Rashid
Publikováno v:
Neurobiol Learn Mem
Memory is a constructive, not reproductive, process that is prone to errors. Errors in memory, though, may originate from normally adaptive memory processes. At the extreme of memory distortion is falsely “remembering” an event that did not occur
Autor:
Rachel N. Newsome, Morgan D. Barense, Rosemary A. Cowell, Alexandra N. Trelle, Alexander D. Jacob, Celia Fidalgo, Bryan Hong, Jennifer D. Ryan, R. Shayna Rosenbaum, Victoria M. Smith
Publikováno v:
Learning & Memory. 25:31-44
The thalamic nuclei are thought to play a critical role in recognition memory. Specifically, the anterior thalamic nuclei and medial dorsal nuclei may serve as critical output structures in distinct hippocampal and perirhinal cortex systems, respecti
Autor:
Jung Hoon Jung, Asim J. Rashid, G. Andrew Woolley, Sheena A. Josselyn, Brandon J. Walters, Paul W. Frankland, Albert Park, Sungmo Park, Alexander D. Jacob, Jocelyn M.H. Lau
Publikováno v:
Neuropsychopharmacology
The internal representation of an experience is thought to be encoded by long-lasting physical changes to the brain (“engrams”) . Previously, we and others showed within the lateral amygdala (LA), a region critical for auditory conditioned fear,
Autor:
Lina M. Tran, Chen Yan, Alexander D. Jacob, Adam I. Ramsaran, Paul W. Frankland, Andrew J. Mocle, Sheena A. Josselyn
Miniaturized fluorescence microscopes for imaging calcium transients are a promising tool for investigating the relationship between behaviour and population-level neuronal activity in rodents. However, commercially available miniature microscopes ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dee343e2f89cdc400ccc81ca25903b2
https://doi.org/10.1101/252205
https://doi.org/10.1101/252205
Autor:
Paul W. Frankland, Adam I. Ramsaran, Sheena A. Josselyn, Andrew J. Mocle, Chen Yan, Lina M. Tran, Alexander D. Jacob
Publikováno v:
Current Protocols in Neuroscience. 84:e51
Miniaturized fluorescence microscopes for imaging calcium transients are a promising tool for investigating the relationship between behavior and population-level neuronal activity in rodents. However, commercially available miniature microscopes may