Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Alexander Böhme"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract In this work, we developed a reactivity-based strategy to identify functional groups of unknown analytes, which can be applied as classifier in non-target analysis with gas chromatography. The aim of this strategy is to reduce the number of
Externí odkaz:
https://doaj.org/article/4e00e29f29ff470aac40a3d7f23e1a32
Publikováno v:
Current Research in Toxicology, Vol 4, Iss , Pp 100097- (2023)
To reduce the need for animal tests, in vitro assays are often used as alternative methods. To derive toxic doses for higher tier organisms from in vitro assay results, quantitative in vitro-in vivo extrapolation (qIVIVE) based on physiological-based
Externí odkaz:
https://doaj.org/article/eb11fed079584845aa7529592609a7d5
Autor:
Nadin Ulrich, Alexander Böhme
Publikováno v:
Environmental Advances, Vol 9, Iss , Pp 100284- (2022)
Sorption to serum albumin is essential for characterizing the distribution of chemicals in organisms. It impacts the concentration of the freely dissolved chemical in vivo and in vitro, and needs to be considered when effect concentrations at the tar
Externí odkaz:
https://doaj.org/article/adf488b4b80b4395acf132adf6ab3d47
Autor:
Beate I. Escher, Jörg Hackermüller, Tobias Polte, Stefan Scholz, Achim Aigner, Rolf Altenburger, Alexander Böhme, Stephanie K. Bopp, Werner Brack, Wibke Busch, Marc Chadeau-Hyam, Adrian Covaci, Adolf Eisenträger, James J. Galligan, Natalia Garcia-Reyero, Thomas Hartung, Michaela Hein, Gunda Herberth, Annika Jahnke, Jos Kleinjans, Nils Klüver, Martin Krauss, Marja Lamoree, Irina Lehmann, Till Luckenbach, Gary W. Miller, Andrea Müller, David H. Phillips, Thorsten Reemtsma, Ulrike Rolle-Kampczyk, Gerrit Schüürmann, Benno Schwikowski, Yu-Mei Tan, Saskia Trump, Susanne Walter-Rohde, John F. Wambaugh
Publikováno v:
Environment International, Vol 99, Iss , Pp 97-106 (2017)
The exposome encompasses an individual's exposure to exogenous chemicals, as well as endogenous chemicals that are produced or altered in response to external stressors. While the exposome concept has been established for human health, its principles
Externí odkaz:
https://doaj.org/article/1e10d437cf274ea0a58837bf35c10e71
Autor:
Ulrike Bönisch, Alexander Böhme, Tibor Kohajda, Iljana Mögel, Nicole Schütze, Martin von Bergen, Jan C Simon, Irina Lehmann, Tobias Polte
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e39817 (2012)
Epidemiological studies suggest an association between exposure to volatile organic compounds (VOCs) and adverse allergic and respiratory symptoms. However, whether VOCs exhibit a causal role as adjuvants in asthma development remains unclear.To inve
Externí odkaz:
https://doaj.org/article/94dfbbc8ecbb4033b304fac686894003
Publikováno v:
Environmental Science & Technology. 57:1692-1700
Publikováno v:
Current research in toxicology. 4
To reduce the need for animal tests
Publikováno v:
Journal of Chemical & Engineering Data. 64:5765-5774
Air–water partitioning of all nine C5 and C6 isomeric alkanones (namely, pentan-2-one, pentan-3-one, 3-methylbutan-2-one, hexan-2-one, hexan-3-one, 3-methylpentan-2-one, 4-methylpentan-2-one, 2-methylpentan-3-one, and 3,3-dimethylbutan-2-one) in wa
Autor:
Martin Krauss, Irina Lehmann, Benno Schwikowski, Alexander Böhme, David H. Phillips, Tobias Polte, Yu Mei Tan, Michaela Hein, Stefan Scholz, Annika Jahnke, John F. Wambaugh, Werner Brack, Wibke Busch, Till Luckenbach, Thomas Hartung, James J. Galligan, Natàlia Garcia-Reyero, Andrea Müller, Marc Chadeau-Hyam, Rolf Altenburger, Gary W. Miller, Adolf Eisenträger, Achim Aigner, Beate I. Escher, Adrian Covaci, Saskia Trump, Susanne Walter-Rohde, Thorsten Reemtsma, Jörg Hackermüller, Stephanie K. Bopp, Ulrike Rolle-Kampczyk, Gerrit Schüürmann, Gunda Herberth, Marja H. Lamoree, Nils Klüver, Jos C. S. Kleinjans
Publikováno v:
Escher, B I, Hackermüller, J, Polte, T, Scholz, S, Aigner, A, Altenburger, R, Böhme, A, Bopp, S K, Brack, W, Busch, W, Chadeau-Hyam, M, Covaci, A, Eisenträger, A, Galligan, J J, Garcia-Reyero, N, Hartung, T, Hein, M, Herberth, G, Jahnke, A, Kleinjans, J, Klüver, N, Krauss, M, Lamoree, M, Lehmann, I, Luckenbach, T, Miller, G W, Müller, A, Phillips, D H, Reemtsma, T, Rolle-Kampczyk, U, Schüürmann, G, Schwikowski, B, Tan, Y M, Trump, S, Walter-Rohde, S & Wambaugh, J F 2017, ' From the exposome to mechanistic understanding of chemical-induced adverse effects ', Environment International, vol. 99, pp. 97-106 . https://doi.org/10.1016/j.envint.2016.11.029
Escher, B I, Hackermüller, J, Polte, T, Scholz, S, Aigner, A, Altenburger, R, Böhme, A, Bopp, S K, Brack, W, Busch, W, Chadeau-Hyam, M, Covaci, A, Eisenträger, A, Galligan, J J, Garcia-Reyero, N, Hartung, T, Hein, M, Herberth, G, Jahnke, A, Kleinjans, J, Klüver, N, Krauss, M, Lamoree, M, Lehmann, I, Luckenbach, T, Miller, G W, Müller, A, Phillips, D H, Reemtsma, T, Rolle-Kampczyk, U, Schüürmann, G, Schwikowski, B, Tan, Y-M, Trump, S, Walter-Rohde, S & Wambaugh, J F 2016, ' From the exposome to mechanistic understanding of chemical-induced adverse effects ', Environment International . https://doi.org/10.1016/j.envint.2016.11.029
Environment International, Vol 99, Iss, Pp 97-106 (2017)
Environment international
Escher, B I, Hackermüller, J, Polte, T, Scholz, S, Aigner, A, Altenburger, R, Böhme, A, Bopp, S K, Brack, W, Busch, W, Chadeau-Hyam, M, Covaci, A, Eisenträger, A, Galligan, J J, Garcia-Reyero, N, Hartung, T, Hein, M, Herberth, G, Jahnke, A, Kleinjans, J, Klüver, N, Krauss, M, Lamoree, M, Lehmann, I, Luckenbach, T, Miller, G W, Müller, A, Phillips, D H, Reemtsma, T, Rolle-Kampczyk, U, Schüürmann, G, Schwikowski, B, Tan, Y-M, Trump, S, Walter-Rohde, S & Wambaugh, J F 2016, ' From the exposome to mechanistic understanding of chemical-induced adverse effects ', Environment International . https://doi.org/10.1016/j.envint.2016.11.029
Environment International, Vol 99, Iss, Pp 97-106 (2017)
Environment international
The exposome encompasses an individual's exposure to exogenous chemicals, as well as endogenous chemicals that are produced or altered in response to external stressors. While the exposome concept has been established for human health, its principles