Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alexander D. Brown"'
Autor:
Sara Wong, Alexander D. Brown, Abigail B. Abrahams, An Nisaa Nurzak, Hoda M. Eltaher, David A. Sykes, Dmitry B. Veprintsev, Kevin C. F. Fone, James E. Dixon, Madeleine V. King
Publikováno v:
Pharmaceutics, Vol 16, Iss 10, p 1267 (2024)
Background/Objectives: Peptide-based treatments represent an expanding area and require innovative approaches to enhance bioavailability. Combination with cell-penetrating peptides (CPPs) is an attractive strategy to improve non-invasive delivery acr
Externí odkaz:
https://doaj.org/article/46e3a3fb62ff4c11b57c91f0106aeaf4
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 5, Pp 2562-2575 (2022)
Abstract Background Cell assays are important for investigating the mechanisms of ageing, including losses in protein homeostasis and ‘proteostasis collapse’. We used novel isotopic labelling and proteomic methods to investigate protein turnover
Externí odkaz:
https://doaj.org/article/d333dd1045a44f4b962f6970a9f7254f
Autor:
Alexander D. Brown, Joanne Sayner
Publikováno v:
Disrupted Knowledge ISBN: 9789004536418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a251eb54ab8f3ab0fc1d77a018a5efc9
https://doi.org/10.1163/9789004536418_009
https://doi.org/10.1163/9789004536418_009
Publikováno v:
California Fish and Wildlife Journal, Vol 107, Iss CESA Special Issue, Pp 416-437 (2021)
San Joaquin kit foxes (Vulpes macrotis mutica) are federally endangered and California threatened, primarily due to profound habitat loss. Kit foxes are obligate den users and in some locations den availability may be limited due to natural or anthro
Publikováno v:
Journal of cachexia, sarcopenia and muscle. 13(5)
Background: Cell assays are important for investigating the mechanisms of ageing, including losses in protein homeostasis and ‘proteostasis collapse’. We used novel isotopic labelling and proteomic methods to investigate protein turnover in repli
Autor:
Alexander D. Brown
This book presents ground-breaking research into the ‘Merker affair,'a series of events that took place in the German Democratic Republic (GDR) in the early 1950s, which saw Paul Merker, a member of the ruling party's ‘Politburo,'become ensnared
Autor:
Nir Eynon, Sarah Voisin, Claire E. Stewart, Daniil V. Popov, Piotr P. Gorski, R. Sultanov, I. Dos-Remedios, Philipp Baumert, Daniel J. Owens, Ildus I. Ahmetov, Adam P. Sharples, Ekaterina Semenova, Andrey K. Larin, Edward V. Generozov, Robert A. Seaborne, Robert M. Erskine, Oleg V. Borisov, Alexander D. Brown, Mark O. Kitchen, Mohd Firdaus Maasar, Daniel C. Turner, Barry Drust
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-19 (2020)
Scientific Reports
Scientific Reports
Skeletal muscle tissue demonstrates global hypermethylation with age. However, methylome changes across the time-course of differentiation in aged human muscle derived cells, and larger coverage arrays in aged muscle tissue have not been undertaken.
Publikováno v:
Proteomics. 21(1)
Mole (MSR) and fractional (FSR) synthesis rates of proteins during C2C12 myoblast differentiation were investigated. Myoblast cultures supplemented with D2O during 0–24 h or 72–96 h of differentiation were analysed by LC‐MS/MS to calculate prot
Publikováno v:
The Journal of Physiology. 598:3547-3548
Autor:
Daniel C, Turner, Andreas M, Kasper, Robert A, Seaborne, Alexander D, Brown, Graeme L, Close, Mark, Murphy, Claire E, Stewart, Neil R W, Martin, Adam P, Sharples
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1889
The bioengineering of skeletal muscle tissue in-vitro has enabled researchers to more closely mimic the in-vivo skeletal muscle niche. The three-dimensional (3-D) structure of the tissue engineered systems employed to date enable the generation of hi