Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alexander Aliev"'
Autor:
Joakim Nyberg, Caroline Bazzoli, Kay Ogungbenro, Alexander Aliev, Sergei Leonov, Stephen Duffull, Andrew C. Hooker, France Mentré
Publikováno v:
British Journal of Clinical Pharmacology. 79:6-17
Population Pharmacokinetic (PK)-Pharmacodynamic (PD) (PKPD) models are increasingly used in drug development and in academic research. Hence designing efficient studies is an important task. Follow ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df2ef0e099a70903b3ff9a5ae5d33de4
https://doi.org/10.1111/bcp.12352
https://doi.org/10.1111/bcp.12352
Publikováno v:
Communications in Statistics - Simulation and Computation. 41:717-729
We discuss a Matlab-based library for constructing optimal sampling schemes for pharmacokinetic (PK) and pharmacodynamic (PD) studies. The software relies on optimal design theory for nonlinear mixed effects models and, in particular, on the first-or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c28982f32d3afe77b95307b5b04ce97
https://doi.org/10.1080/03610918.2012.625273
https://doi.org/10.1080/03610918.2012.625273
Autor:
Joakim, Nyberg, Caroline, Bazzoli, Kay, Ogungbenro, Alexander, Aliev, Sergei, Leonov, Stephen, Duffull, Andrew C, Hooker, France, Mentré
Publikováno v:
British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, Wiley, 2015, 79 (1), pp.6-17. ⟨10.1111/bcp.12352⟩
British Journal of Clinical Pharmacology, Wiley, 2015, 79 (1), pp.6-17. ⟨10.1111/bcp.12352⟩
International audience; : Population Pharmacokinetic (PK)-Pharmacodynamic (PD) (PKPD) models are increasingly used in drug development and in academic research. Hence designing efficient studies is an important task. Following the first theoretical w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8fda94856acc654a98fec063b83cd005
https://www.hal.inserm.fr/inserm-00978789/file/BJCP_final_HAL.pdf
https://www.hal.inserm.fr/inserm-00978789/file/BJCP_final_HAL.pdf
Autor:
Alexander Aliev, Sergei L. Leonov
Publikováno v:
Contributions to Statistics ISBN: 9783319002170
We discuss different types of approximations of the individual Fisher information matrix used in population optimal design software tools and describe a Monte-Carlo option in the PkStaMp library which constructs optimal sampling schemes for populatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc7604b9946ee07cf7b033f17abdda0a
https://doi.org/10.1007/978-3-319-00218-7_17
https://doi.org/10.1007/978-3-319-00218-7_17