Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Alexander Brack"'
Autor:
Michael A. Harnik, Annemarie Sodmann, Beate Hartmannsberger, Gudrun Kindl, Juliane Becker, Ann-Kristin Reinhold, Eva Herrmann, Andreas K. Buck, Ulrich Dischinger, Frank Birklein, Alexander Brack, Abdelrahman Sawalma, Heike L. Rittner
Publikováno v:
PAIN Reports, Vol 9, Iss 6, p e1217 (2024)
Abstract. Introduction:. Patients with complex regional pain syndrome (CRPS) often show disturbed bone metabolism, assessed using three-phase bone scintigraphy (TPBS). However, current methods lack automation and standardisation. Bone serum markers h
Externí odkaz:
https://doaj.org/article/030b3c0267224a04a3d20f12edae625d
Autor:
Jeremy Tsung-Chieh Chen, Xiawei Hu, Isabel U.C. Otto, Christina Schürger, Bruno Rogalla von Bieberstein, Kathrin Doppler, Susanne M. Krug, Mohammed K. Hankir, Rosel Blasig, Claudia Sommer, Alexander Brack, Ingolf E. Blasig, Heike L. Rittner
Publikováno v:
Neurobiology of Disease, Vol 185, Iss , Pp 106246- (2023)
Background: The blood-nerve and myelin barrier shield peripheral neurons and their axons. These barriers are sealed by tight junction proteins, which control the passage of potentially noxious molecules including proinflammatory cytokines via paracel
Externí odkaz:
https://doaj.org/article/555600b0ece440f998ec1507add56ceb
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
Within the lipidome oxidized phospholipids (OxPL) form a class of chemically highly reactive metabolites. OxPL are acutely produced in inflamed tissue and act as endogenous, proalgesic (pain-inducing) metabolites. They excite sensory, nociceptive neu
Externí odkaz:
https://doaj.org/article/43989904f96b4c9dab06edffb79ae682
Autor:
Johannes Herrmann, Elisabeth Hannah Adam, Quirin Notz, Philipp Helmer, Michael Sonntagbauer, Peter Ungemach-Papenberg, Andreas Sanns, York Zausig, Thorsten Steinfeldt, Iuliu Torje, Benedikt Schmid, Tobias Schlesinger, Caroline Rolfes, Christian Reyher, Markus Kredel, Jan Stumpner, Alexander Brack, Thomas Wurmb, Daniel Gill-Schuster, Peter Kranke, Dirk Weismann, Hartwig Klinker, Peter Heuschmann, Viktoria Rücker, Stefan Frantz, Georg Ertl, Ralf Michael Muellenbach, Haitham Mutlak, Patrick Meybohm, Kai Zacharowski, Christopher Lotz
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Background: Proportions of patients dying from the coronavirus disease-19 (COVID-19) vary between different countries. We report the characteristics; clinical course and outcome of patients requiring intensive care due to COVID-19 induced acute respi
Externí odkaz:
https://doaj.org/article/702ec5c7b4314286a02928e35a2a5b4a
Autor:
Beatrice Oehler, Katrin Kistner, Corinna Martin, Jürgen Schiller, Rafaela Mayer, Milad Mohammadi, Reine-Solange Sauer, Milos R. Filipovic, Francisco R. Nieto, Jan Kloka, Diana Pflücke, Kerstin Hill, Michael Schaefer, Marzia Malcangio, Peter W. Reeh, Alexander Brack, Robert Blum, Heike L. Rittner
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-22 (2017)
Abstract Phospholipids occurring in cell membranes and lipoproteins are converted into oxidized phospholipids (OxPL) by oxidative stress promoting atherosclerotic plaque formation. Here, OxPL were characterized as novel targets in acute and chronic i
Externí odkaz:
https://doaj.org/article/a6c20966bd864799baf52d5a980c648e
Autor:
Beatrice Oehler, Milad Mohammadi, Cristina Perpina Viciano, Dagmar Hackel, Carsten Hoffmann, Alexander Brack, Heike L. Rittner
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Antinociceptive pathways are activated in the periphery in inflammatory pain, for instance resolvins and opioid peptides. Resolvins are biosynthesized from omega-3 polyunsaturated fatty acids such as eicosapentaenoic acid and docosahexaenoic acid. Re
Externí odkaz:
https://doaj.org/article/ca92544efbd8408ba8bd7a53fac11bd1
Autor:
Ying Wang, Rebekka Gehringer, Shaaban A Mousa, Dagmar Hackel, Alexander Brack, Heike L Rittner
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94696 (2014)
Acupuncture is widely used for pain treatment in patients with osteoarthritis or low back pain, but molecular mechanisms remain largely enigmatic. In the early phase of inflammation neutrophilic chemokines direct opioid-containing neutrophils in the
Externí odkaz:
https://doaj.org/article/bc6e7005a4454c6b86994d1748d4cda7
Autor:
Dagmar Hackel, Diana Pflücke, Annick Neumann, Johannes Viebahn, Shaaban Mousa, Erhard Wischmeyer, Norbert Roewer, Alexander Brack, Heike Lydia Rittner
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63564 (2013)
The interplay of specific leukocyte subpopulations, resident cells and proalgesic mediators results in pain in inflammation. Proalgesic mediators like reactive oxygen species (ROS) and downstream products elicit pain by stimulation of transient recep
Externí odkaz:
https://doaj.org/article/bd017c9ca6654bb8acd4b5c9499069fe
Autor:
Heike L Rittner, Dagmar Hackel, Philipp Voigt, Shaaban Mousa, Andrea Stolz, Dominika Labuz, Michael Schäfer, Michael Schaefer, Christoph Stein, Alexander Brack
Publikováno v:
PLoS Pathogens, Vol 5, Iss 4, p e1000362 (2009)
In inflammation, pain is regulated by a balance of pro- and analgesic mediators. Analgesic mediators include opioid peptides which are secreted by neutrophils at the site of inflammation, leading to activation of opioid receptors on peripheral sensor
Externí odkaz:
https://doaj.org/article/8bd0b088de6e41c88eec054879ea630d
Autor:
Ann Kristin, Reinhold, Gudrun-Karin, Kindl, Christopher, Dietz, Nathalie, Scheu, Katharina, Mehling, Alexander, Brack, Frank, Birklein, Heike L, Rittner
Publikováno v:
European Journal of Pain. 27:278-288
Complex regional pain syndrome (CRPS) is marked by disproportionate pain after trauma. While long-term outcome is crucial to patients, predictors or biomarkers of the course of pain or CRPS symptoms are still lacking. In particular, microRNAs, such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21049976643e0ce95e569240595ee89
https://doi.org/10.1002/ejp.2058
https://doi.org/10.1002/ejp.2058