Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alexander B. Ansaldo"'
Autor:
Lynlee L Lin, Tarl W Prow, Anthony P Raphael, Robert L Harrold III, Clare A Primiero, Alexander B Ansaldo, H Peter Soyer
Publikováno v:
F1000Research, Vol 2 (2013)
We describe the development of a sub-millimetre skin punch biopsy device for minimally invasive and suture-free skin sampling for molecular diagnosis and research. Conventional skin punch biopsies range from 2-4 mm in diameter. Local anaesthesia is r
Externí odkaz:
https://doaj.org/article/14a56d6956a14ea19fae207c45996683
Autor:
Xianfeng Chen, Mark A. F. Kendall, Germain J. P. Fernando, Michael L. Crichton, Tarl W. Prow, Alexander B. Ansaldo
Publikováno v:
Biomaterials. 31:4562-4572
If skin's non-linear viscoelastic properties are mechanically exploited for precise antigen placement, there is tremendous promise for improved vaccines. To achieve this, we designed a Nanopatch (TM) densely packed micro-nanoprojections (>20,000/cm(2
Publikováno v:
Advances in Dermatological Sciences ISBN: 9781849733984
Proteins and peptides are coming of age as targeted biological therapies. A broad range of peptides have now been approved by the FDA and other regulatory agencies for use as therapeutics. Likewise, large proteins such as infliximab and botox are com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965183cd492c133883423de84d9b462e
https://hdl.handle.net/11541.2/126620
https://hdl.handle.net/11541.2/126620
Autor:
H. Peter Soyer, Alexander B. Ansaldo, H. Keates, Clare A. Primiero, Anthony P. Raphael, Tarl W. Prow
The delivery of therapeutics and cosmaceuticals into and/or through the skin is hindered by epidermal barriers. To overcome the skin's barriers we have developed a novel cutaneous delivery method using high aspect ratio elongate microparticles (EMPs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4366d002c04945f0e4212a11632ed86a
https://hdl.handle.net/11541.2/126440
https://hdl.handle.net/11541.2/126440
Autor:
H. Peter Soyer, Tarl W. Prow, Alexander B. Ansaldo, Lynlee L. Lin, Anthony P. Raphael, Robert L Harrold, Clare A. Primiero
Publikováno v:
F1000Research
We describe the development of a sub-millimetre skin punch biopsy device for minimally invasive and suture-free skin sampling for molecular diagnosis and research. Conventional skin punch biopsies range from 2-4 mm in diameter. Local anaesthesia is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b341b2adc0f47e2a9da227f14e4cfe02
https://hdl.handle.net/11541.2/126372
https://hdl.handle.net/11541.2/126372
Autor:
Holly J. Corbett, Alexander B. Ansaldo, Emily J. Fairmaid, Sally R. Yukiko, Lorena E. Brown, Mark A. F. Kendall, Ian H. Frazer, Christopher Flaim, Clare A. Primiero, Germain J. P. Fernando, Michael L. Crichton, Xianfeng Chen
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 152(3)
Dry-coated microprojections can deliver vaccine to abundant antigen-presenting cells in the skin and induce efficient immune responses and the dry-coated vaccines are expected to be thermostable at elevated temperatures. In this paper, we show that w