Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alexander D, Jacobs"'
Autor:
Michael J. Maroney, Alexander D. Jacobs, Khadine A. Higgins, Yue Fu, Daiana A. Capdevila, rd H. Jerome Coyne, J. Martin, David P. Giedroc, Yifan Zhang, Kevin E. Bruce, David E. Clemmer, Hendrik Glauninger
Publikováno v:
Chemical Science. 9:105-118
Resistance to copper (Cu) toxicity in the respiratory pathogen Streptococcus pneumoniae is regulated by the Cu-specific metallosensor CopY. CopY is structurally related to the antibiotic-resistance regulatory proteins MecI and BlaI from Staphylococcu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0512fa23e336abe6bcd724417117581
https://doi.org/10.1039/c7sc04396a
https://doi.org/10.1039/c7sc04396a
Autor:
Alexander D. Jacobs, Chul-Hyun Kim, Edward Smith, C. Cheng Kao, David E. Clemmer, Haley Hoover
Publikováno v:
Nucleic Acids Research
In the brome mosaic virus (BMV) virion, the coat protein (CP) selectively contacts the RNA motifs that regulate translation and RNA replication (Hoover et al., 2016. J. Virol. 90, 7748). We hypothesize that the unstructured N-terminal arm (NTA) of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aaecd8a7c3aed66f2f0067b303e6686
https://doi.org/10.1093/nar/gkx1087
https://doi.org/10.1093/nar/gkx1087
Autor:
Vicki H. Wysocki, Feng-Ming James Chang, Lindsay J. Morrison, Alexander D. Jacobs, David E. Clemmer, David P. Giedroc, Jonathan M. Dilger
Publikováno v:
Angewandte Chemie International Edition. 54:12795-12799
The cooperativity of ligand binding is central to biological regulation and new approaches are needed to quantify these allosteric relationships. Herein, we exploit a suite of mass spectrometry (MS) experiments to provide novel insights into homotrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152e05d5aba923711bf770978e0d48ae
https://doi.org/10.1002/anie.201506349
https://doi.org/10.1002/anie.201506349
Autor:
David E. Clemmer, Krishnan Raghavachari, K. V. Jovan Jose, Alexander D. Jacobs, Megan C. Thielges, Rachel E. Horness
Ion mobility spectrometry-mass spectrometry and Fourier transform infrared spectroscopy (FTIR) techniques were combined with quantum chemical calculations to examine the origin of icosahedral clusters of the amino acid proline. When enantiopure proli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3148c3406ab6d39690503158f26977
https://europepmc.org/articles/PMC6884317/
https://europepmc.org/articles/PMC6884317/
Autor:
Hendrik, Glauninger, Yifan, Zhang, Khadine A, Higgins, Alexander D, Jacobs, Julia E, Martin, Yue, Fu, H Jerome, Coyne Rd, Kevin E, Bruce, Michael J, Maroney, David E, Clemmer, Daiana A, Capdevila, David P, Giedroc
Publikováno v:
Chemical Science
The dynamics and marginal stability of CopY enable allosteric activation of DNA binding by Zn(ii) and inhibition by Cu(i).
Resistance to copper (Cu) toxicity in the respiratory pathogen Streptococcus pneumoniae is regulated by the Cu-specific me
Resistance to copper (Cu) toxicity in the respiratory pathogen Streptococcus pneumoniae is regulated by the Cu-specific me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1c18187430669ce984c48cd5c07c6b6
https://pubmed.ncbi.nlm.nih.gov/29399317
https://pubmed.ncbi.nlm.nih.gov/29399317
Autor:
Paul E. Anderson, Jihad S. Obeid, Jim C. Oates, Cassios K. Marques, Diane L. Kamen, Clayton A. Turner, Alexander D. Jacobs
Publikováno v:
BMC Medical Informatics and Decision Making
Background Identifying patients with certain clinical criteria based on manual chart review of doctors’ notes is a daunting task given the massive amounts of text notes in the electronic health records (EHR). This task can be automated using text c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371f1bdff8c87efb5709bb3485c4ef10
http://europepmc.org/articles/PMC5568290
http://europepmc.org/articles/PMC5568290
Autor:
Markus Tuller, Roberto Furfaro, Wolfgang Fink, Ramaprasad Kulkarni, Victor R. Baker, Mark A. Tarbell, Alexander D. Jacobs
Publikováno v:
2012 IEEE Aerospace Conference.
We introduce a robotic lake lander test bed that can be operated either stand-alone or as part of a Tier-Scalable Reconnaissance mission architecture to study and field test an integrated hardware and software framework for fully autonomous surface a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bb169fc152bf53803843b100f94a628
https://doi.org/10.1109/aero.2012.6187056
https://doi.org/10.1109/aero.2012.6187056
Autor:
Joshua A. Danish, David Phelps, Diane Glosson, Kylie Peppler, Benjamin Zaitlen, Alexander D. Jacobs
Publikováno v:
IDC
New technologies have enabled students to become active participants in computational simulations of dynamic and complex systems (called Participatory Simulations), providing a "first-person" perspective on complex systems. However, most existing Par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98f4d8ce0a3177809af2f4e891f3e989
https://doi.org/10.1145/1810543.1810582
https://doi.org/10.1145/1810543.1810582