Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alexander A Boulgakov"'
Autor:
Ryan L Huizar, Chanjae Lee, Alexander A Boulgakov, Amjad Horani, Fan Tu, Edward M Marcotte, Steven L Brody, John B Wallingford
Publikováno v:
eLife, Vol 7 (2018)
Motile ciliopathies are characterized by specific defects in cilia beating that result in chronic airway disease, subfertility, ectopic pregnancy, and hydrocephalus. While many patients harbor mutations in the dynein motors that drive cilia beating,
Externí odkaz:
https://doaj.org/article/22f0578f739e4b0db977d788d91a53a5
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 2, p e1004080 (2015)
The proteomes of cells, tissues, and organisms reflect active cellular processes and change continuously in response to intracellular and extracellular cues. Deep, quantitative profiling of the proteome, especially if combined with mRNA and metabolit
Externí odkaz:
https://doaj.org/article/17cfb313554d4d7e9d487f93abbcbee4
Autor:
Xiaolong Sun, Alexander A. Boulgakov, Leilani N. Smith, Pedro Metola, Edward M. Marcotte, Eric V. Anslyn
Publikováno v:
ACS Central Science, Vol 4, Iss 7, Pp 854-861 (2018)
Externí odkaz:
https://doaj.org/article/538b57462486425d905d5cd9ac6ff02a
Autor:
Raghav Shroff, Jared W. Ellefson, Siyuan S. Wang, Alexander A. Boulgakov, Randall A. Hughes, Andrew D. Ellington
Publikováno v:
ACS synthetic biology. 11(2)
DNA is increasingly being explored as an alternative medium for digital information storage, but the potential information loss from degradation and associated issues with error during reading challenge its wide-scale implementation. To address this,
Autor:
Leo A. Joyce, Sarah R. Moor, Pedro Metola, Christopher J. Welch, Hyun Hwa Jo, Edward M. Marcotte, Alexander A. Boulgakov, Eric V. Anslyn
Publikováno v:
J Org Chem
A high-throughput screening (HTS) approach for simultaneous analysis and quantification of the percent conversion of up to 48 reactions has been developed using a thin-layer chromatography (TLC) imaging method. As a test-bed reaction, we monitored 48
Autor:
Pedro Metola, Leilani Smith, Alexander A. Boulgakov, Xiaolong Sun, Eric V. Anslyn, Edward M. Marcotte
Publikováno v:
ACS Central Science, Vol 4, Iss 7, Pp 854-861 (2018)
ACS Central Science
ACS Central Science
Photography was employed for the quantitation and differentiation of G- and V-series nerve agent mimics with the use of self-propagating cascades. Fluoride anion and thiols, released from a G-nerve agent mimic (i.e., diisopropyl fluorophosphate) and
Autor:
Chanjae Lee, Ryan L. Huizar, Edward M. Marcotte, Amjad Horani, John B. Wallingford, Alexander A. Boulgakov, Steven L. Brody, Fan Tu
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Motile ciliopathies are characterized by specific defects in cilia beating that result in chronic airway disease, subfertility, ectopic pregnancy, and hydrocephalus. While many patients harbor mutations in the dynein motors that drive cilia beating,
We extend the concept of DNA proximity ligation from a single readout per oligonucleotide pair to multiple reversible, iterative ligations re-using the same oligonucleotide molecules. Using iterative proximity ligation (IPL), we can in principle capt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14527b901e5fde11eeb2819201f4a306
https://doi.org/10.1101/470211
https://doi.org/10.1101/470211
Publikováno v:
Trends Biotechnol
The spatial distribution of molecules and cells is fundamental to understanding biological systems. Traditionally, microscopies based on electromagnetic waves such as visible light have been used to localize cellular components by direct visualizatio
Autor:
Jagannath Swaminathan, James L. Bachman, Alexander A. Boulgakov, Edward M. Marcotte, Erik T. Hernandez, Joseph Marotta, Angela M. Bardo, Amber M. Johnson, Eric V. Anslyn
Publikováno v:
Nature biotechnology
Single-protein molecules are identified in parallel through fluorescence monitoring of Edman degradation. The identification and quantification of proteins lags behind DNA-sequencing methods in scale, sensitivity, and dynamic range. Here, we show tha