Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Alexander A, Maini"'
Autor:
Alexander A. Maini, Natalia Becares, Louise China, Thais H. Tittanegro, Amit Patel, Roel P.H. De Maeyer, Nekisa Zakeri, Tu Vinh Long, Lucy Ly, Derek W. Gilroy, Alastair O’Brien
Publikováno v:
JHEP Reports, Vol 3, Iss 6, Pp 100332- (2021)
Background & Aims: Infection is a major problem in advanced liver disease secondary to monocyte dysfunction. Elevated prostaglandin (PG)E2 is a mediator of monocyte dysfunction in cirrhosis; thus, we examined PGE2 signalling in outpatients with ascit
Externí odkaz:
https://doaj.org/article/d3345bc59a7b459581475c760ed2675d
Autor:
Laura J. Pallett, Leo Swadling, Mariana Diniz, Alexander A. Maini, Marius Schwabenland, Adrià Dalmau Gasull, Jessica Davies, Stephanie Kucykowicz, Jessica K. Skelton, Niclas Thomas, Nathalie M. Schmidt, Oliver E. Amin, Upkar S. Gill, Kerstin A. Stegmann, Alice R. Burton, Emily Stephenson, Gary Reynolds, Matt Whelan, Jenifer Sanchez, Roel de Maeyer, Clare Thakker, Kornelija Suveizdyte, Imran Uddin, Ana M. Ortega-Prieto, Charlotte Grant, Farid Froghi, Giuseppe Fusai, Sabela Lens, Sofia Pérez-del-Pulgar, Walid Al-Akkad, Giuseppe Mazza, Mahdad Noursadeghi, Arne Akbar, Patrick T. F. Kennedy, Brian R. Davidson, Marco Prinz, Benjamin M. Chain, Muzlifah Haniffa, Derek W. Gilroy, Marcus Dorner, Bertram Bengsch, Anna Schurich, Mala K. Maini
Publikováno v:
Nature. 614:334-342
Autor:
Devkishan Chauhan, William Harland, Alice Gargan, Heloise Jenney, Michael Fertleman, Kate Thomas, Georgina Phillips, Alexander A Maini, Saadiq M Moledina
Publikováno v:
International Journal of General Medicine. 13:1157-1165
Background/Introduction: The coronavirus disease 2019 (COVID-19) pandemic has affected all aspects of inpatient hospital medicine with patients admitted from level 1 (general medical wards) to level 3 (intensive care). Often, there are subtle physiol
Autor:
Alexander A Maini, Marc J George, Madhur P Motwani, Richard M Day, Derek W Gilroy, Alastair J O'Brien
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165502 (2016)
Defects in neutrophil function have been implicated in a wide spectrum of clinical conditions. Several models are employed to study activated human neutrophils akin to those found at a site of inflammation. These include whole blood (WB) ex vivo stim
Externí odkaz:
https://doaj.org/article/35df6ce0dc3f4d4a8217e6ec97422d68
Autor:
Parinaaz Jalali, Derek W. Gilroy, James Glanville, Julia D. Flint, John L. Wallace, Amit Patel, Alexander A. Maini, Ali A. Hosin
Publikováno v:
The FASEB Journal. 35
ATB-346 is a hydrogen sulfide-releasing non-steroidal anti-inflammatory drug (H2 S-NSAID) derived from naproxen, which in preclinical studies has been shown to have markedly reduced gastrointestinal adverse effects. However, its anti-inflammatory pro
Autor:
James R W, Glanville, Parinaaz, Jalali, Julia D, Flint, Amit A, Patel, Alexander A, Maini, John L, Wallace, Ali A, Hosin, Derek W, Gilroy
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(10)
ATB-346 is a hydrogen sulfide-releasing non-steroidal anti-inflammatory drug (H
Autor:
Louise China, Nekisa Zakeri, Tu Vinh Long, Alexander A. Maini, Amit Patel, Thais Helena Tittanegro, Alastair O'Brien, Roel P.H. De Maeyer, Natalia Becares, Derek W. Gilroy, Lucy Ly
Publikováno v:
JHEP Reports, Vol 3, Iss 6, Pp 100332-(2021)
JHEP Reports
JHEP Reports
Background & Aims Infection is a major problem in advanced liver disease secondary to monocyte dysfunction. Elevated prostaglandin (PG)E2 is a mediator of monocyte dysfunction in cirrhosis; thus, we examined PGE2 signalling in outpatients with ascite
Autor:
Sandra Hubert, Martin Guilliams, Carlos G. Briseño, Benoit Malleret, Lai Guan Ng, Baptiste Janela, Mai Chan Lau, Josephine Lum, Kenneth M. Murphy, Philippe Musette, Yannick Simoni, Leen Vanhoutte, Bernard Malissen, Laurent F. Hennequin, Christian Wohn, Wan Ting Kong, Amit Patel, Michael G. Fehlings, Michael Poidinger, Rasha Msallam, Florent Ginhoux, Ansuman T. Satpathy, Emmanuel Vial, Jinmiao Chen, Chi Ching Goh, Francesca Zolezzi, Feriel Hacini-Rachinel, Evan W. Newell, Alexander A. Maini, Simon Yona
Publikováno v:
Immunity
Immunity, Elsevier, 2019, 50 (4), pp.1069-1083. ⟨10.1016/j.immuni.2019.03.001⟩
Immunity, 2019, 50 (4), pp.1069-1083. ⟨10.1016/j.immuni.2019.03.001⟩
IMMUNITY
IMMUNITY, 2019, 50 (4), pp.1069-1083. ⟨10.1016/j.immuni.2019.03.001⟩
Immunity, Elsevier, 2019, 50 (4), pp.1069-1083. ⟨10.1016/j.immuni.2019.03.001⟩
Immunity, 2019, 50 (4), pp.1069-1083. ⟨10.1016/j.immuni.2019.03.001⟩
IMMUNITY
IMMUNITY, 2019, 50 (4), pp.1069-1083. ⟨10.1016/j.immuni.2019.03.001⟩
Skin conventional dendritic cells (cDCs) exist as two distinct subsets, cDC1s and cDC2s, which maintain the balance of immunity to pathogens and tolerance to self and microbiota. Here, we examined the roles of dermal cDC1s and cDC2s during bacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea848e9dc854a3bae780908b4528c00
https://hal.archives-ouvertes.fr/hal-02359448
https://hal.archives-ouvertes.fr/hal-02359448
Autor:
Alastair O'Brien, Natalia Becares, Kate Bennet, Simon S. Skene, Jesmond Dalli, Louise China, Romain A. Colas, Zainib Shabir, Suvi Härmälä, Alexander A. Maini
Publikováno v:
Clinical Gastroenterology and Hepatology
Background & Aims Infection is a common cause of death in patients with cirrhosis. We investigated the association between the innate immune response and death within 3 months of hospitalization. Methods Plasma samples were collected on days 1, 5, 10
Autor:
Roseanna Hamilton, Scott Bevan, Kate M. Bennett, Zainib Shabir, Simon S. Skene, Ewan H. Forrest, Louise China, Torsten Chandler, Derek W. Gilroy, Alexander A. Maini, Natalia Becares, Alastair O'Brien
Publikováno v:
BMJ Open
China, L, Skene, S, Bennett, K, Shabir, Z, Hamilton, R, Bevan, S, Chandler, T, Maini, A, Becares, N, Gilroy, D, Forrest, E & O'Brien, A 2018, ' ATTIRE: Albumin To prevenT Infection in chronic liveR failurE : Study protocol for an interventional randomised controlled trial ', BMJ Open, vol. 8, no. 10, e023754 . https://doi.org/10.1136/bmjopen-2018-023754
China, L, Skene, S, Bennett, K, Shabir, Z, Hamilton, R, Bevan, S, Chandler, T, Maini, A, Becares, N, Gilroy, D, Forrest, E & O'Brien, A 2018, ' ATTIRE: Albumin To prevenT Infection in chronic liveR failurE : Study protocol for an interventional randomised controlled trial ', BMJ Open, vol. 8, no. 10, e023754 . https://doi.org/10.1136/bmjopen-2018-023754
IntroductionCirculating prostaglandin E2levels are elevated in acutely decompensated cirrhosis and have been shown to contribute to immune suppression. Albumin binds to and inactivates this immune-suppressive lipid mediator. Human albumin solution (H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64786370e816f1232831bb37cd015a90
https://surrey.eprints-hosting.org/852816/
https://surrey.eprints-hosting.org/852816/