Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Alexander A. Lomzov"'
Publikováno v:
Molecules, Vol 29, Iss 17, p 4121 (2024)
This review article is focused on the progress made in the synthesis of 5′-α-P-modified nucleoside triphosphates (α-phosphate mimetics). A variety of α-P-modified nucleoside triphosphates (NTPαXYs, Y = O, S; X = S, Se, BH3, alkyl, amine, N-alky
Externí odkaz:
https://doaj.org/article/c357432645304560ac6f4a38bf88e4fd
Autor:
Alexey S. Chubarov, Burkhard Endeward, Maria A. Kanarskaya, Yuliya F. Polienko, Thomas F. Prisner, Alexander A. Lomzov
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 887 (2024)
Pulsed electron–electron double resonance (PELDOR) spectroscopy is a powerful method for determining nucleic acid (NA) structure and conformational dynamics. PELDOR with molecular dynamics (MD) simulations opens up unique possibilities for defining
Externí odkaz:
https://doaj.org/article/8ece1224ca4c43fa8d3df523a3842840
Publikováno v:
Molecules, Vol 29, Iss 1, p 10 (2023)
New tool development for various nucleic acid applications is an essential task in RNA nanotechnology. Here, we determined the ability of self-limited complex formation by a pair of oligoribonucleotides carrying two pairwise complementary blocks conn
Externí odkaz:
https://doaj.org/article/51ec5e1eeeb44993b2e57c2f6559aafc
Autor:
Alexey S. Chubarov, Igor P. Oscorbin, Lidiya M. Novikova, Maxim L. Filipenko, Alexander A. Lomzov, Dmitrii V. Pyshnyi
Publikováno v:
Diagnostics, Vol 13, Iss 2, p 250 (2023)
Phosphoryl guanidine (PG) is the novel uncharged modification of internucleotide phosphates of oligonucleotides. Incorporating PG modification into PCR primers leads to increased discrimination between wild-type and mutated DNA, providing extraordina
Externí odkaz:
https://doaj.org/article/c87d85b2d7ae4524acee7713157058cf
Autor:
Elena S. Dyakonova, Vladimir V. Koval, Alexander A. Lomzov, Alexander A. Ishchenko, Olga S. Fedorova
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 1515-1524 (2018)
This article presents new data on nucleotide incision repair (NIR) activity of apurinic/apyrimidinic endonuclease Apn1 of Saccharomyces cerevisiae, which is known as a key player of the base excision DNA repair (BER) pathway, see “Yeast structural
Externí odkaz:
https://doaj.org/article/37ad3400750045a88c50a76e3a257f70
Autor:
Alexander A. Lomzov, Maxim S. Kupryushkin, Andrey V. Shernyukov, Mikhail D. Nekrasov, Ilya S. Dovydenko, Dmitry A. Stetsenko, Dmitrii V. Pyshnyi
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
This article presents new data on the properties of the diastereomers of a mono-substituted phosphoryl guanidine trideoxyribonucleotides d(TpCp*A) [1,2]. The data include information on isolation, identification, treatment with snake venom phosphodie
Externí odkaz:
https://doaj.org/article/b794cec6b66840a980ddd4c3b6145f8d
Autor:
Alexey S. Chubarov, Igor P. Oscorbin, Maxim L. Filipenko, Alexander A. Lomzov, Dmitrii V. Pyshnyi
Publikováno v:
Diagnostics, Vol 10, Iss 11, p 872 (2020)
Establishing the Kirsten rat sarcoma (KRAS) mutational status is essential in terms of managing patients with various types of cancer. Allele-specific real-time polymerase chain reaction (AS-PCR) is a widely used method for somatic mutations detectio
Externí odkaz:
https://doaj.org/article/bcaf1fee25eb42eba7967f838ef059d8
Autor:
Andrey P. Rudometov, Anton N. Chikaev, Nadezhda B. Rudometova, Denis V. Antonets, Alexander A. Lomzov, Olga N. Kaplina, Alexander A. Ilyichev, Larisa I. Karpenko
Publikováno v:
Vaccines, Vol 7, Iss 3, p 83 (2019)
The construction of artificial proteins using conservative B-cell and T-cell epitopes is believed to be a promising approach for a vaccine design against diverse viral infections. This article describes the development of an artificial HIV-1 immunoge
Externí odkaz:
https://doaj.org/article/612d8625367242a99159b8cac30832ea
Autor:
Anastasia A. Zamoskovtseva, Victor M. Golyshev, Valeria A. Kizilova, Georgiy Yu. Shevelev, Dmitrii V. Pyshnyi, Alexander A. Lomzov
Publikováno v:
RSC Advances. 12:6416-6431
The development of approaches to the design of two- and three-dimensional self-assembled DNA-based nanostructures with a controlled shape and size is an essential task for applied nanotechnology, therapy, biosensing, and bioimaging. We conducted a co
Autor:
Svetlana V. Baranova, Polina V. Zhdanova, Alexander A. Lomzov, Vladimir V. Koval, Alexander A. Chernonosov
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 13889
Genome-editing systems, being some of the key tools of molecular biologists, represent a reasonable hope for progress in the field of personalized medicine. A major problem with such systems is their nonideal accuracy and insufficient selectivity. Th