Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Alexander Bello"'
Autor:
John Merluza, Johnny Ung, Kai Makowski, Alyssia Robinson, Kathy Manguiat, Nicole Mueller, Jonathan Audet, Julie Chih-Yu Chen, James E. Strong, Heidi Wood, Alexander Bello
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Neutralization assays are important for understanding and quantifying neutralizing antibody responses toward severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 lentivirus surrogate neutralization assay (SCLSNA) can
Externí odkaz:
https://doaj.org/article/8cd110eb4adb4ed6a093025d51035295
Autor:
Bryan D. Griffin, Mable Chan, Nikesh Tailor, Emelissa J. Mendoza, Anders Leung, Bryce M. Warner, Ana T. Duggan, Estella Moffat, Shihua He, Lauren Garnett, Kaylie N. Tran, Logan Banadyga, Alixandra Albietz, Kevin Tierney, Jonathan Audet, Alexander Bello, Robert Vendramelli, Amrit S. Boese, Lisa Fernando, L. Robbin Lindsay, Claire M. Jardine, Heidi Wood, Guillaume Poliquin, James E. Strong, Michael Drebot, David Safronetz, Carissa Embury-Hyatt, Darwyn Kobasa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Deer mice are natural hosts for a number of human pathogens. Here, Griffin et al. report that intranasal exposure of the North American deer mouse to SARS-CoV-2 results in virus replication and shedding, despite causing only mild or asymptomatic illn
Externí odkaz:
https://doaj.org/article/9da1c4d9e45e4f76a8779fa6d68d2b3b
Autor:
Hongzhao Li, Alexander Bello, Greg Smith, Dominic M S Kielich, James E Strong, Bradley S Pickering
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 3, p e0010285 (2022)
CRISPR (clustered regularly interspaced short palindromic repeats), an ancient defense mechanism used by prokaryotes to cleave nucleic acids from invading viruses and plasmids, is currently being harnessed by researchers worldwide to develop new poin
Externí odkaz:
https://doaj.org/article/25d4992587604365b80906f3358f5ac2
Autor:
Bryan D. Griffin, Bryce M. Warner, Mable Chan, Emelissa Valcourt, Nikesh Tailor, Logan Banadyga, Anders Leung, Shihua He, Amrit S. Boese, Jonathan Audet, Wenguang Cao, Estella Moffat, Lauren Garnett, Kevin Tierney, Kaylie N. Tran, Alixandra Albietz, Kathy Manguiat, Geoff Soule, Alexander Bello, Robert Vendramelli, Jessica Lin, Yvon Deschambault, Wenjun Zhu, Heidi Wood, Samira Mubareka, David Safronetz, James E. Strong, Carissa Embury-Hyatt, Darwyn Kobasa
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103530- (2021)
Summary: The golden hamster model of SARS-CoV-2 infection recapitulates key characteristics of COVID-19. In this work we examined the influence of the route of exposure, sex, and age on SARS-CoV-2 pathogenesis in hamsters. We report that delivery of
Externí odkaz:
https://doaj.org/article/1dddd0fc2f9b4f73a788f89eb812218d
Autor:
Guillaume Poliquin, Duane Funk, Shane Jones, Kaylie Tran, Charlene Ranadheera, Mable Hagan, Kevin Tierney, Allen Grolla, Amrinder Dhaliwal, Alexander Bello, Anders Leung, Cory Nakamura, Darwyn Kobasa, Darryl Falzarano, Lauren Garnett, Hugues Fausther Bovendo, Heinz Feldmann, Murray Kesselman, Gregory Hansen, Jason Gren, George Risi, Mia Biondi, Todd Mortimer, Trina Racine, Yvon Deschambault, Sam Aminian, Jocelyn Edmonds, Ray Sourette, Mark Allan, Lauren Rondeau, Sharron Hadder, Christy Press, Christine DeGraff, Stephanie Kucas, Bradley W. M. Cook, B. J. Hancock, Anand Kumar, Reeni Soni, Darryl Schantz, Jarrid McKitrick, Bryce Warner, Bryan D. Griffin, Xiangguo Qiu, Gary P. Kobinger, Dave Safronetz, Derek Stein, Todd Cutts, James Kenny, Geoff Soule, Robert Kozak, Steven Theriault, Liam Menec, Robert Vendramelli, Sean Higgins, Guodong Liu, Niaz Md Rahim, Samantha Kasloff, Angela Sloan, Shihua He, Nikesh Tailor, Michael Gray, James E. Strong
Publikováno v:
Intensive Care Medicine Experimental, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background There are currently limited data for the use of specific antiviral therapies for the treatment of Ebola virus disease (EVD). While there is anecdotal evidence that supportive care may be effective, there is a paucity of direct exp
Externí odkaz:
https://doaj.org/article/877aaa5f56994221966d8a8be6302d4a
Autor:
Bryan D. Griffin, Kar Muthumani, Bryce M. Warner, Anna Majer, Mable Hagan, Jonathan Audet, Derek R. Stein, Charlene Ranadheera, Trina Racine, Marc-Antoine De La Vega, Jocelyne Piret, Stephanie Kucas, Kaylie N. Tran, Kathy L. Frost, Christine De Graff, Geoff Soule, Leanne Scharikow, Jennifer Scott, Gordon McTavish, Valerie Smid, Young K. Park, Joel N. Maslow, Niranjan Y. Sardesai, J. Joseph Kim, Xiao-jian Yao, Alexander Bello, Robbin Lindsay, Guy Boivin, Stephanie A. Booth, Darwyn Kobasa, Carissa Embury-Hyatt, David Safronetz, David B. Weiner, Gary P. Kobinger
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Zika virus (ZIKV) can persist in human semen and sperm, which can result in sexual transmission. Here, Griffinet al. show that a DNA vaccine, expressing ZIKV pre-membrane and envelope proteins, protects mice from infection-associated damage to testes
Externí odkaz:
https://doaj.org/article/0c82ce7b193e4897a52f784c15fa050c
Autor:
P. Guillaume Poliquin, Mia Biondi, Charlene Ranadheera, Mable Hagan, Alexander Bello, Trina Racine, Mark Allan, Duane Funk, Gregory Hansen, BJ Hancock, Murray Kesselman, Todd Mortimer, Anand Kumar, Shane Jones, Anders Leung, Allen Grolla, Kaylie N. Tran, Kevin Tierney, Xiangguo Qiu, Darwyn Kobasa, James E. Strong
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Critical care needs have been rising in recent decades as populations age and comorbidities increase. Sepsis-related admissions to critical care contribute up to 50% of volume and septic shock carries a 35–54% fatality rate. Improvements i
Externí odkaz:
https://doaj.org/article/b07496af4298487aa6560c75edfdb595
Autor:
Guillaume Poliquin, Duane Funk, Shane Jones, Kaylie Tran, Charlene Ranadheera, Mable Hagan, Kevin Tierney, Allen Grolla, Amrinder Dhaliwal, Alexander Bello, Anders Leung, Cory Nakamura, Darwyn Kobasa, Darryl Falzarano, Lauren Garnett, Hugues Fausther Bovendo, Heinz Feldmann, Murray Kesselman, Gregory Hansen, Jason Gren, George Risi, Mia Biondi, Todd Mortimer, Trina Racine, Yvon Deschambault, Sam Aminian, Jocelyn Edmonds, Ray Saurette, Mark Allan, Lauren Rondeau, Sharron Hadder, Christy Press, Christine DeGraff, Stephanie Kucas, Bradley W. M. Cook, B. J. Hancock, Anand Kumar, Reeni Soni, Daryl Schantz, Jarrid McKitrick, Bryce Warner, Bryan D. Griffin, Xiangguo Qiu, Gary P. Kobinger, Dave Safronetz, Derek Stein, Todd Cutts, James Kenny, Geoff Soule, Robert Kozak, Steven Theriault, Liam Menec, Robert Vendramelli, Sean Higgins, Logan Banadyga, Guodong Liu, Md Niaz Rahim, Samantha Kasloff, Angela Sloan, Shihua He, Nikesh Tailor, Alixandra Albietz, Brad Pickering, Gary Wong, Michael Gray, James E. Strong
Publikováno v:
Intensive Care Medicine Experimental, Vol 7, Iss 1, Pp 1-2 (2019)
Please note that four authors (Logan Banadyga, Alixandra Albietz, Brad Pickering, and Gary Wong) have been erroneously omitted from the author list in the published original article [1].
Externí odkaz:
https://doaj.org/article/52f8a5052d594c9f80e0472e6f5934a9
Autor:
Mia J. Biondi, Lauren Garnett, Alexander Bello, Duane Funk, Philippe Guillaume Poliquin, Shane Jones, Kevin Tierney, Kaylie Tran, Robert A. Kozak, Anders Leung, Allen Grolla, Cory Nakamura, Geoff Soule, Charlene Ranadheera, Mable Hagan, Amrinder Dhaliwal, Darwyn Kobasa, Darryl Falzarano, Hugues Fausther Bovendo, Heinz Feldmann, Murray Kesselman, Gregory Hansen, Jason Gren, Todd Mortimer, Trina Racine, Yvon Deschambault, Jocelyn Edmonds, Sam Aminian, Ray Saurette, Mark Allan, Lauren Rondeau, John Huynh, Sharron Hadder, Christy Press, Christine DeGraff, Stephanie Kucas, Julie Kubay, Kim Azanarsky, Bradley W. M. Cook, BJ Hancock, Anand Kumar, Reeni Soni, Daryl Schantz, Jarrid McKitrick, Bryce Warner, Bryan D. Griffin, Xiangguo Qiu, Gary P. Kobinger, Dave Safronetz, Heidi Wood, Derek R. Stein, Todd Cutts, Brad Pickering, James Kenny, Steven Theriault, Liam Menec, Robert Vendramelli, Sean Higgins, Logan Banadyga, Guodong Liu, Md Niaz Rahim, Samantha Kasloff, Angela Sloan, Shihua He, Nikesh Tailor, Alixandra Albietz, Gary Wong, Michael Gray, Friederike Feldmann, Andrea Marzi, George Risi, James E. Strong
Publikováno v:
Microorganisms, Vol 9, Iss 3, p 498 (2021)
Background: The 2014–2016 Ebola outbreak in West Africa recapitulated that nosocomial spread of Ebola virus could occur and that health care workers were at particular risk including notable cases in Europe and North America. These instances highli
Externí odkaz:
https://doaj.org/article/eb04787f538d495ca4be11c75ad187ee
Autor:
Agostina Puppo, Alexander Bello, Anna Manfredi, Giulia Cesi, Elena Marrocco, Michele Della Corte, Settimio Rossi, Massimo Giunti, Maria Laura Bacci, Francesca Simonelli, Enrico Maria Surace, Gary P Kobinger, Alberto Auricchio
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59025 (2013)
Recombinant adeno-associated viral (AAV) vectors are known to safely and efficiently transduce the retina. Among the various AAV serotypes available, AAV2/5 and 2/8 are the most effective for gene transfer to photoreceptors (PR), which are the most r
Externí odkaz:
https://doaj.org/article/c27b4ba715774c49ae34956b65b4bf20