Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Alexander C. Thompson"'
Autor:
Rachael Theresa Richardson, Michael R. Ibbotson, Alexander C. Thompson, Andrew K. Wise, James B. Fallon
Publikováno v:
Healthcare Technology Letters (2020)
Electrical stimulation has been used for decades in devices such as pacemakers, cochlear implants and more recently for deep brain and retinal stimulation and electroceutical treatment of disease. However, current spread from the electrodes limits th
Externí odkaz:
https://doaj.org/article/8aa481fd20454544a3dc449b10ced27c
Auditory nerve responses to combined optogenetic and electrical stimulation in chronically deaf mice
Autor:
Elise A Ajay, Ella P Trang, Alexander C Thompson, Andrew K Wise, David B Grayden, James B Fallon, Rachael T Richardson
Publikováno v:
Journal of Neural Engineering. 20:026035
Objective. Optogenetic stimulation of the auditory nerve offers the ability to overcome the limitations of cochlear implants through spatially precise stimulation, but cannot achieve the temporal precision nor temporal fidelity required for good hear
Autor:
Alexander C. Thompson, Katarzyna Matczyszyn, Ifor D. W. Samuel, Ewelina Wanarska, Irena Maliszewska
Publikováno v:
Molecules, Vol 26, Iss 623, p 623 (2021)
Molecules
Volume 26
Issue 3
Molecules
Volume 26
Issue 3
Antibiotic resistance is a growing concern that is driving the exploration of alternative ways of killing bacteria. Here we show that gold nanoparticles synthesized by the mycelium of Mucor plumbeus are an effective medium for antimicrobial photodyna
Autor:
Elise A Ajay, Alexander C. Thompson, Stephen O'Leary, Paul R. Stoddart, Niliksha Gunewardene, James B Fallon, Rachael T. Richardson, Andrew K. Wise
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Optical stimulation is a paradigm-shifting approach to modulating neural activity that has the potential to overcome the issue of current spread that occurs with electrical stimulation by providing focused stimuli. But optical stimulation either requ
Chronic intracochlear electrical stimulation at high charge densities: reducing platinum dissolution
Autor:
Brianna O. Flynn, Paul Carter, Ella P Trang, Robert K. Shepherd, James B Fallon, Alexander C. Thompson, Ashley N Dalrymple, Ya Lang Enke
Publikováno v:
J Neural Eng
OBJECTIVE: Histological examination of cochleae from long-term cochlear implant users has shown evidence of particulate platinum (Pt) corroded from the surface of Pt electrodes. The pathophysiological effect of Pt within the cochlea has not been exte
Autor:
Michael R. Ibbotson, James B Fallon, Rachael T. Richardson, Alexander C. Thompson, Andrew K. Wise
Publikováno v:
Healthcare Technology Letters
Healthcare Technology Letters (2020)
Healthcare Technology Letters (2020)
Electrical stimulation has been used for decades in devices such as pacemakers, cochlear implants and more recently for deep brain and retinal stimulation and electroceutical treatment of disease. However, current spread from the electrodes limits th
Publikováno v:
Expert Opinion on Biological Therapy. 17:213-223
Electrical stimulation has long been the most effective strategy for evoking neural activity from bionic devices and has been used with great success in the cochlear implant to allow deaf people to hear speech and sound. Despite its success, the spre
Autor:
William G. A. Brown, Tatiana Kameneva, Bryony A Nayagam, Paul R. Stoddart, Karina Needham, James Michael Begeng, Alexander C. Thompson
Publikováno v:
Journal of Neural Engineering. 18:046003
Objective. Infrared light can be used to modulate the activity of neuronal cells through thermally-evoked capacitive currents and thermosensitive ion channel modulation. The infrared power threshold for action potentials has previously been found to
Autor:
Alexander C. Thompson, Andrew K. Wise, Ya Lang Enke, Trung V. Nguyen, Paul Carter, James Firth, Ashley N Dalrymple, James B Fallon, Robert K. Shepherd
Publikováno v:
J Neural Eng
Objective. Established guidelines for safe levels of electrical stimulation for neural prostheses are based on a limited range of the stimulus parameters used clinically. Recent studies have reported particulate platinum (Pt) associated with long-ter
Autor:
Alexander C. Thompson, Paul R. Stoddart, James B Fallon, Tatiana Kameneva, Karina Needham, William L. Hart, Rachael T. Richardson, Andrew K. Wise
Publikováno v:
Journal of Neural Engineering. 17:016069
Objective The performance of neuroprostheses, including cochlear and retinal implants, is currently constrained by the spatial resolution of electrical stimulation. Optogenetics has improved the spatial control of neurons in vivo but lacks the fast-t