Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alexander, von der Malsburg"'
Autor:
Leticia Prates Roma, Anna-Florentine Schiuma, Kai Schuh, Martin van der Laan, Jan Dudek, Julia Schwemmlein, Sarah Atighetchi, Michael Böhm, Edoardo Bertero, Christopher Carlein, Andreas Müller, Carolin Brune, Peter Rehling, Markus Hoth, Andrey Kazakov, Michaela Kuhn, Mathias Hohl, Christoph Maack, Ulrich Laufs, Michael Kohlhaas, Vasco Sequeira, Ilona Kutschka, Marco Abeßer, Kai Münker, Alexander Nickel, Reinhard Kappl, Karina von der Malsburg, Alexander von der Malsburg
Publikováno v:
Circulation. 144:1694-1713
Background: Barth syndrome (BTHS) is caused by mutations of the gene encoding tafazzin, which catalyzes maturation of mitochondrial cardiolipin and often manifests with systolic dysfunction during early infancy. Beyond the first months of life, BTHS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dc7d7ca51902412ab37f2eea26fcb04
https://doi.org/10.1161/circulationaha.121.053755
https://doi.org/10.1161/circulationaha.121.053755
Autor:
Tobias Bock-Bierbaum, Kathrin Funck, Florian Wollweber, Elisa Lisicki, Janina Laborenz, Jeffrey K. Noel, Manuel Hessenberger, Alexander von der Malsburg, Karina von der Malsburg, Carola Bernert, Séverine Kunz, Dietmar Riedel, Hauke Lilie, Stefan Jakobs, Martin van der Laan, Oliver Daumke
Mitochondrial cristae membranes are the oxidative phosphorylation sites in cells. Crista junctions (CJs) form the highly curved neck regions of cristae and are thought to function as selective entry gates into the cristae space. Little is known about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c03080a8f8a6e880cf1c3b229f00fa79
https://doi.org/10.1101/2022.03.30.486340
https://doi.org/10.1101/2022.03.30.486340
Autor:
Edoardo, Bertero, Alexander, Nickel, Michael, Kohlhaas, Mathias, Hohl, Vasco, Sequeira, Carolin, Brune, Julia, Schwemmlein, Marco, Abeßer, Kai, Schuh, Ilona, Kutschka, Christopher, Carlein, Kai, Münker, Sarah, Atighetchi, Andreas, Müller, Andrey, Kazakov, Reinhard, Kappl, Karina, von der Malsburg, Martin, van der Laan, Anna-Florentine, Schiuma, Michael, Böhm, Ulrich, Laufs, Markus, Hoth, Peter, Rehling, Michaela, Kuhn, Jan, Dudek, Alexander, von der Malsburg, Leticia, Prates Roma, Christoph, Maack
Publikováno v:
Circulation. 144(21)
Barth syndrome (BTHS) is caused by mutations of the gene encoding tafazzin, which catalyzes maturation of mitochondrial cardiolipin and often manifests with systolic dysfunction during early infancy. Beyond the first months of life, BTHS cardiomyopat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcf43f159d12506e4114c3628bb70e29
https://pubmed.ncbi.nlm.nih.gov/34648376
https://pubmed.ncbi.nlm.nih.gov/34648376
Autor:
Martin A. Michel, Alexander von der Malsburg, Felix Randow, Claudio Pathe, David Komander, Jessica Noad
Publikováno v:
Nature Microbiology. 2
Cell-autonomous immunity relies on the ubiquitin coat surrounding cytosol-invading bacteria functioning as an ‘eat-me’ signal for xenophagy. The origin, composition and precise mode of action of the ubiquitin coat remain incompletely understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77bc9758767a77ce15b538048f16eb87
https://doi.org/10.1038/nmicrobiol.2017.63
https://doi.org/10.1038/nmicrobiol.2017.63
Publikováno v:
Journal of Biological Chemistry. 286:37858-37865
The human MxA protein is an interferon-induced large GTPase with antiviral activity against a wide range of viruses, including influenza viruses. Recent structural data demonstrated that MxA oligomerizes into multimeric filamentous or ring-like struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b735b6338ef7c4c3db305a185d673cc8
https://doi.org/10.1074/jbc.m111.249037
https://doi.org/10.1074/jbc.m111.249037
Autor:
Gunnar F. Schröder, Alexander von der Malsburg, Alexej Dick, Oliver Daumke, Otto Haller, Katja Faelber, Song Gao, Georg Kochs
Publikováno v:
Immunity. 35:514-525
SummaryHuman myxovirus resistance protein 1 (MxA) is an interferon-induced dynamin-like GTPase that acts as a cell-autonomous host restriction factor against many viral pathogens including influenza viruses. To study the molecular principles of its a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1018cc063a9d76bbcde57c45b6e8298a
https://doi.org/10.1016/j.immuni.2011.07.012
https://doi.org/10.1016/j.immuni.2011.07.012
Autor:
Oliver Daumke, Alexander von der Malsburg, Laura Graf, Daniel Olal, Song Gao, Alexej Dick, Georg Kochs
Myxovirus resistance (Mx) GTPases are induced by interferon and inhibit multiple viruses, including influenza and human immunodeficiency viruses. They have the characteristic domain architecture of dynamin-related proteins with an N-terminal GTPase (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c70f366efeff085b86b8bd6d6c8855
https://europepmc.org/articles/PMC4432294/
https://europepmc.org/articles/PMC4432294/
Autor:
Alexander von der Malsburg, Claudio Pathe, Cara J. Ellison, Keith B. Boyle, Michal P. Wandel, Felix Randow, Emma I. Werner, John R. Rohde
Publikováno v:
Cell Host & Microbe. 22:507-518.e5
Summary Interferon exposure boosts cell-autonomous immunity for more efficient pathogen control. But how interferon-enhanced immunity protects the cytosol against bacteria and how professionally cytosol-dwelling bacteria avoid clearance are insuffici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e6966be7c60eb24b58063852b36132
https://doi.org/10.1016/j.chom.2017.09.007
https://doi.org/10.1016/j.chom.2017.09.007
Publikováno v:
Small GTPases. 1:62-64
The dynamin-like MxA GTP ase (Myxovirus resistance protein 1) mediates cellular resistance against a wide range of viruses. MxA is composed of an amino-terminal G domain, a middle domain and a carboxy-terminal GTPase effector domain. We recently dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5b1c5ddb8894e68abb2843eb9903c5
https://doi.org/10.4161/sgtp.1.1.12989
https://doi.org/10.4161/sgtp.1.1.12989
Autor:
Benjamin Schusser, Alexander von der Malsburg, Sonja Härtle, Bernd Kaspers, Antje Reuter, Peter Staeheli, Steffen Weigend, Nicola Penski
The type I interferon (IFN) system plays an important role in antiviral defense against influenza A viruses (FLUAV), which are natural chicken pathogens. Studies of mice identified the Mx1 protein as a key effector molecule of the IFN-induced antivir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353980c13c5b068e6cb6f8391c8d5189
https://europepmc.org/articles/PMC3147972/
https://europepmc.org/articles/PMC3147972/