Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Alexander B Pine"'
Autor:
Stephen Y Wang, Takehiro Takahashi, Alexander B Pine, William E Damsky, Michael Simonov, Yanhua Zhang, Elizabeth Kieras, Christina C Price, Brett A King, Mark D Siegel, Gary V Desir, Alfred I Lee, Akiko Iwasaki, Hyung J Chun
Publikováno v:
PLoS Biology, Vol 19, Iss 8, p e3001373 (2021)
Challenges in using cytokine data are limiting Coronavirus Disease 2019 (COVID-19) patient management and comparison among different disease contexts. We suggest mitigation strategies to improve the accuracy of cytokine data, as we learn from experie
Externí odkaz:
https://doaj.org/article/47065a92e2014c37b9affe9000d8b92f
Autor:
Hyung J. Chun, Elias Coutavas, Alexander B. Pine, Alfred I. Lee, Vanessa L. Yu, Marcus K. Shallow, Coral X. Giovacchini, Anne M. Mathews, Brian Stephenson, Loretta G. Que, Patty J. Lee, Bryan D. Kraft
Publikováno v:
JCI Insight, Vol 6, Iss 14 (2021)
BACKGROUND Individuals recovering from COVID-19 frequently experience persistent respiratory ailments, which are key elements of postacute sequelae of SARS-CoV-2 infection (PASC); however, little is known about the underlying biological factors that
Externí odkaz:
https://doaj.org/article/2704db702156447392f5e304bc72d60a
Autor:
Cecily Allen, Samir Gautam, Wei Cheng, Alexander B. Pine, Nikolai A. Podoltsev, Amer M Zeidan, Alfred I Lee, Rory M. Shallis
Publikováno v:
Acta Haematologica. :1-6
Patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) often receive antibacterial prophylaxis. Antibacterial agents can cause elevations in the prothrombin time and international normalized ratio (INR). The impact of prophylac
Autor:
Alexander B. Pine, Matthew L. Meizlish, George Goshua, C-Hong Chang, Hanming Zhang, Jason Bishai, Parveen Bahel, Amisha Patel, Rana Gbyli, Jennifer M. Kwan, Christine H. Won, Christina Price, Charles S. Dela Cruz, Stephanie Halene, David van Dijk, John Hwa, Alfred I. Lee, Hyung J. Chun
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Increase in thrombotic and microvascular complications is emerging to be a key feature of patients with critical illness associated with COVID-19 infection. While endotheliopathy is thought to be a key factor of COVID-19-associated coagulopathy, mark
Externí odkaz:
https://doaj.org/article/b63ebb34edc7417bac3ae646450b6612
Autor:
Ayesha Butt, Tinatin Muradashvili, Sara Soliman, Fangyong Li, Adrienne J. Burns, Andrea Brooks, Sabrina Browning, Noffar Bar, Gena Borgman, George Goshua, John Hwa, Kelsey Martin, Henry Rinder, Christopher Tormey, Alexander B. Pine, Robert D. Bona, Alfred I. Lee, Natalia Neparidze
Publikováno v:
European Journal of Haematology. 109:519-525
We sought to determine risk factors for iv iron infusion-related reactions (IRR), and identify strategies for iron repletion after IRR.We conducted a retrospective chart review of patients treated in the classical hematology clinic at Yale Cancer Cen
Autor:
Andrew Silverman ScB, Sonia Taneja BA, MSc, Liliya Benchetrit BS, Peter Makusha BA, Robert L. McNamara MD, MHS, Alexander B. Pine MD, PhD
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports, Vol 6 (2018)
A 24-year-old man with history of unspecified arrhythmia presented with palpitations and chest pain. Initial electrocardiogram (ECG) revealed irregular tachycardia with varying QRS width: 150 to 200 beats per minute for narrow complexes and 300 beats
Externí odkaz:
https://doaj.org/article/0516274d19ed44fbb274c9dd91851fb1
Autor:
Carlos Fernández-Hernando, Aurelio Sonzogni, Yasuko Iwakiri, Zhaoli Sun, Alfred Ian Lee, Sandro Sironi, Matthew McConnell, Alexander B Pine, Pietro Andrea Bonaffini, Hua Qing, Xuchen Zhang, Teruo Utsumi, Nao Kawaguchi, Christina Price, Maria Alessio, Lisa Licini, Giulia Previtali, John Hwa, Mario Strazzabosco, Clarissa Valle, Reiichiro Kondo, Michela Seghezzi, Andrew Wang, Xinbo Zhang, Hyung J. Chun
Publikováno v:
Journal of Hepatology
Background and Aims COVID-19 is associated with liver injury and elevated interleukin-6 (IL-6). We hypothesized that IL-6 trans-signaling in liver sinusoidal endothelial cells (LSECs) leads to endotheliopathy (a proinflammatory and procoagulant state
Autor:
Robert D Bona, Craig Keating, Alfred Ian Lee, Donna Neuberg, Nicholas DeFilippo, Jonathan M. Siner, Matthew L Meizlish, Yuxin Liu, Stephen Wang, Kent A. Owusu, Dayna McManus, Rebecca S. Fine, Michael Mankbadi, George Goshua, Cassius Iyad Ochoa Chaar, Eric Chang, Christina Price, Hyung J. Chun, Alexander B Pine, Henry M. Rinder, Yiwen Liu, Kejal Amin
Publikováno v:
American Journal of Hematology
BackgroundThrombotic complications occur at high rates in hospitalized patients with COVID-19, yet the impact of intensive antithrombotic therapy on mortality is uncertain.Research QuestionHow does in-hospital mortality compare with intermediate-vers
Autor:
Nikolai A. Podoltsev, Allen E. Bale, Lohith Gowda, Robert Kloss, Jonica Richards, Po-Han Chen, Camille Varin-Tremblay, Alexa J. Siddon, Amy Killie, Alexander B Pine, Hadrian Mendoza
Publikováno v:
Leukemia & Lymphoma. 62:1251-1254
The single-exon gene CEBPA encodes for CCAAT/enhancer binding protein-α, a transcription factor essential for granulocyte differentiation. In acute myeloid leukemia (AML), CEBPA mutations occur at ...
Autor:
William Damsky, Yanhua Zhang, Hyung J. Chun, Elizabeth Kieras, Brett A. King, Christina Price, Mark D. Siegel, Stephen Y Wang, Akiko Iwasaki, Alexander B Pine, Takehiro Takahashi, Michael Simonov, Alfred Ian Lee, Gary V. Desir
Publikováno v:
PLoS Biology
PLoS Biology, Vol 19, Iss 8, p e3001373 (2021)
PLoS Biology, Vol 19, Iss 8, p e3001373 (2021)
Challenges in using cytokine data are limiting Coronavirus Disease 2019 (COVID-19) patient management and comparison among different disease contexts. We suggest mitigation strategies to improve the accuracy of cytokine data, as we learn from experie