Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Alexander Biedermann"'
Autor:
Alexander Biedermann, Maria Patra-Kneuer, Dimitrios Mougiakakos, Maike Büttner-Herold, Doris Mangelberger-Eberl, Johannes Berges, Christian Kellner, Sarah Altmeyer, Jörg Thomas Bittenbring, Christian Augsberger, Kristina Ilieva-Babinsky, Stefan Haskamp, Fabian Beier, Christopher Lischer, Julio Vera, Anja Lührmann, Simone Bertz, Simon Völkl, Benedikt Jacobs, Stefan Steidl, Andreas Mackensen, Heiko Bruns
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Macrophages are one of the key mediators of the therapeutic effects exerted by monoclonal antibodies, such as the anti-CD19 antibody tafasitamab, approved in combination with lenalidomide for the treatment of relapsed or refractory (r/r) diffuse larg
Externí odkaz:
https://doaj.org/article/83e0d53a47ba41ce83058f40a666be1f
Autor:
Thomas Heerde, Matthies Rennegarbe, Alexander Biedermann, Dilan Savran, Peter B. Pfeiffer, Manuel Hitzenberger, Julian Baur, Ioana Puscalau-Girtu, Martin Zacharias, Nadine Schwierz, Christian Haupt, Matthias Schmidt, Marcus Fändrich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Here, the authors present the cryo-EM structure of in vitro amyloid fibrils from recombinant SAA1.1 protein that were formed by seeding with fibrils purified from systemic AA amyloidosis tissue. This in vitro fibril structure resembles the structure
Externí odkaz:
https://doaj.org/article/1dc8229b0dcb4b2fa12efbe783d6a181
Autor:
Akanksha Bansal, Matthias Schmidt, Matthies Rennegarbe, Christian Haupt, Falk Liberta, Sabrina Stecher, Ioana Puscalau-Girtu, Alexander Biedermann, Marcus Fändrich
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Systemic AA amyloidosis is a protein misfolding disease caused by the formation of amyloid fibrils from serum amyloid A (SAA) protein. Here, the authors present the cryo-EM structures of AA amyloid fibrils isolated from mouse tissue and in vitro form
Externí odkaz:
https://doaj.org/article/15b5d0653a7f4fee9b6e4b37a7961e1e
Autor:
Julian Mustroph, Marzena Drzymalski, Maria Baier, Steffen Pabel, Alexander Biedermann, Bernadette Memmel, Melanie Durczok, Stefan Neef, Can Martin Sag, Bernhard Floerchinger, Leopold Rupprecht, Christof Schmid, York Zausig, Guillaume Bégis, Veronique Briand, Marie‐Laure Ozoux, Dorothee Tamarelle, Veronique Ballet, Philip Janiak, Philippe Beauverger, Lars S. Maier, Stefan Wagner
Publikováno v:
ESC Heart Failure, Vol 7, Iss 5, Pp 2871-2883 (2020)
Abstract Aims Excessive activation of Ca/calmodulin‐dependent kinase II (CaMKII) is of critical importance in heart failure (HF) and atrial fibrillation. Unfortunately, lack of selectivity, specificity, and bioavailability have slowed down developm
Externí odkaz:
https://doaj.org/article/57dc9a1530ee492497a97ff40956bd3e
Autor:
Philipp Hegner, Marzena Drzymalski, Alexander Biedermann, Bernadette Memmel, Melanie Durczok, Michael Wester, Bernhard Floerchinger, Zdenek Provaznik, Christof Schmid, York Zausig, Lars S. Maier, Stefan Wagner
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1932 (2022)
Background: In reverse-mode, cardiac sodium-calcium exchanger (NCX) can increase the cytoplasmic Ca2+ concentration in response to high intracellular Na+ levels, which may contribute to diastolic contractile dysfunction. Furthermore, increased sponta
Externí odkaz:
https://doaj.org/article/e8e11a5666a64d56aa6f189c8b32711f
Autor:
Michael Arzt, Marzena A. Drzymalski, Sarah Ripfel, Sebastian Meindl, Alexander Biedermann, Melanie Durczok, Karoline Keller, Julian Mustroph, Sylvia Katz, Maria Tafelmeier, Simon Lebek, Bernhard Flörchinger, Daniele Camboni, Sigrid Wittmann, Johannes Backs, Christof Schmid, Lars S. Maier, Stefan Wagner
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 331 (2022)
Background: Sleep-disordered breathing (SDB) is associated with increased oxidant generation. Oxidized Ca/calmodulin kinase II (CaMKII) can contribute to atrial arrhythmias by the stimulation of sarcoplasmic reticulum Ca release events, i.e., Ca spar
Externí odkaz:
https://doaj.org/article/a2095decfc87425bb101568db2da2249
Autor:
Naseer Iqbal, Ghulam Mustafa, Abdul Rehman, Alexander Biedermann, Bita Najafi, Peter A. Lieberzeit, Franz L. Dickert
Publikováno v:
Sensors, Vol 10, Iss 7, Pp 6361-6376 (2010)
A piezoelectric 10 MHz multichannel quartz crystal microbalance (MQCM), coated with six molecularly imprinted polystyrene artificial recognition membranes have been developed for selective quantification of terpenes emanated from fresh and dried Lami
Externí odkaz:
https://doaj.org/article/32055b0c91a84142ab8c2ed7178b6df6
Autor:
Alexander Biedermann, Doris Mangelberger-Eberl, Dimitrios Mougiakakos, Maike Büttner-Herold, Cindy Flamann, Christian Kellner, Sarah Altmeyer, Jörg Bittenbring, Christian Augsberger, Maria Patra-Kneuer, Karin Landgraf, Kristina Ilieva-Babinsky, Stefan Haskamp, Fabian Beier, Simon Voelkl, Christian Pallasch, Benedikt Jacobs, Stefan Steidl, Christina Heitmüller, Andreas Mackensen, Heiko Bruns
Publikováno v:
Blood. 140:9292-9293
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f26978fd3ba502ea889d2a05108a894
https://doi.org/10.1182/blood-2022-159955
https://doi.org/10.1182/blood-2022-159955
Autor:
Philippe Beauverger, Dorothee Tamarelle, Leopold Rupprecht, York Zausig, Véronique Briand, Philip Janiak, Christof Schmid, Marzena Drzymalski, Steffen Pabel, Stefan Neef, Maria J. Baier, Melanie Durczok, Can Martin Sag, Bernadette Memmel, Julian Mustroph, Veronique Ballet, Marie-Laure Ozoux, Alexander Biedermann, Bernhard Floerchinger, Lars S. Maier, Guillaume Begis, Stefan Wagner
Publikováno v:
ESC Heart Failure, Vol 7, Iss 5, Pp 2871-2883 (2020)
Aims Excessive activation of Ca/calmodulin-dependent kinase II (CaMKII) is of critical importance in heart failure (HF) and atrial fibrillation. Unfortunately, lack of selectivity, specificity, and bioavailability have slowed down development of inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a172c6847bf5eee443ff0b573f052d
https://doaj.org/article/57dc9a1530ee492497a97ff40956bd3e
https://doaj.org/article/57dc9a1530ee492497a97ff40956bd3e
