Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Alexander A. Korlukov"'
Autor:
Alexander M. Scherbakov, Pavel V. Dorovatovskii, Alexander А. Korlukov, Galina I. Buravchenko, Andrey E. Shchekotikhin
Publikováno v:
Current Organic Synthesis. 17:29-39
Background: Quinoxaline 1,4-dioxides have a broad range of biological activity that causes a growing interest in their derivatives for drug discovery. Recent studies demonstrated that quinoxaline 1,4- dioxides have a promising anticancer activity and
Autor:
Danila V. Sorokin, Andrey E. Shchekotikhin, Lianet Monzote Fidalgo, Alexander M. Scherbakov, Galina I. Buravchenko, Alexander A. Korlukov, Lyubov G. Dezhenkova, Svetlana E. Solovieva, Evgeny E. Bykov
Publikováno v:
Bioorganic Chemistry. 104:104324
In this article, we describe the synthesis of 3-phenylquinoxaline-2-carbonitrile 1,4-dioxides bearing cyclic diamine residues at positions 6 or 7; the synthesis is based on the nucleophilic substitution of halogens. All synthesized 6(7)-aminoquinoxal