Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Alexander Cao"'
Autor:
Razvan Cristescu, Andrey Loboda, Robert Orlowski, Vicky Makker, Matthew H Taylor, Carol Aghajanian, Petar Jelinic, Lea Dutta, Allen L Cohn, Marcia S Brose, Christopher Di Simone, Zhu Alexander Cao, Leah Suttner, Junji Matsui, Corina E Dutcus, Yukinori Minoshima, Mark J Messing
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background Lenvatinib plus pembrolizumab demonstrated clinically meaningful benefit in patients with previously treated advanced endometrial carcinoma in Study 111/KEYNOTE-146 (NCT02501096). In these exploratory analyses from this study, we evaluated
Externí odkaz:
https://doaj.org/article/1aba98f370d441fabd9fdd926cef1538
Autor:
Kohei Shitara, Kei Muro, Razvan Cristescu, Michael Nebozhyn, Andrey Loboda, Hyun Cheol Chung, Wasat Mansoor, Mustafa Ozguroglu, Mario Mandala, Maria Di Bartolomeo, Christian Caglevic, Julie Kobie, Min-Hee Ryu, Z Alexander Cao, Tomasz Olesinski, Eray Goekkurt, Raymond S McDermott, Zev A Wainberg, Chie-Schin Shih
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background In the randomized, controlled, phase III KEYNOTE-061 trial, second-line pembrolizumab did not significantly prolong overall survival (OS) versus paclitaxel in patients with PD-L1-positive (combined positive score ≥1) advanced gastric/gas
Externí odkaz:
https://doaj.org/article/47cdd46fe09d4f619548677a08c6eb63
Autor:
Ranee Mehra, Ina Rhee, Naiyer Rizvi, Robert L Ferris, Hussein Tawbi, Matthew D Hellmann, Sarah B Goldberg, Ryan J Sullivan, Helen X Chen, Jong Chul Park, Foluso O Ademuyiwa, Z Alexander Cao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Although immunotherapy can offer profound clinical benefit for patients with a variety of difficult-to-treat cancers, many tumors either do not respond to upfront treatment with immune checkpoint inhibitors (ICIs) or progressive/recurrent disease occ
Externí odkaz:
https://doaj.org/article/fd73b0fbb8884f60901ba9db5264d2cd
Autor:
Takashi Kojima, Sung-Bae Kim, Ken Kato, Antoine Hollebecque, Per Pfeiffer, Florian Lordick, Masahiro Tajika, Mark Ayers, Jared Lunceford, Manish Shah, Daniel Hochhauser, Peter Enzinger, Judith Raimbourg, Heung Tae Kim, A Craig Lockhart, Hendrick-Tobias Arkenau, Farid El-Hajbi, Pooja Bhagia, Z Alexander Cao, Shailaja Suryawanshi, Matt Marton
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/df03b38851d04671bfca314d3e6727c1
Autor:
Manish A Shah, Takashi Kojima, Daniel Hochhauser, Peter Enzinger, Judith Raimbourg, Antoine Hollebecque, Florian Lordick, Sung-Bae Kim, Masahiro Tajika, Albert Craig Lockhart, Hendrick-Tobias Arkenau, Farid El-Hajbi, Mukul Gupta, Per Pfeiffer, Pooja Bhagia, Zhu Alexander Cao, Jared Lunceford, Shailaja Suryawanshi, Mark Ayers, Matthew J Marton, Ken Kato
Publikováno v:
Future Oncology. 18:2783-2790
Aim: Investigate the relationship between response to pembrolizumab and expression of the 18-gene T cell-inflamed gene expression profile (TcellinfGEP) or PD-L1 combined positive score (CPS) in esophageal cancer. Materials & methods: This analysis in
Autor:
Nicole M. Myer, Kohei Shitara, Hyun C. Chung, Florian Lordick, Ronan J. Kelly, Zsolt Szabo, Z. Alexander Cao, Stephen Leong, David H. Ilson, Wilko Weichert
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 148:2023-2043
Autor:
Lucjan Wyrwicz, Kohei Shitara, Josep Tabernero, Sukrut Shah, Pooja Bhagia, Razvan Cristescu, Julie Kobie, Deepti Aurora-Garg, Z. Alexander Cao, Zev A. Wainberg, Joseph Chao, Hugo R. Castro, Jeeyun Lee, Hyun Cheol Chung, Marcelo Garrido, Iveta Kudaba, Charles S. Fuchs, Yung-Jue Bang, Eric Van Cutsem, Keun-Wook Lee
Purpose:This prespecified exploratory analysis evaluated the association between tumor mutational burden (TMB) status and outcomes of first-line pembrolizumab±chemotherapy versus chemotherapy in KEYNOTE-062.Patients and Methods:In patients with adva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01403f463b90e5ca063bb8cdee88edc8
https://doi.org/10.1158/1078-0432.c.6532410.v1
https://doi.org/10.1158/1078-0432.c.6532410.v1
Autor:
Andrey Loboda, Jared Lunceford, Mark Ayers, Alexandra Snyder, Terrill K. McClanahan, David W. Cescon, Petros Grivas, Antoni Ribas, Michael Morrissey, Z. Alexander Cao, Hua Ma, Anran Wang, Qing Zhao, Lingkang Huang, Julie Kobie, Andrew Albright, Chunsheng Zhang, Michael Nebozhyn, Razvan Cristescu
Supplementary Figure from Transcriptomic Determinants of Response to Pembrolizumab Monotherapy across Solid Tumor Types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1059a802b7d1f57e86f1a41f898438ff
https://doi.org/10.1158/1078-0432.22486263.v1
https://doi.org/10.1158/1078-0432.22486263.v1
Autor:
Lucjan Wyrwicz, Kohei Shitara, Josep Tabernero, Sukrut Shah, Pooja Bhagia, Razvan Cristescu, Julie Kobie, Deepti Aurora-Garg, Z. Alexander Cao, Zev A. Wainberg, Joseph Chao, Hugo R. Castro, Jeeyun Lee, Hyun Cheol Chung, Marcelo Garrido, Iveta Kudaba, Charles S. Fuchs, Yung-Jue Bang, Eric Van Cutsem, Keun-Wook Lee
Supplementary Figure from Association of Tumor Mutational Burden with Efficacy of Pembrolizumab±Chemotherapy as First-Line Therapy for Gastric Cancer in the Phase III KEYNOTE-062 Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e60a640cfc1ef310c83ecc858b5d4b
https://doi.org/10.1158/1078-0432.22486896.v1
https://doi.org/10.1158/1078-0432.22486896.v1
Autor:
David C. Blakey, Vahe Bedian, Patricia McCoon, Lourdes Pablo, Brenda McDermott, Steve Emery, Mohammad Tabrizi, Joe Q. Zhou, Shenghua Wen, Corinne Reimer, Jane Kendrew, Maria Pinzon-Ortiz, Z. Alexander Cao, Jeffrey L. Brown
Localized angiopoietin-2 (Ang2) expression has been shown to function as a key regulator of blood vessel remodeling and tumor angiogenesis, making it an attractive candidate for antiangiogenic therapy. A fully human monoclonal antibody (3.19.3) was d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417b159458fb57091d42230f783d8590
https://doi.org/10.1158/1535-7163.c.6531830.v1
https://doi.org/10.1158/1535-7163.c.6531830.v1