Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Alexander A Parent"'
Autor:
Jerome C Nwachukwu, Sathish Srinivasan, Nelson E Bruno, Alexander A Parent, Travis S Hughes, Julie A Pollock, Olsi Gjyshi, Valerie Cavett, Jason Nowak, Ruben D Garcia-Ordonez, René Houtman, Patrick R Griffin, Douglas J Kojetin, John A Katzenellenbogen, Michael D Conkright, Kendall W Nettles
Publikováno v:
eLife, Vol 3 (2014)
Resveratrol has beneficial effects on aging, inflammation and metabolism, which are thought to result from activation of the lysine deacetylase, sirtuin 1 (SIRT1), the cAMP pathway, or AMP-activated protein kinase. In this study, we report that resve
Externí odkaz:
https://doaj.org/article/fb4d849c2f4b408cb4639c209bbfccd2
Publikováno v:
European Journal of Inorganic Chemistry. 26
Autor:
Sorbarikor Piawah, Brendan John Guercio, Robert S. Stern, Michael J. Peluso, Kerry L. Kilbridge, Sherri O. Stuver, Frederick D. Tsai, Brett Glotzbecker, Marissa Winkler, Marlise R. Luskin, Mounica Vallurupalli, David A. Braun, Alexander A. Parent
Publikováno v:
Journal of Cancer Education
The Accreditation Council of Graduate Medical Education mandates that all internal medicine residents gain exposure to internal medicine subspecialties including hematology and oncology. While many residents meet this criterion through inpatient onco
Autor:
Nathanael S. Gray, Martin Sattler, Priscilla L. Yang, Alexander A. Parent, Ellen Weisberg, James D. Griffin
Publikováno v:
Canadian Journal of Physiology and Pharmacology
In response to the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), researchers are expeditiously searching for antiviral treatments able to alleviate the symptoms of infection, which can be life-threatening. Here, we provide
Autor:
Jennifer Robinson Diamond, Jason Timothy Henry, Gerald Steven Falchook, Anthony J. Olszanski, Harshabad Singh, E. Jane Leonard, Richard C. Gregory, Vicky A. Appleman, John Gibbs, Carole Harbison, Cong Li, Jessica M. Sapiro, Tomoki Yoneyama, Alexander A Parent, Vincent Chung
Publikováno v:
Journal of Clinical Oncology. 40:TPS2690-TPS2690
TPS2690 Background: Tumor resistance to immune checkpoint inhibitors (CPIs), including pembrolizumab, is common. Suggested mechanisms of resistance include reduced interferon (IFN) signaling, immune escape, and immunosuppressive tumor phenotypes. Inn
Autor:
Alexander A. Parent, Jinhua Wang, Qingsong Liu, Martin Sattler, Chengcheng Meng, Priscilla L. Yang, Nathanael S. Gray, Sara J. Buhrlage, Qingwang Liu, Ellen Weisberg, James D. Griffin
Publikováno v:
Pharmaceutical Research
The outbreak of COVID-19, the pandemic disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spurred an intense search for treatments by the scientific community. In the absence of a vaccine, the goal is to target th
Autor:
Hashini N. K. Herath, Alexander Rene Parent, Hanna Fanous, Angel Ugrinov, Christian K. Nilles
Publikováno v:
Dalton Transactions. 47:9701-9708
[Ru(tpy)(pyalk)Cl]Cl (pyalk = 2-(2′-pyridyl)-2-propanol) was synthesized and characterized crystallographically and electrochemically. Upon dissolution in water and acetonitrile, [Ru(tpy)(pyalk)Cl]Cl was found to form [Ru(tpy)(pyalk)Cl]+ and [Ru(tp
This review focuses on the studies of molecular water oxidation catalysts based on ruthenium, cobalt, copper, and iron, with emphasis given to the works undertaken thus far by the authors' group in the last decade. A particular emphasis is given on o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f07d6508e6a873ba01a879ca10fd2109
https://doi.org/10.1016/bs.adioch.2019.04.001
https://doi.org/10.1016/bs.adioch.2019.04.001
Publikováno v:
ACS Symposium Series ISBN: 9780841234376
ACS Symposium Series
ACS Symposium Series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::309238b644507caea0322fca87af98be
https://doi.org/10.1021/bk-2019-1317.ch005
https://doi.org/10.1021/bk-2019-1317.ch005
Autor:
Jennifer G. Baker, David B. Stagg, Alexander A. Parent, James P. Stice, Julie A. Pollock, Donald P. McDonnell, Suzanne E. Wardell, Holly M. Alley, Christina A. Chao, John D. Norris, Sung Hoon Kim, Ivan Spasojevic, Stephanie J. Ellison, Scott A. Lawrence, John A. Katzenellenbogen
Publikováno v:
Nature chemical biology
Clinical resistance to the second-generation antiandrogen enzalutamide in castration resistant prostate cancer (CRPC), despite persistent androgen receptor (AR) activity in tumors, highlights the unmet medical need for next generation antagonists. We