Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alexander A. Voorhies"'
Autor:
Sharon L. Grim, Alexander A. Voorhies, Bopaiah A. Biddanda, Sunit Jain, Stephen C. Nold, Russ Green, Gregory J. Dick
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
ABSTRACT Cyanobacterial mats profoundly influenced Earth’s biological and geochemical evolution and still play important ecological roles in the modern world. However, the biogeochemical functioning of cyanobacterial mats under persistent low-O2 co
Externí odkaz:
https://doaj.org/article/dbf9e034b41d46b6ae6fd321bb1d8e05
Autor:
Alexander A. Voorhies, C. Mark Ott, Satish Mehta, Duane L. Pierson, Brian E. Crucian, Alan Feiveson, Cherie M. Oubre, Manolito Torralba, Kelvin Moncera, Yun Zhang, Eduardo Zurek, Hernan A. Lorenzi
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Abstract Over the course of a mission to the International Space Station (ISS) crew members are exposed to a number of stressors that can potentially alter the composition of their microbiomes and may have a negative impact on astronauts’ health. H
Externí odkaz:
https://doaj.org/article/a5cf7868343a469e881872fed67500f3
Autor:
Sanjay Vashee, Timothy B. Stockwell, Nina Alperovich, Evgeniya A. Denisova, Daniel G. Gibson, Kyle C. Cady, Kristofer Miller, Krishna Kannan, Daniel Malouli, Lindsey B. Crawford, Alexander A. Voorhies, Eric Bruening, Patrizia Caposio, Klaus Früh
Publikováno v:
mSphere, Vol 2, Iss 5 (2017)
ABSTRACT Genetic engineering of cytomegalovirus (CMV) currently relies on generating a bacterial artificial chromosome (BAC) by introducing a bacterial origin of replication into the viral genome using in vivo recombination in virally infected tissue
Externí odkaz:
https://doaj.org/article/a21d363ce75f422ea5457758aa820bd9
Publikováno v:
Frontiers in Astronomy and Space Sciences, Vol 3 (2016)
Astronauts will face a host of challenges on long-duration space missions like a human expedition to Mars, including the difficulty of maintaining a balanced and healthy microbiome. The human microbiome is the collection of all microorganisms residin
Externí odkaz:
https://doaj.org/article/0870ab0294ec407fb03d413f1977d336
Autor:
Sharon L. Grim, Alexander A. Voorhies, Bopaiah A. Biddanda, Sunit Jain, Stephen C. Nold, Russ Green, Gregory J. Dick
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
Cyanobacterial mats profoundly influenced Earth’s biological and geochemical evolution and still play important ecological roles in the modern world. However, the biogeochemical functioning of cyanobacterial mats under persistent low-O2 conditions,
Autor:
Duane L. Pierson, Kelvin J. Moncera, Manolito Torralba, Yun Zhang, Cherie Oubre, Hernan Lorenzi, C. Mark Ott, Brian Crucian, Alexander A. Voorhies, Satish K. Mehta, Alan H. Feiveson, Eduardo E. Zurek
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
Over the course of a mission to the International Space Station (ISS) crew members are exposed to a number of stressors that can potentially alter the composition of their microbiomes and may have a negative impact on astronauts’ health. Here we in
Autor:
Sarah E. Stahl, Hernan Lorenzi, Alexander A. Voorhies, Sarah L. Castro-Wallace, Grace L. Douglas
Publikováno v:
Acta Astronautica. 139:463-468
The introduction of probiotic microbes into the spaceflight food system has the potential for use as a safe, non-invasive, daily countermeasure to crew microbiome and immune dysregulation. However, the microgravity effects on the stress tolerances an
Publikováno v:
Microbial Ecology. 74:1001-1008
Ubiquitous in nature, antimicrobial resistance (AMR) has existed long before the golden age of antimicrobials. While antimicrobial agents are beneficial to combat infection, their widespread use contributes to the increase in and emergence of novel r
Autor:
Daniel N. Marcus, Bopaiah A. Biddanda, Sarah D. Eisenlord, Alexander A. Voorhies, James D. Cavalcoli, Gregory J. Dick, Melissa B. Duhaime
Publikováno v:
Environmental Microbiology. 18:358-371
Summary Metagenomic and metatranscriptomic sequencing was conducted on cyanobacterial mats of the Middle Island Sinkhole (MIS), Lake Huron. Metagenomic data from 14 samples collected over 5 years were used to reconstruct genomes of two genotypes of a
Autor:
Michael G. Montague, Peter Grzesik, Sanjana Prasad, Lauren M. Oldfield, Sanjay Vashee, Robert Friedman, Claudia D. Najera, Nina Alperovich, Diya Sabrina Chandra, Vladimir N. Noskov, Derek MacMath, Alexander A. Voorhies, Prashant Desai
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Here, we present a transformational approach to genome engineering of herpes simplex virus type 1 (HSV-1), which has a large DNA genome, using synthetic genomics tools. We believe this method will enable more rapid and complex modifications of HSV-1