Astrocyte Intracellular Ca2+and TrkB Signaling in the Hippocampus Could Be Involved in the Beneficial Behavioral Effects of Antidepressant Treatment

Autor: Frederico Rogério Ferreira, Wilson A. Silva, Alexander Cupido, Francisco Silveira Guimarães, Elaine Del-Bel, Bogdan Catalin, Frank Kirchhoff

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Although monoaminergic-based antidepressant drugs are largely used to treat major depressive disorder (MDD), their mechanisms are still incompletely understood. Intracellular Ca2+ (iCa2+) and Calmodulin 1(CaM-1) homeostasis have been proposed to part

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e83cdbf658869abedc523f4ae10be1
https://doi.org/10.1007/s12640-021-00334-0

The effect of an mGluR5 inhibitor on procedural memory and avoidance discrimination impairments in Fmr1 KO mice

Autor: Sebastiaan K. E. Koekkoek, C. I. De Zeeuw, Ben A. Oostra, Jan-Willem Potters, M. F. Vinueza Veloz, Alexander Cupido, Laurens W. J. Bosman, Ronald A.M. Buijsen, Rob Willemsen

Publikováno v: Genes Brain and Behavior, 11(3), 325-331. Wiley-Blackwell Publishing Ltd
Genes, Brain, and Behavior
Genes Brain and Behavior, 11, 325-331. Wiley-Blackwell

Fragile X syndrome (FXS) is the most common inherited form of intellectual disability. Patients with FXS do not only suffer from cognitive problems, but also from abnormalities/deficits in procedural memory formation. It has been proposed that a lack

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c556b38b9076c89fb1fa8e9bd473a4
https://doi.org/10.1111/j.1601-183x.2011.00763.x

Bergmann glial AMPA receptors are required for fine motor coordination

Autor: Alexander Cupido, Rolf Sprengel, Hannah Monyer, Alexander Neumeyer, Chris I. De Zeeuw, Karim Le Meur, Magdalena Götz, Hannah M. Jahn, Aiman S. Saab, Joachim W. Deitmer, Antonia A. M. Šimek, Frank Kirchhoff, Maria E. Rubio, Anja Scheller, Henk-Jan Boele

Publikováno v: Science; Vol 337
Science, 337(6095), 749-753. American Association for the Advancement of Science
Science Magazine, 337, 749-753. American Association for the Advancement of Science (AAAS)
Science

Crucial Cerebellar Glial Cells The role of glial cells and their interaction with neurons in normal behavior is unclear. To address this question, Saab et al. (p. 749 , published online 5 July) studied a special type of glial cell in the cerebellum.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7d931562bf01e8aa3571340dbfcfbb
https://pubmed.ncbi.nlm.nih.gov/22767895