Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alexander Bernt"'
Autor:
Doaa Tawfik, Angela Zaccagnino, Alexander Bernt, Monika Szczepanowski, Wolfram Klapper, Albrecht Schwab, Holger Kalthoff, Anna Trauzold
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-17 (2020)
Abstract Background The human pancreatic cancer cell line A818–6 can be grown in vitro either as a highly malignant, undifferentiated monolayer (ML) or as three-dimensional (3D) single layer hollow spheres (HS) simulating a benign, highly different
Externí odkaz:
https://doaj.org/article/9b656db7e86545e5ae1471a8147f4dac
Autor:
Matthias Eden, Benjamin Meder, Mirko Völkers, Montatip Poomvanicha, Katrin Domes, M. Branchereau, P. Marck, Rainer Will, Alexander Bernt, Ashraf Rangrez, Matthias Busch, German Mouse Clinic Consortium, Martin Hrabě de Angelis, Christophe Heymes, Wolfgang Rottbauer, Patrick Most, Franz Hofmann, Norbert Frey
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Heart failure is a major public health issue but due to our poor disease understanding the current therapies are symptomatic. Here the authors identify Myoscape as a novel cardiac protein regulating membrane localization of the L-type calcium channel
Externí odkaz:
https://doaj.org/article/be1c405ffde14645b9a55bd92869f64e
Autor:
Matthias Eden, Benjamin Meder, Mirko Völkers, Montatip Poomvanicha, Katrin Domes, M. Branchereau, P. Marck, Rainer Will, Alexander Bernt, Ashraf Rangrez, Matthias Busch, Martin Hrabě de Angelis, Christophe Heymes, Wolfgang Rottbauer, Patrick Most, Franz Hofmann, Norbert Frey
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications 7, Article number: 11317 (2016); Published: 28 April 2016; Updated: 26 May 2016 The original version of this Article contained an error in the doi number, which was incorrectly given as 15.13155/ncomms11317. This has now been co
Externí odkaz:
https://doaj.org/article/f333c31d537f42398220a2972c182092
Autor:
Jost Pott, Annika Kluge, Astrid Rohrbeck, Ashraf Yusuf Rangrez, Norbert Frey, Alexander Bernt, Lucia Sophie Kilian, Robert Frauen, Derk Frank
Publikováno v:
Journal of Molecular and Cellular Cardiology. 129:130-143
Cardiac remodeling is induced by mechanical or humoral stress causing pathological changes to the heart. Here, we aimed at identifying the role of differentially regulated genes upon dynamic mechanical stretch. Microarray of dynamic stretch induced n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e2d38ea08512fca89176ae195d7fe0
https://doi.org/10.1016/j.yjmcc.2019.01.028
https://doi.org/10.1016/j.yjmcc.2019.01.028
Autor:
Anna Trauzold, Angela Zaccagnino, Monika Szczepanowski, Doaa Tawfik, Albrecht Schwab, Holger Kalthoff, Wolfram Klapper, Alexander Bernt
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-17 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-17 (2020)
Background The human pancreatic cancer cell line A818–6 can be grown in vitro either as a highly malignant, undifferentiated monolayer (ML) or as three-dimensional (3D) single layer hollow spheres (HS) simulating a benign, highly differentiated, du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7dbdf85c5770573f0d153474b7a6b7
http://europepmc.org/articles/PMC7106758
http://europepmc.org/articles/PMC7106758
Autor:
Norbert Frey, Andreas O. Helbig, Nesrin Schmiedel, Andreas Tholey, Derk Frank, Alexander Bernt, Anushka Deshpande, Samuel Sossalla, Andreas Jungmann, Ashraf Yusuf Rangrez, Ankush Borlepawar, Manju Kumari, Lynn Christen, Anca Remes, O J Mueller
Publikováno v:
Circulation Research. 125
Objective: In this study, using a Yeast two-hybrid screen, we identified the HECT domain-containing E3 ubiquitin ligase 3 (HECTD3) as one of the novel cardiac binding partners of SUMO2. Present study thus focusses on deciphering the cardiac function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0c0ade484d4d6690306ade3b53d7c82
https://doi.org/10.1161/res.125.suppl_1.800
https://doi.org/10.1161/res.125.suppl_1.800
Autor:
Eric Schulze-Bahr, Andreas Unger, Marcus Krüger, Sven Dittmann, Pankaj Yadav, Ashraf Yusuf Rangrez, Corinna Friedrich, Norbert Frey, Birgit Stallmeyer, Ankush Borlepawar, Wolfgang A. Linke, Stefan Peischard, Derk Frank, Philip Usinger, Hideo A. Baba, E. Schulze-Bahr, Guiscard Seebohm, Wolfram-Hubertus Zimmermann, Alexander Bernt
Publikováno v:
Circulation: Genomic and Precision Medicine. 12
Background: Familial atrial septal defect (ASD) has previously been attributed primarily to mutations in cardiac transcription factors. Here, we report a large, multi-generational family (78 members) with ASD combined with a late-onset dilated cardio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9b139aa2409560ee76c9430b08d4b3
https://doi.org/10.1161/circgen.119.002491
https://doi.org/10.1161/circgen.119.002491
Autor:
Derk Frank, Norbert Frey, Ashraf Yusuf Rangrez, Matthias Eden, Thalia S. Seeger, Katharina Stiebeling, Christian Kuhn, Alexander Bernt, Werner W. Franke, Christine Grund, Reza Poyanmehr
Publikováno v:
Journal of Molecular and Cellular Cardiology. 72:196-207
The intercalated disc (ID) is a major component of the cell-cell contact structures of cardiomyocytes and has been recognized as a hot spot for cardiomyopathy. We have previously identified Myozap as a novel cardiac-enriched ID protein, which interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb78df08aee62f1c740c3b2b485693b
https://doi.org/10.1016/j.yjmcc.2014.03.016
https://doi.org/10.1016/j.yjmcc.2014.03.016
Autor:
Guiscard Seebohm, E. Schulze-Bahr, Wolfram-Hubertus Zimmermann, Andreas Unger, Hideo Baba, Wolgang Linke, Philip Usinger, Pankaj Yadav, Marcus Krüger, Norbert Frey, Stefan Peischard, Eric Schulze-Bahr, Derk Frank, Alexander Bernt, Sven Dittmann, Corinna Friedrich, Ashraf Yusuf Rangrez, Birgit Stallmeyer, Ankush Borlepawar
Publikováno v:
Journal of the American College of Cardiology. 73:963
Atrial septal defect (ASD) is a common congenital heart defect. Its pathogenesis is not well defined, but mutations in cardiac transcription factor genes have been described in familial forms. Here, we report a large, multi-generational family with A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69f17724a48e27dd702287cba92f0c37
https://doi.org/10.1016/s0735-1097(19)31570-0
https://doi.org/10.1016/s0735-1097(19)31570-0
Autor:
Alexander Bernthz Jensen, Thorbjørn Erik Køppen Christensen, Clemens Weninger, Henrik Birkedal
Publikováno v:
Journal of Synchrotron Radiation, Vol 29, Iss 6, Pp 1420-1428 (2022)
As synchrotron facilities continue to generate increasingly brilliant X-rays and detector speeds increase, swift data reduction from the collected area detector images to more workable 1D diffractograms becomes of increasing importance. This work rep
Externí odkaz:
https://doaj.org/article/d6ddd35935444f93ac4d1b8f4dd77c70