Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Alexander Sommer"'
Autor:
Carola Elisa Heesemann Rosenkilde, Ditte Olsen Lützhøft, Ruben Vazquez-Uribe, Morten Otto Alexander Sommer
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Gut bacteria are known to produce bacteriocins to inhibit the growth of other bacteria. Consequently, bacteriocins have attracted increased attention as potential microbiome-editing tools. In this study we examine the inhibitory spectrum of 75 class
Externí odkaz:
https://doaj.org/article/809e82b4d03144eb8780c0503cc9688d
Autor:
Felipe Senne de Oliveira Lino, Shilpa Garg, Simone S. Li, Maria-Anna Misiakou, Kang Kang, Bruno Labate Vale da Costa, Tobias Svend-Aage Beyer-Pedersen, Thamiris Guerra Giacon, Thiago Olitta Basso, Gianni Panagiotou, Morten Otto Alexander Sommer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Bioethanol is a sustainable energy alternative and can contribute to global greenhouse-gas emission reductions by over 60%. Its industrial production faces various bottlenecks, including sub-optimal efficiency resulting from bacteria. Broad-
Externí odkaz:
https://doaj.org/article/9396922623f74000be625e3dab06bb83
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Interest in the use of engineered microbes to deliver therapeutic activities has increased in recent years. The probiotic yeast Saccharomyces boulardii has been investigated for production of therapeutics in the gastrointestinal t
Externí odkaz:
https://doaj.org/article/0cf96817042447be8c1590fca0d75c92
Autor:
Kevy Pontes Eliodório, Gabriel Caetano de Gois e Cunha, Felipe Senne de Oliveira Lino, Morten Otto Alexander Sommer, Andreas Karoly Gombert, Reinaldo Giudici, Thiago Olitta Basso
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Fully defined laboratory media have the advantage of allowing for reproducibility and comparability of results among different laboratories, as well as being suitable for the investigation of how different individual components affect microb
Externí odkaz:
https://doaj.org/article/562648f714f241b0881e6d57f149a230
Autor:
Loes van Dam, Pablo Cruz-Morales, Nabila Rodriguez Valerón, Ana Calheiros de Carvalho, Diego Prado Vásquez, Moritz Lübke, Line Kloster Pedersen, Rasmus Munk, Morten Otto Alexander Sommer, Leonie Johanna Jahn
Publikováno v:
Current Research in Food Science, Vol 9, Iss , Pp 100866- (2024)
Food production is one of the most environmentally damaging human activities. In the face of climate change, it is essential to rethink our dietary habits and explore potential alternative foods catering both towards human and planetary needs. Fungal
Externí odkaz:
https://doaj.org/article/357ec89bd9d54cafb9022ed4a9785464
Autor:
Valeria Iannone, Ambrin Farizah Babu, Johnson Lok, Carlos Gómez-Gallego, Giuseppe D'Auria, Ruben Vazquez-Uribe, Troels Holger Vaaben, Mareike Bongers, Santtu Mikkonen, Maija Vaittinen, Ida Tikkanen, Mikko Kettunen, Anton Klåvus, Ratika Sehgal, Dorota Kaminska, Jussi Pihlajamaki, Kati Hanhineva, Hani El-Nezami, Morten Otto Alexander Sommer, Marjukka Kolehmainen
Publikováno v:
Molecular Metabolism, Vol 78, Iss , Pp 101823- (2023)
Objective: Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is the most prevalent liver disease globally, yet no therapies are approved. The effects of Escherichia coli Nis
Externí odkaz:
https://doaj.org/article/e3dd49cbb92443919ba14a867061e16d
Autor:
Karl Alex Hedin, Vanessa Emily Rees, Hongbin Zhang, Vibeke Kruse, Ruben Vazquez-Uribe, Morten Otto Alexander Sommer
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Mouse models are commonly used to study the colonisation profiles of microorganisms introduced to the gastrointestinal tract. Three commonly used mouse models include conventional, germ-free, and antibiotic-treated mice. However, colonisatio
Externí odkaz:
https://doaj.org/article/be46e261a407491b896af1ba7bfb6baf
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
The human gastrointestinal tract is a complex and dynamic environment, playing a crucial role in human health. Microorganisms engineered to express a therapeutic activity have emerged as a novel modality to manage numerous diseases. Such advanced mic
Externí odkaz:
https://doaj.org/article/d631c645ec964b668279c2563b7808a5
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
One of the biggest challenges for oral drug absorption is the epithelial barrier of the gastrointestinal tract. The use of cell-penetrating peptides (CPPs) to modulate the epithelial barrier function is known to be an effective strategy to improve dr
Externí odkaz:
https://doaj.org/article/823cbc55caf14812a7722dde708d38c6
Autor:
Ruben V. Uribe, Christin Rathmer, Leonie Johanna Jahn, Mostafa Mostafa Hashim Ellabaan, Simone S. Li, Morten Otto Alexander Sommer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract In the age of antibiotic resistance and precise microbiome engineering, CRISPR-Cas antimicrobials promise to have a substantial impact on the way we treat diseases in the future. However, the efficacy of these antimicrobials and their mechan
Externí odkaz:
https://doaj.org/article/abe1e98c25074767ad4e8e079518f630