Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alexander B. Tong"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Ring ATPase translocases that operate on disordered substrates adopt lockwasher architectures and use a hand-over-hand mechanism. By challenging the dsDNA packaging motor of bacteriophage ϕ29 with hybrid and dsRNA, the authors propose that the motor
Externí odkaz:
https://doaj.org/article/fd2702eb7c8e4254a416e2dbc6cb6580
Autor:
Mingxuan Sun, Hossein Amiri, Alexander B. Tong, Keishi Shintomi, Tatsuya Hirano, Carlos Bustamante, Rebecca Heald
Publikováno v:
Proceedings of the National Academy of Sciences. 120
DNA compaction is required for the condensation and resolution of chromosomes during mitosis, but the relative contribution of individual chromatin factors to this process is poorly understood. We developed a physiological, cell-free system using hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3738c6352a24cf6ba0c7dccb3af07bd4
https://doi.org/10.1073/pnas.2221309120
https://doi.org/10.1073/pnas.2221309120
Autor:
Alexander B. Tong, Carlos Bustamante
Publikováno v:
Biophysical Reviews
Ring ATPases perform a variety of tasks in the cell. Their function involves complex communication and coordination among the often identical subunits. Translocases in this group are of particular interest as they involve both chemical and mechanical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4119123c3dec14383a25411f115416
https://doi.org/10.1007/s12551-021-00883-w
https://doi.org/10.1007/s12551-021-00883-w
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature communications, vol 12, iss 1
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications
Ring ATPases that translocate disordered polymers possess lock-washer architectures that they impose on their substrates during transport via a hand-over-hand mechanism. Here, we investigate the operation of ring motors that transport ordered, helica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ffe6c7fe80cde287b6c485c02f4201
https://doaj.org/article/fd2702eb7c8e4254a416e2dbc6cb6580
https://doaj.org/article/fd2702eb7c8e4254a416e2dbc6cb6580
Autor:
A. King Cada, Mark R. Pavlin, Juan P. Castillo, Alexander B. Tong, Kevin P. Larsen, Xuefeng Ren, Adam L. Yokom, Feng-Ching Tsai, Jamie V. Shiah, Patricia M. Bassereau, Carlos J. Bustamante, James H. Hurley
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The endosomal sorting complexes required for transport (ESCRT) system is an ancient and ubiquitous membrane scission machinery that catalyzes the budding and scission of membranes. ESCRT-mediated scission events, exemplified by those involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cda6de2588365e0ae96e72b9cd102a
https://doi.org/10.1073/pnas.2204536119
https://doi.org/10.1073/pnas.2204536119
Autor:
Pietro Fontana, Ying Dong, Xiong Pi, Alexander B. Tong, Corey W. Hecksel, Longfei Wang, Tian-Min Fu, Carlos Bustamante, Hao Wu
Publikováno v:
Science
INTRODUCTION The nuclear pore complex (NPC) is the molecular conduit in the nuclear membrane of eukaryotic cells that regulates import and export of biomolecules between the nucleus and the cytosol, with vertebrate NPCs ~110 to 125 MDa in molecular m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2453b7d9d5148d4b89233d426e40e26
https://doi.org/10.1126/science.abm9326
https://doi.org/10.1126/science.abm9326
Autor:
Liang Meng Wee, Alexander B. Tong, Alfredo Jose Florez Ariza, Cristhian Cañari-Chumpitaz, Patricia Grob, Eva Nogales, Carlos J. Bustamante
Publikováno v:
Cell, vol 186, iss 6
In prokaryotes, translation can occur on mRNA that is being transcribed in a process called coupling. How the ribosome affects the RNA polymerase (RNAP) during coupling is not well understood. Here, we reconstituted the E.coli coupling system and dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43172b49f65ad44cd3613e33789cd2d
https://doi.org/10.1016/j.cell.2023.02.008
https://doi.org/10.1016/j.cell.2023.02.008
Autor:
A. King Cada, Mark R. Pavlin, Juan P. Castillo, Alexander B. Tong, Kevin P. Larsen, Xuefeng Ren, Adam Yokom, Feng-Ching Tsai, Jamie Shiah, Patricia M. Bassereau, Carlos J. Bustamante, James H. Hurley
The endosomal sorting complexes required for transport (ESCRT) system is an ancient and ubiquitous membrane scission machinery that catalyzes the budding and scission of membranes. ESCRT-mediated scission events, exemplified by those involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c97f243a496e2e54cc46b38e2fe68c5c
https://doi.org/10.1101/2022.02.03.479062
https://doi.org/10.1101/2022.02.03.479062
Autor:
Alexander B, Tong, Jason D, Burch, Daniel, McKay, Carlos, Bustamante, Michael A, Crackower, Hao, Wu
Publikováno v:
Nature structuralmolecular biology. 28(10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98240291e5ecd6af2ee67628205aefc0
https://pubmed.ncbi.nlm.nih.gov/34561631
https://pubmed.ncbi.nlm.nih.gov/34561631
Autor:
Bobo Feng, Kai Jiang, Per Lincoln, Carlos Bustamante, Fredrik Westerlund, Alexander B. Tong, Robert P Sosa, Masayuki Takahashi, Anna K. F. Mårtensson, Kevin D. Dorfman, Bengt Nordén
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The main stabilizer of the DNA double helix is not the base-pair hydrogen bonds but coin-pile stacking of base pairs, whose hydrophobic cohesion, requiring abundant water, indirectly makes the DNA interior dry so that hydrogen bonds can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac7da082b3ee52f4d7480c449398442
http://europepmc.org/articles/PMC6717297
http://europepmc.org/articles/PMC6717297