Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Alexander D Rowe"'
Autor:
Stephan A Frye, Emma Lång, Getachew Tesfaye Beyene, Seetha V Balasingham, Håvard Homberset, Alexander D Rowe, Ole Herman Ambur, Tone Tønjum
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134954 (2015)
Expression of type IV pili (Tfp), filamentous appendages emanating from the bacterial surface, is indispensable for efficient neisserial transformation. Tfp pass through the secretin pore consisting of the membrane protein PilQ. PilG is a polytopic m
Externí odkaz:
https://doaj.org/article/92f43c8ecd1c4098829952528c28f5f2
Publikováno v:
PLoS Genetics, Vol 6, Iss 12, p e1001242 (2010)
Huntington's disease (HD) is one of several neurodegenerative disorders caused by expansion of CAG repeats in a coding gene. Somatic CAG expansion rates in HD vary between organs, and the greatest instability is observed in the brain, correlating wit
Externí odkaz:
https://doaj.org/article/3b73c7df450645bb8982c95a40b34612
Autor:
Gard O S Thomassen, Ragnhild Weel-Sneve, Alexander D Rowe, James A Booth, Jessica M Lindvall, Karin Lagesen, Knut I Kristiansen, Magnar Bjørås, Torbjørn Rognes
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15356 (2010)
BACKGROUND: Despite comprehensive investigation, the Escherichia coli SOS response system is not yet fully understood. We have applied custom designed whole genome tiling arrays to measure UV invoked transcriptional changes in E. coli. This study pro
Externí odkaz:
https://doaj.org/article/e4b5b4ce266345fabe02d0e87b921c6a
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5943 (2009)
BACKGROUND: High-density tiling microarrays are a powerful tool for the characterization of complete genomes. The two major computational challenges associated with custom-made arrays are design and analysis. Firstly, several genome dependent variabl
Externí odkaz:
https://doaj.org/article/6c648f1d8f504e4c95b5df05643bdd54
Autor:
Gunn A. Hildrestrand, Veslemøy Rolseth, Nicolas Kunath, Rajikala Suganthan, Vidar Jensen, Anna M. Bugaj, Marion S. Fernandez-Berrocal, Sunniva B. Sikko, Susanne Vetlesen, Anna Kuśnierczyk, Ann-Karin Olsen, Kristine B. Gützkow, Alexander D. Rowe, Wei Wang, Olve Moldestad, Monica D. Syrstad, Geir Slupphaug, Lars Eide, Arne Klungland, Pål Sætrom, Luisa Luna, Jing Ye, Katja Scheffler, Magnar Bjørås
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Gunn Hildrestrand, Veslemøy Rolseth, and Nicolas Kunath et al. examine mice lacking the NEIL1 and NEIL2 DNA glycosylases involved in base excision repair. Their results suggest that loss of both NEIL1 and NEIL2 dysregulates genes relevant to synapti
Externí odkaz:
https://doaj.org/article/36b704fa17dc44b1933173201d933187
Autor:
Arash Ahmadi, Katharina Till, Paul Hoff Backe, Pernille Blicher, Robin Diekmann, Mark Schüttpelz, Kyrre Glette, Jim Tørresen, Magnar Bjørås, Alexander D. Rowe, Bjørn Dalhus
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Ahmadi et al. use a single-molecule tracking method to describe the DNA scanning mode of AlkD, a HEAT-like repeat DNA glycosylase. They show that, contrary to other glycosylases that use a base-flipping mechanism, AlkD scans the DNA without forming a
Externí odkaz:
https://doaj.org/article/dc979ac48443432c9defb5314d98f0c6
Autor:
Arash Ahmadi, Ida Rosnes, Pernille Blicher, Robin Diekmann, Mark Schüttpelz, Kyrre Glette, Jim Tørresen, Magnar Bjørås, Bjørn Dalhus, Alexander D. Rowe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
How DNA repair proteins locate their target sites on DNA is still a matter of debate. Here the authors characterize by single-molecule fluorescence imaging the modes of scanning adopted by bacterial endonuclease V as it moves along linear DNA tracks.
Externí odkaz:
https://doaj.org/article/731b5efe4af24923bd07d7a709bb4c09
Autor:
Emma Lång, Anna Połeć, Anna Lång, Marijke Valk, Pernille Blicher, Alexander D. Rowe, Kim A. Tønseth, Catherine J. Jackson, Tor P. Utheim, Liesbeth M. C. Janssen, Jens Eriksson, Stig Ove Bøe
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Epithelial sheet migration requires polarized and coordinated cell movement. Here, the authors demonstrate serum-activated collective migration followed by polarized asymmetric cell divisions in otherwise quiescent human keratinocyte monolayers in th
Externí odkaz:
https://doaj.org/article/56730725888641c7b0f946697f96d47e
Autor:
Beibei Zhang, Pilar Ayuda-Durán, Laure Piechaczyk, Yngvar Fløisand, Mireia Mayoral Safont, Ida Tveit Karlsen, Zina Fandalyuk, Dagim Tadele, Pepijn van Mierlo, Alexander D. Rowe, Joseph M. Robertson, Bjørn Tore Gjertsen, Emmet McCormack, Jorrit M. Enserink
Publikováno v:
Haematologica, Vol 104, Iss 5 (2019)
Externí odkaz:
https://doaj.org/article/70072394fa2a4fc1babe00737e6d8cec
Autor:
Alexander D. Rowe, Stephanie D. Stoway, Henrik Åhlman, Vaneet Arora, Michele Caggana, Anna Fornari, Arthur Hagar, Patricia L. Hall, Gregg C. Marquardt, Bobby J. Miller, Christopher Nixon, Andrew P. Norgan, Joseph J. Orsini, Rolf D. Pettersen, Amy L. Piazza, Neil R. Schubauer, Amy C. Smith, Hao Tang, Norma P. Tavakoli, Sainan Wei, Rolf H. Zetterström, Robert J. Currier, Lars Mørkrid, Piero Rinaldo
Publikováno v:
International Journal of Neonatal Screening, Vol 7, Iss 2, p 23 (2021)
Newborn screening for congenital hypothyroidism remains challenging decades after broad implementation worldwide. Testing protocols are not uniform in terms of targets (TSH and/or T4) and protocols (parallel vs. sequential testing; one or two specime
Externí odkaz:
https://doaj.org/article/067a1ce7f8054700bd2a9e137d4cc7c0