Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Alexander, Wree"'
Autor:
Johanna Reißing, Marie Berres, Pavel Strnad, Alexander Wree, Maria Eugenia Inzaugarat, Christian Trautwein, Tony Bruns, Henning Wolfgang Zimmermann
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 4, Pp 517-538 (2024)
Background & Aims: Type 2 immune responses contribute to liver fibrosis in parasite infections, but their role in other liver diseases is less well understood. Here, we aimed at unravelling mechanisms involved in T helper 2 (Th2) T-cell polarization,
Externí odkaz:
https://doaj.org/article/3ffa487cb3d548f9bcf2f9e10327e30b
Autor:
Sven H. Loosen, Fabian Benz, Raphael Mohr, Philipp A. Reuken, Theresa H. Wirtz, Lioba Junker, Christian Jansen, Carsten Meyer, Michael Praktiknjo, Alexander Wree, Johanna Reißing, Münevver Demir, Wenyi Gu, Mihael Vucur, Robert Schierwagen, Andreas Stallmach, Anselm Kunstein, Johannes Bode, Christian Trautwein, Frank Tacke, Tom Luedde, Tony Bruns, Jonel Trebicka, Christoph Roderburg
Publikováno v:
JHEP Reports, Vol 6, Iss 5, Pp 101054- (2024)
Background & Aims: Transjugular intrahepatic portosystemic shunt (TIPS) is the most effective therapy for complications of portal hypertension. However, clinical outcomes following TIPS placement vary widely between patients and identifying ideal can
Externí odkaz:
https://doaj.org/article/1c0266d113654c7496f7e96b4601da0f
Autor:
Linde Kehmann, Marie-Luise Berres, Maria Gonzalez-Carmona, Dominik P. Modest, Raphael Mohr, Alexander Wree, Marino Venerito, Christian Strassburg, Verena Keitel, Christian Trautwein, Tom Luedde, Christoph Roderburg
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background The prognosis of patients with advanced biliary tract cancer (BTC) who have progressed on gemcitabine plus cisplatin is dismal. Trifluridine/tipiracil (FTD/TPI) and irinotecan have proven efficacy in different gastrointestinal mal
Externí odkaz:
https://doaj.org/article/adcfd14080b94e43bba7e5c89b37d3ba
Autor:
Klaus Stahl, Friederike Klein, Torsten Voigtländer, Anika Großhennig, Thorsten Book, Tobias Müller, Alexander Wree, Armin Kuellmer, Jochen Weigt, Alexander Dechene, Edris Wedi, Arne Kandulski, Christian M. Lange, Dennis Holzwart, Dorothee von Witzendorff, Kristina I. Ringe, Heiner Wedemeyer, Benjamin Heidrich, for the BISCIT Study group
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Progress of cholangitis to cholangiosepsis is a frequent observation in patients with secondary sclerosing cholangitis in critically ill patients (SSC–CIP). Adequate biliary drainage may reduce episodes of cholangiosepsis and th
Externí odkaz:
https://doaj.org/article/d7f2563894ef435fb32c8e67230d175f
Autor:
Sven H Loosen, Max Schulze‐Hagen, Mihael Vucur, Joao Gorgulho, Pia Paffenholz, Fabian Benz, Raphael Mohr, Münevver Demir, Alexander Wree, Christiane Kuhl, Christian Trautwein, Frank Tacke, Philipp Bruners, Tom Luedde, Christoph Roderburg
Publikováno v:
JGH Open, Vol 5, Iss 3, Pp 356-363 (2021)
Abstract Background and Aim Transarterial chemoembolization (TACE) represents a standard of care for patients with intermediate‐stage hepatocellular carcinoma (HCC) or liver metastases. However, identification of the ideal candidates for TACE thera
Externí odkaz:
https://doaj.org/article/bf4fa54aed5a4afc97dcb6bfd63d1339
Autor:
Christian Liedtke, Yulia A. Nevzorova, Tom Luedde, Henning Zimmermann, Daniela Kroy, Pavel Strnad, Marie-Luise Berres, Jürgen Bernhagen, Frank Tacke, Jacob Nattermann, Ulrich Spengler, Tilman Sauerbruch, Alexander Wree, Zeinab Abdullah, René H. Tolba, Jonel Trebicka, Twan Lammers, Christian Trautwein, Ralf Weiskirchen
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
The Transregional Collaborative Research Center “Organ Fibrosis: From Mechanisms of Injury to Modulation of Disease” (referred to as SFB/TRR57) was funded for 13 years (2009–2021) by the German Research Council (DFG). This consortium was hosted
Externí odkaz:
https://doaj.org/article/854f4678a7ef45078def2dc8a24e231a
Autor:
Fabian Jost‐Brinkmann, Münevver Demir, Alexander Wree, Tom Luedde, Sven H. Loosen, Tobias Müller, Frank Tacke, Christoph Roderburg, Raphael Mohr
Publikováno v:
Alimentary Pharmacology & Therapeutics. 57:1313-1325
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d99b2d482477823bc172430f1a22520
https://doi.org/10.1111/apt.17441
https://doi.org/10.1111/apt.17441
Publikováno v:
Hepatic Oncology, Vol 7, Iss 2 (2020)
For almost a decade, systemic therapy of advanced hepatocellular carcinoma (HCC) was limited to the tyrosine kinase inhibitor (TKI) sorafenib. Different agents including checkpoint inhibitors, TKIs and anti-VEGFR antibodies demonstrated efficacy in t
Externí odkaz:
https://doaj.org/article/876312c1c6284b3497279bf78232b983
Publikováno v:
Hepatic Oncology, Vol 7, Iss 1 (2020)
Hepatocellular carcinoma (HCC) is the most common primary liver cancer. Most patients present with advanced or metastatic HCC at diagnosis and face a dismal prognosis. Tyrosine kinases are the gold standard treatment for this disease but yield limite
Externí odkaz:
https://doaj.org/article/75841ad628bb4212af0ee4d5d1cfdc04
Autor:
Fabian Benz, Andreas Bogen, Michael Praktiknjo, Christian Jansen, Carsten Meyer, Alexander Wree, Muenevver Demir, Sven Loosen, Mihael Vucur, Robert Schierwagen, Frank Tacke, Jonel Trebicka, Christoph Roderburg
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231701 (2020)
Liver cirrhosis represents the common end-stage of chronic liver diseases regardless of its etiology. Patients with compensated disease are mostly asymptomatic, however, progression to a decompensated disease stage is common. The available stratifica
Externí odkaz:
https://doaj.org/article/9836b6db948a46ed9dcb15b074781d39