Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alexander Iphöfer"'
Autor:
Mikael Altun, Thomas S Walter, Holger B Kramer, Patrick Herr, Alexander Iphöfer, Johan Boström, Yael David, Alia Komsany, Nicola Ternette, Ami Navon, David I Stuart, Jingshan Ren, Benedikt M Kessler
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0115344 (2015)
Ovarian tumor domain containing proteases cleave ubiquitin (Ub) and ubiquitin-like polypeptides from proteins. Here we report the crystal structure of human otubain 2 (OTUB2) in complex with a ubiquitin-based covalent inhibitor, Ub-Br2. The ubiquitin
Externí odkaz:
https://doaj.org/article/df235d64d4d94ee6b0d0d35d67ff82c0
Autor:
David M Maahs, Justyna Siwy, Angel Argilés, Marie Cerna, Christian Delles, Anna F Dominiczak, Nathalie Gayrard, Alexander Iphöfer, Lothar Jänsch, George Jerums, Karel Medek, Harald Mischak, Gerjan J Navis, Johannes M Roob, Kasper Rossing, Peter Rossing, Ivan Rychlík, Eric Schiffer, Roland E Schmieder, Thomas C Wascher, Brigitte M Winklhofer-Roob, Lukas U Zimmerli, Petra Zürbig, Janet K Snell-Bergeon
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
The pathogenesis of diabetes mellitus (DM) is variable, comprising different inflammatory and immune responses. Proteome analysis holds the promise of delivering insight into the pathophysiological changes associated with diabetes. Recently, we ident
Externí odkaz:
https://doaj.org/article/8ae37ae79cf8494a88e94645e45d94ce
Autor:
Nicola Ternette, Jingshan Ren, Ami Navon, Alia Komsany, Alexander Iphöfer, Yael David, Patrick Herr, Mikael Altun, Thomas S. Walter, Benedikt M. Kessler, Johan Boström, David I. Stuart, Holger B. Kramer
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0115344 (2015)
PLoS ONE
PLoS ONE
Ovarian tumor domain containing proteases cleave ubiquitin (Ub) and ubiquitin-like polypeptides from proteins. Here we report the crystal structure of human otubain 2 (OTUB2) in complex with a ubiquitin-based covalent inhibitor, Ub-Br2. The ubiquitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a009121e95b2b5a39ea40afa6cda32
https://doi.org/10.1371/journal.pone.0115344
https://doi.org/10.1371/journal.pone.0115344
Autor:
Benedikt M. Kessler, Ronald Frank, Raimo Franke, Tatjana Arnold, Antje Ritter, Anne Kummer, Manfred Nimtz, Alexander Iphöfer, Lothar Jänsch, Joop van den Heuvel
Publikováno v:
ChemBioChem. 13:1416-1420
Autor:
Katalin Di Gleria, Edda Fiebiger, Alexander Iphöfer, Mariola J. Edelmann, Mikael Altun, Benedikt M. Kessler, Holger B. Kramer, Masato Akutsu, Sirano Dhe-Paganon
Publikováno v:
Biochemical Journal. 418:379-390
OTUB (otubain) 1 is a human deubiquitinating enzyme that is implicated in mediating lymphocyte antigen responsiveness, but whose molecular function is generally not well defined. A structural analysis of OTUB1 shows differences in accessibility to th
Autor:
Karel Medek, Ivan Rychlik, George Jerums, Justyna Siwy, Kasper Rossing, Harald Mischak, Christian Delles, Àngel Argilés, Petra Zürbig, Lukas U. Zimmerli, Lothar Jänsch, Janet K. Snell-Bergeon, Anna F. Dominiczak, Marie Cerna, Roland E. Schmieder, David M. Maahs, Johannes M. Roob, Nathalie Gayrard, Alexander Iphöfer, Gerjan Navis, Brigitte M. Winklhofer-Roob, Peter Rossing, Eric Schiffer, Thomas C. Wascher
Publikováno v:
PLoS ONE
PLoS ONE; Vol 5
PLoS ONE, 5(9):13051. PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 5, Iss 9 (2010)
PLoS ONE; Vol 5
PLoS ONE, 5(9):13051. PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 5, Iss 9 (2010)
Background: The pathogenesis of diabetes mellitus (DM) is variable, comprising different inflammatory and immune responses. Proteome analysis holds the promise of delivering insight into the pathophysiological changes associated with diabetes. Recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8f414580ab409861b432f72c2e5953
https://hdl.handle.net/10033/129760
https://hdl.handle.net/10033/129760
Autor:
Eric Schiffer, Alexander Iphöfer, Yung C. Chen, Constantin von zur Mühlen, Karlheinz Peter, Andreas Zirlik, Christoph Bode, Nay M. Htun, Lothar Jänsch, Petra Zürbig, Irene Neudorfer, Christine Sackmann, Harald Mischak
Publikováno v:
Scopus-Elsevier
Molecular & Cellular Proteomics; Vol 11
Molecular & Cellular Proteomics
Molecular & Cellular Proteomics; Vol 11
Molecular & Cellular Proteomics
Noninvasive diagnosis of atherosclerosis via single biomarkers has been attempted but remains elusive. However, a previous polymarker or pattern approach of urine polypeptides in humans reflected coronary artery disease with high accuracy. The aim of
Autor:
Mariola J. Edelmann, Alexander Iphöfer, Masato Akutsu, Mikael Altun, Katalin di gleria, Holger B. Kramer, Edda Fiebiger, Sirano Dhe-paganon, Benedikt M. Kessler
Publikováno v:
Biochemical Journal; Mar2009, Vol. 418 Issue 2, p379-390, 12p
Autor:
Walter Kolch, David Bouyssié, Lothar Jänsch, Andreas Pich, Harald Mischak, Jan Novak, Antonia Vlahou, Manousos Makridakis, Li-Shun Wang, Martin Norling, Petra Zürbig, Gry H. Dihazi, Michalis Aivaliotis, Visith Thongboonkerd, Julia Franke, Erik Bongcam-Rudloff, Alexander Iphöfer, Jochen Metzger, Joost P. Schanstra, Chrystelle Lacroix, Bernard Monsarrat, Andrew R. Pitt, Jérôme Garin, Anne Gonzalez de Peredo, Justyna Siwy, Hitoshi Suzuki, Michal Mrug, Christophe Masselon, Hassan Dihazi, Magali Court, Jerome Zoidakis
Publikováno v:
Scopus-Elsevier
PROTEOMICS-Clinical Applications
PROTEOMICS-Clinical Applications, Wiley-VCH Verlag, 2011, 4 (4), pp.464-478. ⟨10.1002/prca.200900189⟩
PROTEOMICS-CLINICAL APPLICATIONS
PROTEOMICS-CLINICAL APPLICATIONS; Vol 4
PROTEOMICS-Clinical Applications
PROTEOMICS-Clinical Applications, Wiley-VCH Verlag, 2011, 4 (4), pp.464-478. ⟨10.1002/prca.200900189⟩
PROTEOMICS-CLINICAL APPLICATIONS
PROTEOMICS-CLINICAL APPLICATIONS; Vol 4
Urine proteomics is emerging as a powerful tool for biomarker discovery. The purpose of this study is the development of a well-characterized "real life" sample that can be used as reference standard in urine clinical proteomics studies.We report on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2ee62c0b344e88722632fdd87beb10
http://www.scopus.com/inward/record.url?eid=2-s2.0-77953722868&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-77953722868&partnerID=MN8TOARS